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Sensorineural Hearing Loss

1
Pipeline Programs
8
Companies
15
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

7 companies ranked by most advanced pipeline stage

Combined Therapeutics
1 program
1
Combination SolutionPhase 11 trial
Active Trials
NCT06025097Completed70Est. Oct 2023
Cochlear
CochlearAustralia - Macquarie Park
9 programs
CI624 Slim 20 ElectrodeN/A1 trial
CI632 Slim Modiolar ElectrodeN/A1 trial
CI632DN/A1 trial
CI632DN/A1 trial
Experimental sound coding strategyN/A1 trial
+4 more programs
Active Trials
NCT04741048Withdrawn0Est. Apr 2023
NCT04741009Completed10Est. Jun 2025
NCT04750642Completed42Est. Feb 2024
+6 more trials
Purdue Pharma
Purdue PharmaCT - Stamford
1 program
Hearing Aid ProgramN/A1 trial
Active Trials
NCT05568329Unknown60Est. May 2023
Envoy Medical
Envoy MedicalMN - White Bear Lake
1 program
Implantation of EsteemN/A1 trial
Active Trials
NCT02689349Completed117Est. Sep 2021
Oticon
OticonDenmark - Smørum
1 program
PupillometryN/A1 trial
Active Trials
NCT03212924Completed16Est. Mar 2018
Rinri Therapeutics
Rinri TherapeuticsUK - Sheffield
1 program
Otic neural progenitorsPHASE_1_21 trial
Active Trials
NCT07032038Not Yet Recruiting20Est. Feb 2028
Contineum Therapeutics
1 program
PIPE-505PHASE_1_21 trial
Active Trials
NCT04462198Completed28Est. Jun 2021

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
Rinri TherapeuticsOtic neural progenitors
Contineum TherapeuticsPIPE-505
Combined TherapeuticsCombination Solution
CochlearCI632D
Purdue PharmaHearing Aid Program
CochlearCI632 Slim Modiolar Electrode
CochlearCI632D
CochlearCI624 Slim 20 Electrode
OticonPupillometry
CochlearNucleus 7 Cochlear Implant System
CochlearHybrid SRW cochlear implant
CochlearExperimental sound coding strategy
Envoy MedicalImplantation of Esteem
CochlearNucleus Hybrid L24
CochlearNucleus Freedom Cochlear Implant System Pediatric Post-approval Study

Clinical Trials (15)

Total enrollment: 564 patients across 15 trials

NCT07032038Rinri TherapeuticsOtic neural progenitors

First In Human Randomised Trial of Rincell-1 in Adults With a Cochlear Implant

Start: May 2026Est. completion: Feb 202820 patients
Phase 1/2Not Yet Recruiting

Phase I/IIa Study Evaluating Safety and Efficacy of an Intratympanic Dose of PIPE-505 in Subjects With Hearing Loss

Start: Oct 2020Est. completion: Jun 202128 patients
Phase 1/2Completed

Intra-Tympanic Steroid With PRP Combination in Sensorineural Hearing Loss and Tinnitus.

Start: Sep 2023Est. completion: Oct 202370 patients
Phase 1Completed

Long-term Follow-up of a Cochlear Implant With Dexamethasone Eluting Electrode Array

Start: May 2025Est. completion: Mar 202819 patients
N/ARecruiting
NCT05568329Purdue PharmaHearing Aid Program

Appreciation for Music Processed by Hearing Aids

Start: Sep 2022Est. completion: May 202360 patients
N/AUnknown
NCT04741009CochlearCI632 Slim Modiolar Electrode

Perimodiolar Implant Performance in Adults With Low-Frequency Residual Hearing

Start: Dec 2021Est. completion: Jun 202510 patients
N/ACompleted

Cochlear Implant With Dexamethasone Eluting Electrode Array

Start: Oct 2021Est. completion: Feb 202442 patients
N/ACompleted
NCT04741048CochlearCI624 Slim 20 Electrode

Hearing Implant Performance in Adults With Low-Frequency Residual Hearing

Start: Mar 2021Est. completion: Apr 20230
N/AWithdrawn
NCT03212924OticonPupillometry

Listening Effort in Cochlear Implant Users

Start: Sep 2017Est. completion: Mar 201816 patients
N/ACompleted
NCT03467399CochlearNucleus 7 Cochlear Implant System

Clinical Evaluation of a Cochlear Implant System

Start: Jul 2016Est. completion: Sep 201746 patients
N/ACompleted
NCT02638883CochlearHybrid SRW cochlear implant

Implantation of the Cochlear™ Nucleus® Hybrid S Round Window (S-RW) in Adults

Start: Feb 2016Est. completion: Jun 20196 patients
N/ACompleted
NCT02698787CochlearExperimental sound coding strategy

Fundamental Asynchronous Stimulus Timing Sound Coding Study

Start: Dec 2015Est. completion: Nov 201811 patients
N/ACompleted
NCT02689349Envoy MedicalImplantation of Esteem

Esteem New Subject Enrollment Post Approval Study

Start: Aug 2010Est. completion: Sep 2021117 patients
N/ACompleted
NCT00678899CochlearNucleus Hybrid L24

Evaluation of the Nucleus Hybrid™ L24 Cochlear Implant System

Start: Apr 2008Est. completion: Jul 201450 patients
N/ACompleted
NCT00589511CochlearNucleus Freedom Cochlear Implant System Pediatric Post-approval Study

Nucleus Freedom Cochlear Implant System Pediatric Post-approval Study

Start: Oct 2006Est. completion: Jun 200969 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 564 patients
8 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.