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Skin Diseases, Bacterial

5
Pipeline Programs
7
Companies
6
Clinical Trials
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
1
0
0
2
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
3100%
+ 5 programs with unclassified modality

On Market (1)

Approved therapies currently available

Pfizer
TYGACILApproved
tigecycline
Pfizer
Tetracycline-class Antibacterial [EPC]intravenous2005
85K Part D

Competitive Landscape

7 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
2 programs
1
TigecyclinePhase 4Small Molecule1 trial
LinezolidN/A1 trial
Active Trials
NCT01619410Terminated25Est. Dec 2016
NCT00368537Completed550Est. Sep 2008
MicuRx Pharmaceuticals
MicuRx PharmaceuticalsCA - Foster City
1 program
1
contezolid acefosamilPhase 21 trial
Active Trials
NCT03747497Completed196Est. Mar 2019
MSD
MSDIreland - Ballydine
1 program
1
midazolamPhase 1
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
1
midazolamPhase 11 trial
Active Trials
NCT02477514Completed18Est. Aug 2015
Bayer
BayerLEVERKUSEN, Germany
1 program
MoxifloxacinN/ASmall Molecule1 trial
Active Trials
NCT00997997Completed6,127Est. Dec 2008
Merck & Co.
Merck & Co.RAHWAY, NJ
1 program
midazolamPHASE_1
Ortho Development
1 program
levofloxacinPHASE_3Small Molecule1 trial
Active Trials
NCT00249197Completed413Est. Jul 1998

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
PfizerTigecycline
Ortho Developmentlevofloxacin
MicuRx Pharmaceuticalscontezolid acefosamil
Sharp Therapeuticsmidazolam
PfizerLinezolid
BayerMoxifloxacin

Clinical Trials (6)

Total enrollment: 7,329 patients across 6 trials

Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin Infections

Start: Sep 2006Est. completion: Sep 2008550 patients
Phase 4Completed

A Study of the Safety and Effectiveness of Levofloxacin Compared to Ticarcillin/Clavulanate Alone or Followed by Amoxicillin/Clavulanate in the Treatment of Complicated Skin Infections

Start: Jan 1997Est. completion: Jul 1998413 patients
Phase 3Completed

Contezolid Acefosamil Versus Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infection

Start: Nov 2018Est. completion: Mar 2019196 patients
Phase 2Completed

A Study to Evaluate the Effects of Tedizolid Phosphate on the Pharmacokinetics and Safety of Midazolam and Rosuvastatin (MK-1986-004)

Start: Jun 2015Est. completion: Aug 201518 patients
Phase 1Completed

Asymptomatic Colonization With S. Aureus After Therapy With Linezolid or Clindamycin for Acute Skin Infections

Start: Jan 2012Est. completion: Dec 201625 patients
N/ATerminated
NCT00997997BayerMoxifloxacin

Avelox in Complicated Skin and Skin Structure Infections

Start: Oct 2005Est. completion: Dec 20086,127 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

7 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.