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Tinnitus

5
Pipeline Programs
18
Companies
19
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
3
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

17 companies ranked by most advanced pipeline stage

Combined Therapeutics
1 program
1
DexamethasonePhase 41 trial
Active Trials
NCT04798391Unknown264Est. May 2021
Supernus Pharmaceuticals
1 program
1
BrexanolonePhase 21 trial
Active Trials
NCT05645432Completed10Est. Nov 2023
Bayer
BayerLEVERKUSEN, Germany
1 program
1
LevitraPhase 21 trial
Active Trials
NCT00666809Completed43Est. May 2007
ViiV Healthcare
ViiV HealthcareNC - Durham
1 program
1
VestipitantPhase 2
Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
1 program
1
AcamprosatePhase 11 trial
Active Trials
NCT00596531Completed154Est. Nov 2013
Neuromod Devices
Neuromod DevicesIreland - Dublin
4 programs
LenireN/A1 trial
Lenire bimodal stimulation deviceN/A1 trial
PS1N/A1 trial
PS1-PS4N/A1 trial
Active Trials
NCT05227365Completed112Est. Oct 2022
NCT05518682Completed26Est. Feb 2025
NCT02669069Completed326Est. Jan 2019
+1 more trials
Cochlear
CochlearAustralia - Macquarie Park
2 programs
Tinnitus Implant SystemN/A1 trial
Tinnitus maskingN/A1 trial
Active Trials
NCT06641999Recruiting16Est. Apr 2026
NCT02794623Completed12Est. Jun 2018
Otsuka
OtsukaJapan - Tokushima
1 program
CilostazolN/A1 trial
Active Trials
NCT01378650Completed50Est. Jun 2013
Soterix Medical
Soterix MedicalNJ - Woodbridge
1 program
Compensatory auditory stimulationN/A1 trial
Active Trials
NCT02648542Completed17Est. Jul 2014
Providence Therapeutics
1 program
Hericium honey bolusN/A1 trial
Active Trials
NCT03632512Unknown80Est. Jun 2020
Otolith Labs
Otolith LabsDC - Washington
1 program
OtobandN/A1 trial
Active Trials
NCT04787653Unknown40Est. Feb 2024
Novartis
NovartisBASEL, Switzerland
1 program
Tinnitus Measured by MEG and Synchronous Neural Interaction™ Test: Template DevelopmentN/A
Sandoz
SandozAustria - Kundl
1 program
Tinnitus Measured by MEG and Synchronous Neural Interaction™ Test: Template DevelopmentN/A1 trial
Active Trials
NCT01185990Unknown45Est. Aug 2011
MicroTransponder
MicroTransponderTX - Austin
1 program
VNS TreatmentN/A1 trial
Active Trials
NCT01962558Completed30Est. May 2016
Coordination Pharmaceuticals
1 program
Virtual RealityN/A1 trial
Active Trials
NCT04987502Completed120Est. May 2024
Biocorp
BiocorpFrance - Issoire
1 program
fMRI NeurofeedbackN/A1 trial
Active Trials
NCT05737888Completed85Est. Mar 2023
BrainsWay
BrainsWayJerusalem, Israel
1 program
Deep Transcranial Magnetic StimulationPHASE_21 trial
Active Trials
NCT02053961Withdrawn0Est. Jan 2016

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Combined TherapeuticsDexamethasone
Supernus PharmaceuticalsBrexanolone
BrainsWayDeep Transcranial Magnetic Stimulation
BayerLevitra
Oregon TherapeuticsAcamprosate
CochlearTinnitus Implant System
Neuromod DevicesLenire bimodal stimulation device
Coordination PharmaceuticalsVirtual Reality
Neuromod DevicesLenire
Otolith LabsOtoband
Providence TherapeuticsHericium honey bolus
Neuromod DevicesPS1-PS4
BiocorpfMRI Neurofeedback
Neuromod DevicesPS1
CochlearTinnitus masking

Showing 15 of 19 trials with date data

Clinical Trials (19)

Total enrollment: 1,621 patients across 19 trials

NCT04798391Combined TherapeuticsDexamethasone

Effectiveness of Intratympanic Dexamethasone With Ligmocaine for Alleviation of Tinnitus

Start: Mar 2021Est. completion: May 2021264 patients
Phase 4Unknown
NCT05645432Supernus PharmaceuticalsBrexanolone

An Open-Label Study Evaluating Brexanolone in Adults With Tinnitus

Start: May 2023Est. completion: Nov 202310 patients
Phase 2Completed
NCT02053961BrainsWayDeep Transcranial Magnetic Stimulation

Deep TMS of the Left Auditory Cortex Using the HMCIPCC Coil, in the Treatment of Patients With Tinnitus.

Start: Jan 2014Est. completion: Jan 20160
Phase 2Withdrawn
NCT00666809BayerLevitra

Vardenafil in Tinnitus

Start: Oct 2006Est. completion: May 200743 patients
Phase 2Completed
NCT00596531Oregon TherapeuticsAcamprosate

Clinical Trial of Acamprosate for Tinnitus

Start: Jan 2008Est. completion: Nov 2013154 patients
Phase 1Completed
NCT06641999CochlearTinnitus Implant System

Evaluating How a Tinnitus Implant Affects Tinnitus Loudness in Adults With Chronic Tinnitus and Varying Levels of Hearing Loss

Start: Jun 2025Est. completion: Apr 202616 patients
N/ARecruiting
NCT05518682Neuromod DevicesLenire bimodal stimulation device

Assessment of Bimodal Stimulation Device Compliance and Satisfaction in Individuals With Tinnitus

Start: Sep 2022Est. completion: Feb 202526 patients
N/ACompleted
NCT04987502Coordination PharmaceuticalsVirtual Reality

Virtual Reality and Subjective Tinnitus

Start: Sep 2022Est. completion: May 2024120 patients
N/ACompleted
NCT05227365Neuromod DevicesLenire

Treatment Evaluation of Neuromodulation for Tinnitus - Stage A3

Start: Mar 2022Est. completion: Oct 2022112 patients
N/ACompleted
NCT04787653Otolith LabsOtoband

Evaluation of the OtoBand as a Treatment to Reduce the Perceived Loudness of Tinnitus

Start: Mar 2021Est. completion: Feb 202440 patients
N/AUnknown
NCT03632512Providence TherapeuticsHericium honey bolus

Effect of Hericium Erinaceus on Clinical Patients With Hearing Impairment

Start: May 2018Est. completion: Jun 202080 patients
N/AUnknown
NCT03530306Neuromod DevicesPS1-PS4

Treatment Evaluation of Neuromodulation for Tinnitus - Stage A2

Start: Mar 2018Est. completion: Jul 2019191 patients
N/ACompleted
NCT05737888BiocorpfMRI Neurofeedback

Physiological Regulation of Chronic Tinnitus

Start: Feb 2017Est. completion: Mar 202385 patients
N/ACompleted
NCT02669069Neuromod DevicesPS1

Treatment Evaluation of Neuromodulation for Tinnitus (TENT-A)

Start: Jun 2016Est. completion: Jan 2019326 patients
N/ACompleted
NCT02794623CochlearTinnitus masking

Tinnitus Suppression for Cochlear Implant Recipients

Start: Oct 2014Est. completion: Jun 201812 patients
N/ACompleted
NCT01962558MicroTransponderVNS Treatment

Vagus Nerve Stimulation (VNS) Paired With Tones for Tinnitus

Start: Feb 2014Est. completion: May 201630 patients
N/ACompleted
NCT02648542Soterix MedicalCompensatory auditory stimulation

The Effects of Compensatory Auditory Stimulation and Transcranial Direct Current Stimulation on Tinnitus Perception

Start: Mar 2013Est. completion: Jul 201417 patients
N/ACompleted
NCT01378650OtsukaCilostazol

A Study on the Effect of Cilostazol in Patients With Chronic Tinnitus

Start: Jul 2011Est. completion: Jun 201350 patients
N/ACompleted
NCT01185990SandozTinnitus Measured by MEG and Synchronous Neural Interaction™ Test: Template Development

Tinnitus Measured by MEG and Synchronous Neural Interaction™ Test: Template Development

Start: Aug 2010Est. completion: Aug 201145 patients
N/AUnknown

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 1,621 patients
18 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.