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Spine Surgery

5
Pipeline Programs
8
Companies
6
Clinical Trials
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
5
Early DiscoveryClinical DevelopmentMarket

On Market (1)

Approved therapies currently available

Merck & Co.
BRIDIONApproved
sugammadex
Merck & Co.
intravenous2015

Competitive Landscape

8 companies ranked by most advanced pipeline stage

Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
2 programs
2
SugammadexPhase 4
sugammadexPhase 4
MSD
MSDIreland - Ballydine
2 programs
2
SugammadexPhase 41 trial
sugammadexPhase 41 trial
Active Trials
NCT05887375Enrolling By Invitation118Est. Jun 2026
NCT03112993Completed40Est. Aug 2018
Merck & Co.
Merck & Co.RAHWAY, NJ
1 program
1
sugammadexPHASE_4
Pfizer
PfizerNEW YORK, NY
1 program
DexmedetomidineN/A1 trial
Active Trials
NCT00494832Completed40Est. May 2010
Globus Medical
Globus MedicalAUDUBON, PA
1 program
NuvaMap O.R.N/A1 trial
Active Trials
NCT02606695Completed306Est. Dec 2020
NuVasive
NuVasiveCA - San Diego
1 program
NuvaMap O.R.N/A
Medtronic
MedtronicNJ - Phillipsburg
1 program
Solera™ MedtronicN/A1 trial
Active Trials
NCT02551302Unknown60Est. Dec 2017
Surgify Medical
Surgify MedicalFinland - Espoo
1 program
Surgify Safety BurrN/A1 trial
Active Trials
NCT05269836Completed22Est. Nov 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
MSDSugammadex
MSDsugammadex
Surgify MedicalSurgify Safety Burr
Globus MedicalNuvaMap O.R.
MedtronicSolera™ Medtronic
PfizerDexmedetomidine

Clinical Trials (6)

Total enrollment: 586 patients across 6 trials

NCT05887375MSDSugammadex

Sugammadex vs Neostigmine/Glycopyrrolate on Urinary Retention After Spine Surgery

Start: Aug 2023Est. completion: Jun 2026118 patients
Phase 4Enrolling By Invitation
NCT03112993MSDsugammadex

Speed of Recovery of Reversal of Neuromuscular Blockade in Geriatric Patients Undergoing Spine Surgery

Start: May 2017Est. completion: Aug 201840 patients
Phase 4Completed
NCT05269836Surgify MedicalSurgify Safety Burr

Use of Surgify Safety Burr in Hard Tissue Cutting, Head and Spine Area

Start: Mar 2022Est. completion: Nov 202222 patients
N/ACompleted

Comprehensive Spinal Alignment Planning Study

Start: Mar 2016Est. completion: Dec 2020306 patients
N/ACompleted
NCT02551302MedtronicSolera™ Medtronic

"Efficacy of Hybrid Systems ("Topping Off") Versus Rigid Spinal Fusion in Lumbar Fusion Surgery: A Dual-center, Prospective, Randomized Pilot Study ("CD Horizon BalanC")"

Start: Oct 2015Est. completion: Dec 201760 patients
N/AUnknown
NCT00494832PfizerDexmedetomidine

Influence of Dexmedetomidine on the Evoked Potentials During Spine Surgery

Start: Feb 2008Est. completion: May 201040 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

8 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.