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Skin Diseases

9
Pipeline Programs
9
Companies
10
Clinical Trials
2 recruiting
3
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
0
0
2
5
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
2100%
+ 11 programs with unclassified modality

On Market (3)

Approved therapies currently available

Pfizer
TYGACILApproved
tigecycline
Pfizer
Tetracycline-class Antibacterial [EPC]intravenous2005
85K Part D
GSK
FLONASEApproved
fluticasone propionate
GSK
nasal1994
GSK
FLONASE ALLERGY RELIEFApproved
fluticasone propionate
GSK
nasal2014

Competitive Landscape

9 companies ranked by most advanced pipeline stage

ViiV Healthcare
ViiV HealthcareNC - Durham
4 programs
1
2
3% Benzoyl PeroxidePhase 4
Fluticasone propionatePhase 4
MinocyclinePhase 1Small Molecule
Substance PN/A
GSK
GSKLONDON, United Kingdom
2 programs
1
Substance PN/A1 trial
Fluticasone propionatePHASE_41 trial
Active Trials
NCT04676763Completed32Est. Jul 2021
NCT01915914Completed107Est. Feb 2015
Pfizer
PfizerNEW YORK, NY
1 program
1
1
TigecyclinePhase 3Small Molecule1 trial
Active Trials
NCT00911573Withdrawn0Est. May 2014
AstraZeneca
AstraZenecaCAMBRIDGE, United Kingdom
1 program
1
DaptomycinPhase 31 trial
Active Trials
NCT00772447Completed265Est. Sep 2010
Prevail Therapeutics
1 program
1
LY3041658Phase 12 trials
Active Trials
NCT07545590Completed60Est. Sep 2026
NCT02896868Completed60Est. Mar 2019
Apollo Therapeutics
Apollo TherapeuticsUK - Cambridge
1 program
ApolloVue™ S100 image system, Viper1-S003N/A1 trial
Active Trials
NCT04066582Completed123Est. Oct 2019
Human BioSciences
Human BioSciencesWV - Martinsburg
1 program
Deep Phenotyping of CIndUN/A1 trial
Active Trials
NCT07359430Recruiting40Est. Jun 2026
Martin Pharmaceuticals
1 program
Micro-plasmapheresisN/A1 trial
Active Trials
NCT00186563Completed13
BeOne Medicines
BeOne MedicinesCA - San Carlos
1 program
BG-A3004PHASE_11 trial
Active Trials
NCT07412691Recruiting98Est. Aug 2028

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
GSKFluticasone propionate
PfizerTigecycline
AstraZenecaDaptomycin
Prevail TherapeuticsLY3041658
BeOne MedicinesBG-A3004
Prevail TherapeuticsLY3041658
Human BioSciencesDeep Phenotyping of CIndU
GSKSubstance P
Apollo TherapeuticsApolloVue™ S100 image system, Viper1-S003

Clinical Trials (10)

Total enrollment: 798 patients across 10 trials

NCT01915914GSKFluticasone propionate

A Randomized, Open-label, Comparative Study to Evaluate an Intermittent Dosing Regimen of Fluticasone Propionate 0.05% Cream (Twice Per Week) in Reducing the Risk of Relapse When Added to Regular Daily Moisturization Using PHYSIOGEL Lotion in Paediatric Subjects With Stabilized Atopic Dermatitis

Start: Dec 2013Est. completion: Feb 2015107 patients
Phase 4Completed

Study Evaluating Tigecycline Versus Clindamycin Or Vancomycin On Complicated Skin And Skin Structure Infections Including Those Due To Methicillin-Resistant Staphylococcus Aureus (MRSA) In Pediatric Subjects

Start: Aug 2011Est. completion: May 20140
Phase 3Withdrawn

China Registration Study in Patients With Skin Infections

Start: Sep 2008Est. completion: Sep 2010265 patients
Phase 3Completed

A Study of Eltrekibart (LY3041658) in Healthy Participants

Start: Apr 2026Est. completion: Sep 202660 patients
Phase 1Completed

A Study to Evaluate the Safety of BG-A3004 in Healthy Participants and Patients With Immune-Mediated Skin Diseases

Start: Mar 2026Est. completion: Aug 202898 patients
Phase 1Recruiting

A Study of LY3041658 in Participants With Skin Diseases

Start: Nov 2016Est. completion: Mar 201960 patients
Phase 1Completed

A Human In-vivo Model for the Detection of Inflammatory and Nociceptive Biomarkers

13 patients
N/ACompleted
NCT07359430Human BioSciencesDeep Phenotyping of CIndU

Deep Phenotyping of CIndU

Start: Jan 2025Est. completion: Jun 202640 patients
N/ARecruiting
NCT04676763GSKSubstance P

Substance P Challenge in Healthy Participants

Start: Mar 2021Est. completion: Jul 202132 patients
N/ACompleted
NCT04066582Apollo TherapeuticsApolloVue™ S100 image system, Viper1-S003

Early Feasibility Study: Application of OCT Imaging in Dermatology

Start: Jan 2018Est. completion: Oct 2019123 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 late-stage (Phase 3) programs, potential near-term approvals
2 actively recruiting trials targeting 798 patients
9 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.