T2DM

6
Pipeline Programs
3
Companies
5
Clinical Trials
1 recruiting
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
4
1
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Peptide
2100%
+ 3 programs with unclassified modality

On Market (1)

Approved therapies currently available

U
METFORMIN HYDROCHLORIDEApproved
metformin
Unknown Company
oral2018

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Celltrion
CelltrionKorea - Incheon
2 programs
2
CT-L03 Group 1Phase 31 trial
MetforminPhase 31 trial
Active Trials
NCT06571591Active Not Recruiting582Est. May 2026
NCT07093476Recruiting171Est. Apr 2027
Sciwind Biosciences
Sciwind BiosciencesChina - Hangzhou
2 programs
2
EcnoglutidePhase 3Peptide1 trial
Ecnoglutide high dosagePhase 3Peptide1 trial
Active Trials
NCT05680155CompletedEst. Oct 2024
NCT05680129CompletedEst. Oct 2024
Chipscreen Biosciences
Chipscreen BiosciencesChina - Shenzhen
1 program
1
ChiglitazarPhase 11 trial
Active Trials
NCT05681273CompletedEst. Mar 2023

Trial Timeline

Clinical trial activity over time

2022
2023
2024
2025
2026
2027
CelltrionMetformin
CelltrionCT-L03 Group 1
Sciwind BiosciencesEcnoglutide high dosage
Sciwind BiosciencesEcnoglutide
Chipscreen BiosciencesChiglitazar

Clinical Trials (5)

Total enrollment: 753 patients across 5 trials

Efficacy and Safety of Add-On Therapy With Empagliflozin in Patients With Type 2 Diabetes on a Background of Alogliptin and Metformin

Start: Jul 2025Est. completion: Apr 2027171 patients
Phase 3Recruiting
NCT06571591CelltrionCT-L03 Group 1

Efficacy and Safety of Pioglitazone Combination Therapy in Type 2 Diabetes Patients on a Background of Empagliflozin With Metformin

Start: Aug 2024Est. completion: May 2026582 patients
Phase 3Active Not Recruiting
NCT05680129Sciwind BiosciencesEcnoglutide high dosage

A Phase 3 Study to Evaluate the Efficacy of XW003 Compared With Dulaglutide in Participants With T2DM

Start: Jan 2023Est. completion: Oct 2024
Phase 3Completed

A Phase 3 Study to Evaluate the Efficacy of XW003 Compared With Placebo in T2DM Patients

Start: Dec 2022Est. completion: Oct 2024
Phase 3Completed

Drug-Drug Interaction Study of Chiglitazar in Healthy Subjects.

Start: Feb 2023Est. completion: Mar 2023
Phase 1Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

4 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 753 patients
3 companies competing in this space