Tonsillitis

Pipeline Programs

Companies

Clinical Trials

Approved Products

Pipeline by Development Stage

Preclinical

Phase 1

Phase 1/2

Phase 2

Phase 2/3

Phase 3

On Market

Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule

1100%

+ 4 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Pre

P1/2

P2/3

Mkt

PfizerNEW YORK, NY

2 programs

FentanylPhase 41 trial

CelecoxibPhase 2Small Molecule1 trial

Active Trials

NCT00583453Completed18Est. May 2016

NCT00654511Completed101Est. Oct 2008

SanofiPARIS, France

2 programs

TelithromycinPHASE_35 trials

pristinamycinPHASE_31 trial

Active Trials

NCT00315042Terminated314Est. Aug 2006

NCT00315549Terminated233Est. Sep 2006

NCT00315003Terminated1,500Est. Jul 2006

+3 more trials

MedtronicNJ - Phillipsburg

1 program

PEAK PlasmaBlade TnAN/A1 trial

Active Trials

NCT01193556Terminated51Est. Apr 2012

Trial Timeline

Clinical trial activity over time

2021

2022

2023

2024

2025

2026

SanofiTelithromycin

PfizerFentanyl

SanofiTelithromycin

Sanofipristinamycin

SanofiTelithromycin

Showing 15 of 23 trials with date data

Clinical Trials (23)

Total enrollment: 11,938 patients across 23 trials

NCT00315601 SanofiTelithromycin

Intrapulmonary Pharmacokinetics of Antibiotics

Start: Jan 2006Est. completion: Nov 200635 patients

Phase 4Terminated

NCT00288223 SanofiTelithromycin

Telithromycin in Acute Exacerbation of Chronic Bronchitis

Start: Jan 2006Est. completion: Jan 200754 patients

Phase 4Terminated

NCT00245440 SanofiTelithromycin

Study to Measure the Impact of Antibiotics on Bacterial Flora in Adults With Acute Sinusitis

Start: Dec 2005Est. completion: Jul 2006192 patients

Phase 4Terminated

NCT00237445 SanofiTelithromycin

Study Comparing the Clinical Efficacy and Health Outcomes of Outpatients With Mild to Moderate Community-Acquired Pneumonia (CAP) Treated With Either Telithromycin Once Daily for 7 Days, or Azithromycin Once Daily for 5 Days

Start: Nov 2005Est. completion: Sep 2006110 patients

Phase 4Terminated

NCT00245453 SanofiTelithromycin

Outpatient Registry Trial of Respiratory Tract Infections in Adults

Start: Oct 2005Est. completion: Jul 20060

Phase 4Withdrawn

NCT00261105 SanofiTelithromycin

Telithromycin in Respiratory Tract Infections

Start: Feb 2005Est. completion: Dec 2005

Phase 4Completed

NCT00654511 PfizerFentanyl

Dexmedetomidine for Immediate Perioperative Analgesia in Pediatric Patients Undergoing Tonsillectomy

Start: Jan 2005Est. completion: Oct 2008101 patients

Phase 4Completed

NCT00174694 SanofiTelithromycin

CHOOSE : Telithromycin, Acute Bacterial Sinusitis

Start: Nov 2004298 patients

Phase 4Completed

NCT00546676 SanofiTelithromycin

Ketek in CAP / AECB in Ambulatory Adult Patients

Start: May 2004Est. completion: Dec 2004174 patients

Phase 4Completed

NCT00132938 SanofiTelithromycin

PERSPECTIVE: Telithromycin - Acute Exacerbation of Chronic Bronchitis

Start: Jan 2004Est. completion: May 20065,660 patients

Phase 4Completed

NCT00538018 SanofiTelithromycin

Telithromycin, Treating Adult Outpatients With Mild to Moderate Community-acquired Pneumonia (CAP) in High Bacterial Resistance Areas

Start: Jan 2003Est. completion: Jun 2004978 patients

Phase 4Completed

NCT00538148 SanofiTelithromycin

Telithromycin: in the Treatment of Acute Exacerbation of Chronic Bronchitis in Adult Outpatients With COPD

Start: Nov 2002Est. completion: Sep 2004668 patients

Phase 4Completed

NCT00393744 Sanofipristinamycin

Efficacy Study of Pristinamycin Versus Amoxicillin to Treat Tonsillitis Induced by Streptococcus in Children

Start: Oct 2006395 patients

Phase 3Completed

NCT00315042 SanofiTelithromycin

TELI TON - Telithromycin in Tonsillitis

Start: Mar 2006Est. completion: Aug 2006314 patients

Phase 3Terminated

NCT00315549 SanofiTelithromycin

TELI TAD - Telithromycin in Tonsillitis in Adolescents and Adults

Start: Feb 2006Est. completion: Sep 2006233 patients

Phase 3Terminated

NCT00315003 SanofiTelithromycin

TELI COM - Telithromycin in Children With Otitis Media

Start: Jan 2006Est. completion: Jul 20061,500 patients

Phase 3Terminated

NCT00174811 SanofiTelithromycin

Comparative Study to Evaluate the Efficacy and Safety of Telithromycin Given Once Daily Versus Cefuroxime Axetil Given Twice Daily in Children With Middle Ear Infections

Start: Jun 2005Est. completion: Jun 2006639 patients

Phase 3Terminated

NCT00408135 SanofiTelithromycin

Japanese Study Evaluating Safety, Efficacy and Acceptability of Telithromycin in Children With Infections

Start: Aug 2004Est. completion: May 2005111 patients

Phase 3Completed

NCT00638534 SanofiTelithromycin

Japanese Study Evaluating the Effects of Telithromycin in Children With Acute Otitis Media

Start: Feb 2004Est. completion: Oct 200456 patients

Phase 3Completed

NCT00273520 SanofiTelithromycin

TELICAST : Telithromycin in Acute Exacerbations of Asthma

Start: Jan 2003Est. completion: May 2004

Phase 3Completed

NCT00537563 SanofiTelithromycin

AMS VS MOXI Ketek vs Avelox in AMS

Start: Dec 2002Est. completion: Sep 2003351 patients

Phase 3Completed

NCT00583453 PfizerCelecoxib

Celecoxib as a Post-tonsillectomy Pain Medication

Start: Oct 2007Est. completion: May 201618 patients

Phase 2Completed

NCT01193556 MedtronicPEAK PlasmaBlade TnA

PEAK PlasmaBlade TnA Versus Traditional Electrosurgery in Subcapsular Tonsillectomy

Start: Jul 2010Est. completion: Apr 201251 patients

N/ATerminated

Phase Legend

Preclinical— Lab & animal studies

Phase 1— Safety & dosing

Phase 2— Efficacy testing

Phase 3— Large-scale trials

On Market— Approved & available

Key Insights

3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.