Spondyloarthritis

2
Pipeline Programs
8
Companies
1
Clinical Trials
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
1
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1100%
+ 6 programs with unclassified modality

On Market (1)

Approved therapies currently available

Eli Lilly and Company
TALTZApproved
ixekizumab
Eli Lilly and Company
Interleukin-17A Antagonist [EPC]injection2016

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Eli Lilly and Company
Eli Lilly and CompanyINDIANAPOLIS, IN
2 programs
1
1
IxekizumabPhase 3Monoclonal Antibody1 trial
CLassification of Axial SpondyloarthritiS Inception CohortN/A
Active Trials
NCT02696798Completed316Est. May 2019
Pfizer
PfizerNEW YORK, NY
1 program
CLassification of Axial SpondyloarthritiS Inception CohortN/A
Novartis
NovartisBASEL, Switzerland
1 program
CLassification of Axial SpondyloarthritiS Inception CohortN/A
Amgen
AmgenTHOUSAND OAKS, CA
1 program
CLassification of Axial SpondyloarthritiS Inception CohortN/A
UP
UCB PharmaBelgium - Brussels
1 program
CLassification of Axial SpondyloarthritiS Inception CohortN/A
AbbVie
AbbVieNORTH CHICAGO, IL
1 program
CLassification of Axial SpondyloarthritiS Inception CohortN/A

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Eli Lilly and CompanyIxekizumab

Clinical Trials (1)

Total enrollment: 316 patients across 1 trials

A Study of Ixekizumab (LY2439821) in TNF Inhibitor Experienced Participants With Radiographic Axial Spondyloarthritis

Start: Apr 2016Est. completion: May 2019316 patients
Phase 3Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
8 companies competing in this space