Tobacco Dependence

4
Pipeline Programs
1
Companies
24
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
0
0
1
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

1 companies ranked by most advanced pipeline stage

J&
Johnson & JohnsonNEW BRUNSWICK, NJ
8 programs
2
1
1
Nicotine GumPhase 41 trial
Nicotine SprayPhase 31 trial
Nicorette Strongmint lozenge 4 mgPhase 11 trial
NicotinePhase 11 trial
Code STDN/A1 trial
+3 more programs
Active Trials
NCT01238640Completed84Est. Nov 2008
NCT03398876Completed24Est. Apr 2018
NCT02506829Completed182Est. May 2019
+9 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Johnson & JohnsonNicotine Gum
Johnson & JohnsonNicotine
Johnson & JohnsonNicotine Spray
Johnson & JohnsonNicotine
Johnson & JohnsonNicotine
Johnson & JohnsonNicorette Strongmint lozenge 4 mg
Johnson & JohnsonNicotine
Johnson & JohnsonNicotine
Johnson & JohnsonNicotine
Johnson & JohnsonNicotine
Johnson & JohnsonNicotine
Johnson & JohnsonNicotine Medicated Gum
Johnson & JohnsonNicotine
Johnson & JohnsonNicotine
Johnson & JohnsonNicotine

Showing 15 of 24 trials with date data

Clinical Trials (24)

Total enrollment: 3,723 patients across 24 trials

Evaluation of the Safety Profile, Quit and Reduction Rate After Nicorette® Gum and Patch Treatment

Start: Feb 2009Est. completion: Nov 2009300 patients
Phase 4Completed

Combination Medications vs. Patch Alone for Medically-Ill Smokers

Start: Sep 2005Est. completion: Jan 2008127 patients
Phase 4Completed

Study to Determine the Efficacy and Safety of a Novel Nicotine Replacement Therapy

Start: Jan 2015Est. completion: Feb 20161,198 patients
Phase 3Completed

Early Effects of a New Oral Nicotine Replacement Product and NiQuitin™ Lozenge

Start: Feb 2010Est. completion: May 2010200 patients
Phase 2Completed

A Study to Assess the Nicotine Pharmacokinetics, Tolerability and Safety With a New Oral Nicotine Replacement Product in Healthy Japanese Smokers

Start: Dec 2017Est. completion: Apr 201824 patients
Phase 1Completed
NCT03130179Johnson & JohnsonNicorette Strongmint lozenge 4 mg

A Bioequivalence Study Between Two Nicotine Replacement Therapies in Adult Healthy Smokers Motivated to Quit.

Start: Mar 2017Est. completion: Jun 2017244 patients
Phase 1Completed

An Exploratory Study Comparing Two Nicotine Inhalers

Start: Nov 2011Est. completion: Dec 201136 patients
Phase 1Completed

Multiple-dose Nicotine Pharmacokinetics With Three Oral Nicotine Replacement Products

Start: Feb 2011Est. completion: Jun 201150 patients
Phase 1Completed

Financial Incentives for Smoking Treatment

Start: Jul 2015Est. completion: May 2019182 patients
N/ACompleted

"EASY EFFECTIVE SMOKELESS" With NICORETTE®

Start: Apr 2011Est. completion: Oct 2012184 patients
N/ACompleted

Nicotine Pharmacodynamics With a New Oral Nicotine Replacement Therapy and Nicotine Gum

Start: Apr 2011Est. completion: Jul 2011346 patients
N/ACompleted
NCT01234896Johnson & JohnsonNicotine Medicated Gum

Single-dose Nicotine Pharmacokinetics With Four Oral Nicotine Replacement Products

Start: Oct 2010Est. completion: Dec 201044 patients
N/ACompleted

Bioequivalence Between an Oral Nicotine Replacement Product and Nicorette® Gum

Start: Dec 2009Est. completion: May 201076 patients
N/ACompleted

Comparative Pharmacokinetic Study of New Oral Nicotine Replacement Therapy Products.

Start: Aug 2009Est. completion: Jan 2010104 patients
N/ACompleted

Single-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement Product

Start: Mar 2009Est. completion: Jun 200945 patients
N/ACompleted

Multiple-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement Product.

Start: Jan 2009Est. completion: Apr 200940 patients
N/ACompleted

Pharmacokinetics With a New Oral Nicotine Replacement Product and Nicorette® Gum

Start: Nov 2008Est. completion: Jan 200919 patients
N/ACompleted

Bioequivalence Between Nicotine Replacement Products and Nicorette® Gum

Start: Sep 2008Est. completion: Dec 200888 patients
N/ACompleted

Bioequivalence Between Two New Oral Nicotine Replacement Therapy Products and Nicorette® Microtab

Start: Aug 2008Est. completion: Nov 200884 patients
N/ACompleted

Single-dose Nicotine Pharmacokinetics With Three Oral Nicotine Replacement Products. A Study in Healthy Smokers.

Start: May 2008Est. completion: Jun 200824 patients
N/ACompleted

Pharmacokinetics With Two New Oral Nicotine Replacement Products and Nicorette® Gum

Start: Mar 2008Est. completion: May 200828 patients
N/ACompleted

Single-dose Pharmacokinetics of Oral Nicotine Replacement Products

Start: Sep 2007Est. completion: Oct 200740 patients
N/ACompleted
NCT01238627Johnson & JohnsonNicotine Sublingual Tablet Mint

Bioequivalence Between Two Oral Nicotine Sublingual Tablets, 2 mg and 4 mg

Start: Sep 2007Est. completion: Nov 200740 patients
N/ACompleted

A Study on the Effects of Two Nicotine Replacement Products on Tooth Staining

Start: Jul 2005Est. completion: Nov 2005200 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
1 companies competing in this space