Skip to main content

Substance Use Disorders

0
Pipeline Programs
9
Companies
16
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

7 companies ranked by most advanced pipeline stage

Angeles Therapeutics
Angeles TherapeuticsCA - Los Angeles
5 programs
DARTNAN/A1 trial
PURPOSEN/A1 trial
PrEP navigation + text messagingN/A1 trial
SBIRTN/A1 trial
Substance Misuse Assistance Response TeamN/A1 trial
Active Trials
NCT01356667Terminated10Est. Aug 2012
NCT02629068Withdrawn0Est. Aug 2018
NCT05934877Terminated152Est. Mar 2025
+2 more trials
Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
4 programs
Group Community Reinforcement Training for ParentsN/A1 trial
Peer Recovery Support-Delivered Dropout Prevention enhancementN/A1 trial
RRFTN/A
Standard Contingency ManagementN/A1 trial
Active Trials
NCT01829789Completed60Est. Mar 2016
NCT05374395Active Not Recruiting11Est. Feb 2027
NCT03249350Completed129Est. Jul 2024
Human BioSciences
Human BioSciencesWV - Martinsburg
2 programs
Going Places: School program to prevent problem behaviorN/A1 trial
Parent-Child Assistance ProgramN/A1 trial
Active Trials
NCT00062959Completed2,768Est. Jun 2000
NCT05534568Recruiting200Est. Nov 2026
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
2 programs
Heart rate variability biofeedback + treatment as usualN/A1 trial
RRFTN/A1 trial
Active Trials
NCT05454657Completed120Est. Jul 2025
NCT05384223Active Not Recruiting212Est. Feb 2027
Integrated Biosciences
Integrated BiosciencesCA - San Carlos
1 program
Adherence to ASAM protocolsN/A1 trial
Active Trials
NCT03486028Completed991Est. Oct 2019
Temple Therapeutics
Temple TherapeuticsNetherlands - Geleen
1 program
CoreN/A1 trial
Active Trials
NCT02672150Completed839Est. Jun 2019
Clear Scientific
Clear ScientificMA - Cambridge
1 program
CS-1103PHASE_12 trials
Active Trials
NCT07459166Not Yet Recruiting16Est. Oct 2026
NCT06316973Completed32Est. Jun 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Clear ScientificCS-1103
Clear ScientificCS-1103
Angeles TherapeuticsSubstance Misuse Assistance Response Team
Oregon TherapeuticsPeer Recovery Support-Delivered Dropout Prevention enhancement
Angeles TherapeuticsPrEP navigation + text messaging
Colorado TherapeuticsHeart rate variability biofeedback + treatment as usual
Human BioSciencesParent-Child Assistance Program
Colorado TherapeuticsRRFT
Integrated BiosciencesAdherence to ASAM protocols
Oregon TherapeuticsStandard Contingency Management
Angeles TherapeuticsPURPOSE
Temple TherapeuticsCore
Oregon TherapeuticsGroup Community Reinforcement Training for Parents
Angeles TherapeuticsSBIRT
Angeles TherapeuticsDARTNA

Showing 15 of 16 trials with date data

Clinical Trials (16)

Total enrollment: 7,020 patients across 16 trials

A Phase 2 Safety, Tolerability, PK, and Efficacy Study of CS-1103 Following Fentanyl Challenge With Naloxone Blockade

Start: Apr 2026Est. completion: Oct 202616 patients
Phase 2Not Yet Recruiting

A Clinical Study to Evaluate the Safety of CS-1103 in Healthy Participants

Start: Feb 2024Est. completion: Jun 202432 patients
Phase 1Completed
NCT06320015Angeles TherapeuticsSubstance Misuse Assistance Response Team

Emergency Medicine Peer Outreach Worker Engagement for Recovery

Start: Jul 2024Est. completion: Oct 2026400 patients
N/ARecruiting
NCT05374395Oregon TherapeuticsPeer Recovery Support-Delivered Dropout Prevention enhancement

Enhancing Substance Use Treatment Services to Decrease Dropout and Improve Outpatient Treatment Utilization in Emerging Adults

Start: Jul 2023Est. completion: Feb 202711 patients
N/AActive Not Recruiting
NCT05934877Angeles TherapeuticsPrEP navigation + text messaging

ASK-PrEP (Assistance Services Knowledge-PrEP)

Start: May 2023Est. completion: Mar 2025152 patients
N/ATerminated
NCT05454657Colorado TherapeuticsHeart rate variability biofeedback + treatment as usual

Heart Rate Variability Biofeedback for Substance Use Disorder: A Randomized Clinical Trial

Start: Jan 2023Est. completion: Jul 2025120 patients
N/ACompleted
NCT05534568Human BioSciencesParent-Child Assistance Program

The Oklahoma Parent-Child Assistance Program

Start: Nov 2022Est. completion: Nov 2026200 patients
N/ARecruiting

Evaluation of RRFT for Co-occurring SUD and PTSD Among Teens

Start: Oct 2022Est. completion: Feb 2027212 patients
N/AActive Not Recruiting
NCT03486028Integrated BiosciencesAdherence to ASAM protocols

Patient Centered Assessment and Substance Use Disorder Treatment Study (PCAST)

Start: Jul 2018Est. completion: Oct 2019991 patients
N/ACompleted
NCT03249350Oregon TherapeuticsStandard Contingency Management

Enhancing Adolescent Substance Abuse Treatment

Start: Apr 2018Est. completion: Jul 2024129 patients
N/ACompleted

PURPOSE: A Social Media Intervention for Parent Support

Start: Oct 2016Est. completion: Aug 20180
N/AWithdrawn

Juvenile Justice Translational Research on Interventions for Adolescents in the Legal System

Start: Jul 2013Est. completion: Jun 2019839 patients
N/ACompleted
NCT01829789Oregon TherapeuticsGroup Community Reinforcement Training for Parents

Individual vs. Group Community Reinforcement Training to Help Parents of Substance-using Treatment-refusing Youth

Start: Apr 2013Est. completion: Mar 201660 patients
N/ACompleted

Screening, Brief Intervention and Referral to Treatment for Substance Abuse in Mental Health Treatment Settings

Start: Mar 2013Est. completion: Jun 20181,080 patients
N/ACompleted

Drum-Assisted Therapy for Native Americans

Start: Sep 2010Est. completion: Aug 201210 patients
N/ATerminated
NCT00062959Human BioSciencesGoing Places: School program to prevent problem behavior

Preventing Problem Behavior Among Middle School Students

Start: Jun 1994Est. completion: Jun 20002,768 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 actively recruiting trials targeting 7,020 patients
9 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.