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STEMI - ST Elevation Myocardial Infarction

3
Pipeline Programs
6
Companies
8
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
1
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Green Valley Pharmaceuticals
1 program
1
Normal salinePhase 41 trial
Active Trials
NCT03045562Unknown536Est. Dec 2018
Medical Developments International
1 program
1
MethoxyfluranePhase 31 trial
Active Trials
NCT07445737Not Yet Recruiting700Est. Jun 2029
CorFlow Therapeutics
CorFlow TherapeuticsSwitzerland - Baar
1 program
1
CorFlow Controlled Flow Infusion System - CoFI™Phase 11 trial
Active Trials
NCT03654573Completed73Est. Dec 2024
Miracor Medical
Miracor MedicalBelgium - Awans
3 programs
PiCSON/A1 trial
PiCSO Impulse SystemN/A1 trial
PiCSO Impulse SystemN/A1 trial
Active Trials
NCT04566289Withdrawn0Est. Dec 2027
NCT05497011Withdrawn0Est. Jun 2028
NCT04958421Terminated25Est. Feb 2023
Intratech Medical
Intratech MedicalIsrael - Kibbutz Shefayim
1 program
Booster Balloon CatheterN/A1 trial
Active Trials
NCT05557019Unknown20Est. Oct 2023
Genentech
GenentechCA - Oceanside
1 program
TelehealthN/A1 trial
Active Trials
NCT06945900Completed11Est. Dec 2025

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
Green Valley PharmaceuticalsNormal saline
Medical Developments InternationalMethoxyflurane
CorFlow TherapeuticsCorFlow Controlled Flow Infusion System - CoFI™
GenentechTelehealth
Miracor MedicalPiCSO Impulse System
Miracor MedicalPiCSO
Intratech MedicalBooster Balloon Catheter
Miracor MedicalPiCSO Impulse System

Clinical Trials (8)

Total enrollment: 1,365 patients across 8 trials

Effects of Salvianolate Injection on Myocardial Microcirculation in Patients With Acute STEMI After Primary PCI

Start: Jan 2017Est. completion: Dec 2018536 patients
Phase 4Unknown

Use of the Methoxyflurane as Pain-killer in the Prehospital Management of Acute Myocardial Infarction

Start: Jun 2026Est. completion: Jun 2029700 patients
Phase 3Not Yet Recruiting
NCT03654573CorFlow TherapeuticsCorFlow Controlled Flow Infusion System - CoFI™

The MOCA I Study - Microvascular Obstruction with CoFI™ System Assessment

Start: Jun 2019Est. completion: Dec 202473 patients
Phase 1Completed

Emergency Medical Services (EMS) Telehealth to Speed STEMI Reperfusion

Start: Jun 2025Est. completion: Dec 202511 patients
N/ACompleted
NCT05497011Miracor MedicalPiCSO Impulse System

A Study to Evaluate the Safety and Efficacy of PiCSO in Anterior STEMI Patients

Start: Mar 2023Est. completion: Jun 20280
N/AWithdrawn

Observational Registry to Evaluate Real World Usage of PiCSO Impulse System in STEMI Patients as Part of Post-marketing Surveillance

Start: Oct 2022Est. completion: Dec 20270
N/AWithdrawn
NCT05557019Intratech MedicalBooster Balloon Catheter

Semi Occlusion of the Coronary Sinus as an Adjunct to PCI in STEMI Patients, FIH Clinical Study

Start: Sep 2022Est. completion: Oct 202320 patients
N/AUnknown
NCT04958421Miracor MedicalPiCSO Impulse System

A Study to Evaluate Safety and Feasibility of PiCSO Therapy in Patients With ST Elevation Inferior Wall Myocardial Infarction.

Start: Feb 2022Est. completion: Feb 202325 patients
N/ATerminated

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs, potential near-term approvals
6 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.