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Stiff-Person Syndrome

1
Pipeline Programs
2
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Kyverna Therapeutics
Kyverna TherapeuticsCA - Emeryville
1 program
1
Standard lymphodepletion regimenPhase 21 trial
Active Trials
NCT06588491Active Not Recruiting25Est. Dec 2026
Grifols
GrifolsNEW YORK, NY
1 program
Intravenous Immunoglobulins, HumanPHASE_31 trial
Active Trials
NCT03749096Withdrawn0Est. Apr 2019

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
GrifolsIntravenous Immunoglobulins, Human
Kyverna TherapeuticsStandard lymphodepletion regimen

Clinical Trials (2)

Total enrollment: 25 patients across 2 trials

NCT03749096GrifolsIntravenous Immunoglobulins, Human

Randomized Placebo Controlled Trial of IVIg in Glycine Receptor Antibody Positive Stiff-person Syndrome

Start: Dec 2018Est. completion: Apr 20190
Phase 3Withdrawn
NCT06588491Kyverna TherapeuticsStandard lymphodepletion regimen

KYSA-8: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Treatment Refractory Stiff Person Syndrome

Start: Sep 2024Est. completion: Dec 202625 patients
Phase 2Active Not Recruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.