Severe Combined Immunodeficiency Due to ADA Deficiency

2
Pipeline Programs
1
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
2
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

1 companies ranked by most advanced pipeline stage

Orchard Therapeutics
2 programs
2
Infusion of autologous cryopreserved EFS-ADA LV CD34+ cellsPhase 1/21 trial
Infusion of autologous cryopreserved EFS-ADA LV CD34+ cellsPhase 1/21 trial
Active Trials
NCT03765632CompletedEst. Sep 2022
NCT02999984CompletedEst. Sep 2019

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Orchard TherapeuticsInfusion of autologous cryopreserved EFS-ADA LV CD34+ cells
Orchard TherapeuticsInfusion of autologous cryopreserved EFS-ADA LV CD34+ cells

Clinical Trials (2)

NCT03765632Orchard TherapeuticsInfusion of autologous cryopreserved EFS-ADA LV CD34+ cells

Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID

Start: Jan 2018Est. completion: Sep 2022
Phase 1/2Completed
NCT02999984Orchard TherapeuticsInfusion of autologous cryopreserved EFS-ADA LV CD34+ cells

Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID

Start: Dec 2016Est. completion: Sep 2019
Phase 1/2Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 companies competing in this space