Tobacco Use Disorder
2
Pipeline Programs
4
Companies
4
Clinical Trials
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
0
1
Early DiscoveryClinical DevelopmentMarket
Competitive Landscape
4 companies ranked by most advanced pipeline stage
J&
Johnson & JohnsonNEW BRUNSWICK, NJ
2 programs1
1
Bupropion SRPhase 41 trial
CHERLPhase 11 trial
Active Trials
PfizerNEW YORK, NY
1 programSmoking-induced Dopamine Release: a [11C]-(+)-PHNO PET Study in HumansN/A1 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
Johnson & JohnsonBupropion SR
Johnson & JohnsonCHERL
PfizerSmoking-induced Dopamine Release: a [11C]-(+)-PHNO PET Study in Humans
Alliance PharmaceuticalsFresh lime
Clinical Trials (4)
Total enrollment: 150 patients across 4 trials
Pilot Study of Bupropion for Smoking Cessation in Postpartum Non-breastfeeding Women
Start: Mar 2005Est. completion: Mar 200640 patients
Phase 4Terminated
CHERL, Connecting Primary Care Patients With Community Resources to Facilitate Behavior Change
Start: Jan 2006Est. completion: Feb 2007
Phase 1Unknown
Smoking-induced Dopamine Release: a [11C]-(+)-PHNO PET Study in Humans
Start: Feb 2011Est. completion: Mar 201310 patients
N/ACompleted
Fresh Lime Alone for Smoking Cessation
Start: Mar 2009Est. completion: Sep 2009100 patients
N/ACompleted
Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
4 companies competing in this space