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Stomach Ulcer

6
Pipeline Programs
6
Companies
7
Clinical Trials
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
2
0
0
3
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 7 programs with unclassified modality

On Market (1)

Approved therapies currently available

Takeda
PREVACIDApproved
lansoprazole
Takeda
Proton Pump Inhibitor [EPC]oral1995
11M Part D

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Otsuka
OtsukaJapan - Tokushima
2 programs
2
RebamipidePhase 41 trial
RebamipidePhase 41 trial
Active Trials
NCT00233389Completed301Est. Sep 2005
NCT00272467Completed132Est. Apr 2008
Takeda
TakedaTOKYO, Japan
1 program
1
PREVACID(Lansoprazole)PHASE_3Small Molecule1 trial
Active Trials
NCT00787254Completed366Est. May 2009
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
1
MK0782Phase 2
MSD
MSDIreland - Ballydine
1 program
1
MK0782Phase 21 trial
Active Trials
NCT00543868Completed462Est. Aug 2004
Biocorp
BiocorpFrance - Issoire
1 program
1
CDFR0209Phase 11 trial
Active Trials
NCT02710994Completed30Est. Mar 2015
Eisai
EisaiChina - Liaoning
2 programs
ParietN/A1 trial
E0671PHASE_41 trial
Active Trials
NCT05208268Completed676Est. Sep 2022
NCT00125736Completed520Est. Apr 2007

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
EisaiE0671
OtsukaRebamipide
OtsukaRebamipide
TakedaLansoprazole
MSDMK0782
BiocorpCDFR0209
EisaiPariet

Clinical Trials (7)

Total enrollment: 2,487 patients across 7 trials

A Double-blind, Comparative Study in Patients With Gastric Ulcer to Evaluate the Efficacy of Combination Use of E0671 and Rabeprazole Sodium

Start: Aug 2005Est. completion: Apr 2007520 patients
Phase 4Completed

Healing Effects of Rebamipide and Omeprazole in Helicobacter Pylori-positive Gastric Ulcer After Eradication Therapy

Start: Jul 2005Est. completion: Apr 2008132 patients
Phase 4Completed

Post-marketing Clinical Study of Rebamipide in Patients With Gastric Ulcer

Start: Apr 2004Est. completion: Sep 2005301 patients
Phase 4Completed
NCT00787254TakedaLansoprazole

Efficacy and Safety of Lansoprazole on Gastric and Duodenal Ulcers in Patients Taking Nonsteroidal Anti-Inflammatory Drugs

Start: Apr 2007Est. completion: May 2009366 patients
Phase 3Completed

MK0782 + Low-Dose Aspirin 7-Day Erosion Endoscopy Study (0782-001)

Start: Jun 2004Est. completion: Aug 2004462 patients
Phase 2Completed

Pharmacodynamics and Safety of CDFR0209

Start: May 2014Est. completion: Mar 201530 patients
Phase 1Completed

A Study of Pariet to Prevent Gastric and Duodenal Ulcer Associated With Low-aspirin in Korean Participants With a History of Gastric and Duodenal Ulcer

Start: Jul 2020Est. completion: Sep 2022676 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

6 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.