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Subarachnoid Hemorrhage

8
Pipeline Programs
10
Companies
11
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
2
3
1
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

10 companies ranked by most advanced pipeline stage

Alliance Pharmaceuticals
1 program
1
IL-1RaPhase 31 trial
Active Trials
NCT03249207Unknown612Est. Sep 2024
Defence Therapeutics
Defence TherapeuticsBC - Vancouver
1 program
1
KetaminePhase 2/31 trial
Active Trials
NCT02636218Completed9Est. Nov 2023
Hope Pharmaceuticals
Hope PharmaceuticalsAZ - Scottsdale
2 programs
2
Sodium NitritePhase 21 trial
Sodium nitritePhase 21 trial
Active Trials
NCT02176837Terminated6Est. Jan 2017
NCT00873015Completed19Est. Aug 2012
NoNO
NoNOON - Toronto
1 program
1
NA-1Phase 21 trial
Active Trials
NCT02056574Withdrawn0Est. Apr 2020
Orion Pharma
Orion PharmaUK - Reading
1 program
1
Dexmedetomidine infusionPhase 1/2
Orion
OrionUK - Cambridge
1 program
1
Dexmedetomidine infusionPhase 1/21 trial
Active Trials
NCT01664520Completed10Est. Dec 2016
Shield Therapeutics
Shield TherapeuticsMA - Wellesley
1 program
1
desferrioxaminePhase 11 trial
Active Trials
NCT02216513Terminated2Est. Jul 2015
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
2 programs
Pharmacokinetic modelingN/A1 trial
Physical TherapyN/A1 trial
Active Trials
NCT02866877Completed15Est. Mar 2021
NCT02675985Completed30Est. Nov 2017
B. Braun
B. BraunGermany - Melsungen
1 program
Nimodipine pump infusionN/A1 trial
Active Trials
NCT04309708Completed300Est. Sep 2019
Medtronic
MedtronicNJ - Phillipsburg
1 program
Ventriculostomy in Subarachnoid Hemorrhage (SAH): Intracranial Pressure (ICP) Open or Not?N/A1 trial
Active Trials
NCT01169454Terminated60Est. Sep 2012

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Alliance PharmaceuticalsIL-1Ra
Defence TherapeuticsKetamine
NoNONA-1
Hope PharmaceuticalsSodium Nitrite
Hope PharmaceuticalsSodium nitrite
OrionDexmedetomidine infusion
Shield Therapeuticsdesferrioxamine
B. BraunNimodipine pump infusion
Colorado TherapeuticsPhysical Therapy
Colorado TherapeuticsPharmacokinetic modeling
MedtronicVentriculostomy in Subarachnoid Hemorrhage (SAH): Intracranial Pressure (ICP) Open or Not?

Clinical Trials (11)

Total enrollment: 1,063 patients across 11 trials

NCT03249207Alliance PharmaceuticalsIL-1Ra

SC IL-1Ra in SAH - Phase III Trial (SCIL)

Start: Oct 2018Est. completion: Sep 2024612 patients
Phase 3Unknown
NCT02636218Defence TherapeuticsKetamine

Ketamine Infusion in Neurologic Deficit

Start: Jan 2016Est. completion: Nov 20239 patients
Phase 2/3Completed
NCT02056574NoNONA-1

Safety and Efficacy Study of a Single Dose of NA-1 in Patients Undergoing Endovascular Repair of Ruptured Aneurysms

Start: Nov 2015Est. completion: Apr 20200
Phase 2Withdrawn
NCT02176837Hope PharmaceuticalsSodium Nitrite

Intravenous Nitrite Infusion for Reversal of Cerebral Vasospasm After Subarachnoid Hemorrhage

Start: Jun 2014Est. completion: Jan 20176 patients
Phase 2Terminated
NCT00873015Hope PharmaceuticalsSodium nitrite

Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm

Start: Apr 2010Est. completion: Aug 201219 patients
Phase 2Completed
NCT01664520OrionDexmedetomidine infusion

Dexmedetomidine and Subarachnoid Haemorrhage

Start: Jun 2013Est. completion: Dec 201610 patients
Phase 1/2Completed
NCT02216513Shield Therapeuticsdesferrioxamine

Deferoxamine to Prevent Delayed Cerebral Ischemia After Subarachnoid Hemorrhage

Start: Sep 2014Est. completion: Jul 20152 patients
Phase 1Terminated
NCT04309708B. BraunNimodipine pump infusion

Efficacy and Safety Assessment for a New UV-protected Pump Infusion Line in Intravenous Infusion Therapy

Start: May 2018Est. completion: Sep 2019300 patients
N/ACompleted
NCT02675985Colorado TherapeuticsPhysical Therapy

Early Intensive Physical Therapy in Subarachnoid Hemorrhage

Start: Aug 2016Est. completion: Nov 201730 patients
N/ACompleted
NCT02866877Colorado TherapeuticsPharmacokinetic modeling

Effects of Augmented Renal Clearance on Pharmacokinetic and Pharmacodynamic Properties of Levetiracetam in Subarachnoid Hemorrhage

Start: Jan 2016Est. completion: Mar 202115 patients
N/ACompleted
NCT01169454MedtronicVentriculostomy in Subarachnoid Hemorrhage (SAH): Intracranial Pressure (ICP) Open or Not?

Ventriculostomy in Subarachnoid Hemorrhage (SAH): Intracranial Pressure (ICP) Open or Not?

Start: Mar 2009Est. completion: Sep 201260 patients
N/ATerminated

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs, potential near-term approvals
10 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.