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Sprains and Strains

2
Pipeline Programs
4
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
2
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

MSD
MSDIreland - Ballydine
1 program
1
etoricoxib 90mg 14 daysPhase 41 trial
Active Trials
NCT00525993Unknown50Est. Sep 2009
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
1
etoricoxib 90mg 14 daysPhase 4
Ortho Development
1 program
tramadol HCl + acetaminophen; hydrocodone bitartrate + acetaminophen; placeboPHASE_31 trial
Active Trials
NCT00236535Completed603Est. Oct 2004
Johnson & Johnson
Johnson & JohnsonNEW BRUNSWICK, NJ
1 program
acetaminophenPHASE_41 trial
Active Trials
NCT00261560Completed260Est. Feb 2004

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Johnson & Johnsonacetaminophen
MSDetoricoxib 90mg 14 days
Ortho Developmenttramadol HCl + acetaminophen; hydrocodone bitartrate + acetaminophen; placebo

Clinical Trials (3)

Total enrollment: 913 patients across 3 trials

A Safety and Effectiveness Study of Acetaminophen Extended Release (3900 mg/Day) and Ibuprofen (1200 mg/Day) in the Treatment of Pain Associated With Ankle Sprains.

Est. completion: Feb 2004260 patients
Phase 4Completed
NCT00525993MSDetoricoxib 90mg 14 days

Efficacy and Safety of Etoricoxib in Acute Ankle Sprain: A Double-Blind Comparative Study Among 2 Treatments Protocols

Start: Dec 2008Est. completion: Sep 200950 patients
Phase 4Unknown
NCT00236535Ortho Developmenttramadol HCl + acetaminophen; hydrocodone bitartrate + acetaminophen; placebo

A Study of the Efficacy and Safety of Tramadol HCl/Acetaminophen, Hydrocodone Bitartrate/Acetaminophen and Placebo in Patients With Pain From an Ankle Sprain With a Partial Torn Ligament

Start: Dec 2003Est. completion: Oct 2004603 patients
Phase 3Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.