Shingles

3
Pipeline Programs
2
Companies
3
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
1
0
0
0
1
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Vaccine
1100%
+ 2 programs with unclassified modality

Competitive Landscape

2 companies ranked by most advanced pipeline stage

M&
Merck & Co.RAHWAY, NJ
1 program
1
Zoster Vaccine LivePhase 4Vaccine1 trial
Active Trials
NCT02624375Completed10Est. Nov 2019
Dynavax Technologies
Dynavax TechnologiesCA - Emeryville
2 programs
1
1
Z-1018Phase 1/21 trial
Z-1018Phase 11 trial
Active Trials
NCT05245838Completed150Est. Oct 2022
NCT06569823Recruiting764Est. Nov 2031

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Merck & Co.Zoster Vaccine Live
Dynavax TechnologiesZ-1018
Dynavax TechnologiesZ-1018

Clinical Trials (3)

Total enrollment: 924 patients across 3 trials

NCT02624375Merck & Co.Zoster Vaccine Live

Immune Response to Shingles Vaccination

Start: Feb 2016Est. completion: Nov 201910 patients
Phase 4Completed

Safety and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adults 50 Years of Age and Over

Start: Jun 2024Est. completion: Nov 2031764 patients
Phase 1/2Recruiting

Trial to Evaluate the Safety, Tolerability, and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adult Volunteers

Start: Jan 2022Est. completion: Oct 2022150 patients
Phase 1Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 924 patients
2 companies competing in this space