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Sleep Deprivation

3
Pipeline Programs
8
Companies
13
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
1
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

7 companies ranked by most advanced pipeline stage

ViiV Healthcare
ViiV HealthcareNC - Durham
1 program
1
donepezilPhase 4
Pfizer
PfizerNEW YORK, NY
1 program
1
PregabalinPhase 31 trial
Active Trials
NCT00643136Completed17Est. Jun 2004
Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
3 programs
1
Tai ChiPhase 11 trial
No interventinonN/A1 trial
Sleep RestrictionN/A1 trial
Active Trials
NCT06452459Not Yet Recruiting10Est. Jul 2028
NCT05775627Recruiting20Est. Jun 2027
NCT00079664Completed100Est. Jul 2003
Philips
PhilipsNetherlands - Amsterdam
4 programs
Live ChatN/A1 trial
Philips SmartSleep Acoustic Stimulation DeviceN/A1 trial
PowerSleep StimN/A1 trial
PowerSleep StimN/A1 trial
Active Trials
NCT05066581Completed202Est. Nov 2022
NCT05309473Recruiting44Est. Oct 2026
NCT03162328Completed84Est. Nov 2017
+1 more trials
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
3 programs
Increased sleep durationN/A1 trial
Insufficient SleepN/A1 trial
Insufficient SleepN/A1 trial
Active Trials
NCT04214184Completed38Est. Dec 2025
NCT03747367Unknown50Est. Sep 2021
NCT03130803Completed12Est. Feb 2019
Human BioSciences
Human BioSciencesWV - Martinsburg
1 program
Parent Behavior Change InterventionN/A1 trial
Active Trials
NCT03926221Completed112Est. Aug 2020
Providence Therapeutics
1 program
Reduced work hour scheduleN/A1 trial
Active Trials
NCT00996320Completed22Est. Jun 2009

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
PfizerPregabalin
Oregon TherapeuticsTai Chi
Oregon TherapeuticsNo interventinon
Oregon TherapeuticsSleep Restriction
PhilipsPhilips SmartSleep Acoustic Stimulation Device
PhilipsLive Chat
Colorado TherapeuticsIncreased sleep duration
Human BioSciencesParent Behavior Change Intervention
PhilipsPowerSleep Stim
PhilipsPowerSleep Stim
Colorado TherapeuticsInsufficient Sleep
Colorado TherapeuticsInsufficient Sleep
Providence TherapeuticsReduced work hour schedule

Clinical Trials (13)

Total enrollment: 749 patients across 13 trials

A Study of Lyrica as Treatment for Sleep Problems in Patients With Sleep Problems and Seizures

Start: Nov 2002Est. completion: Jun 200417 patients
Phase 3Completed

Comparing Tai Chi Training to a Low-Stress Physical Activity to Enhance Sleep in Older Adults

Start: Sep 2001Est. completion: Jul 2003100 patients
Phase 1Completed

Glymphatic MRI Study

Start: Jul 2024Est. completion: Jul 202810 patients
N/ANot Yet Recruiting

Sleep and Metabolism

Start: Dec 2023Est. completion: Jun 202720 patients
N/ARecruiting
NCT05309473PhilipsPhilips SmartSleep Acoustic Stimulation Device

Acoustic Stimulation During Restricted Sleep After Sleep Deprivation

Start: Mar 2022Est. completion: Oct 202644 patients
N/ARecruiting

Vitoria Sleep Smart City: Interactive Intervention for Sleep Improvement

Start: Jun 2021Est. completion: Nov 2022202 patients
N/ACompleted
NCT04214184Colorado TherapeuticsIncreased sleep duration

Biomarkers of Increased Free Living Sleep Time

Start: Dec 2019Est. completion: Dec 202538 patients
N/ACompleted
NCT03926221Human BioSciencesParent Behavior Change Intervention

Parent-Adolescent Interpersonal Processes in the Science of Behavior Change

Start: Dec 2018Est. completion: Aug 2020112 patients
N/ACompleted
NCT03600194PhilipsPowerSleep Stim

Pilot Study Comparing the Effectiveness of Two Different Methods of Acoustic Stimulation

Start: Jun 2018Est. completion: Jul 201938 patients
N/ACompleted
NCT03162328PhilipsPowerSleep Stim

A Study of the Effectiveness and Efficacy of the PowerSleep Device

Start: Apr 2017Est. completion: Nov 201784 patients
N/ACompleted

Biomarkers of Insufficient Sleep and Sleepiness

Start: Jan 2017Est. completion: Feb 201912 patients
N/ACompleted

The Microbiome and Resilience to Sleep and Circadian Disruption

Start: Oct 2015Est. completion: Sep 202150 patients
N/AUnknown
NCT00996320Providence TherapeuticsReduced work hour schedule

Work Hour Reductions, Medical Errors, and Intern Well-Being at Providence St. Vincent Medical Center Intensive Care Unit

Start: Jun 2008Est. completion: Jun 200922 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs, potential near-term approvals
2 actively recruiting trials targeting 749 patients
8 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.