Seasonal Allergic Conjunctivitis

4
Pipeline Programs
3
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
2
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Novartis
NovartisBASEL, Switzerland
1 program
1
KetotifenPhase 41 trial
Active Trials
NCT00133627Completed229Est. Oct 2005
Bausch + Lomb
Bausch + LombNJ - Bridgewater
2 programs
2
Brimonidine Tartrate 0.025%/ Ketotifen Fumarate 0.035% Ophthalmic SolutionPhase 31 trial
Loteprednol etabonate 0.2%Phase 31 trial
Active Trials
NCT05591755Completed229Est. Aug 2023
NCT01435460Completed300Est. May 2011
Thea Pharma
Thea PharmaMA - Waltham
1 program
1
T1210Phase 21 trial
Active Trials
NCT01344083CompletedEst. Feb 2012

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
NovartisKetotifen
Bausch + LombBrimonidine Tartrate 0.025%/ Ketotifen Fumarate 0.035% Ophthalmic Solution
Bausch + LombLoteprednol etabonate 0.2%
Thea PharmaT1210

Clinical Trials (4)

Total enrollment: 758 patients across 4 trials

Ketotifen Ophthalmic Solution With Emedastine in Patients With Seasonal Allergic Conjunctivitis

Start: Apr 2005Est. completion: Oct 2005229 patients
Phase 4Completed
NCT05591755Bausch + LombBrimonidine Tartrate 0.025%/ Ketotifen Fumarate 0.035% Ophthalmic Solution

Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination in Adults With Seasonal Allergic Conjunctivitis

Start: Nov 2022Est. completion: Aug 2023229 patients
Phase 3Completed
NCT01435460Bausch + LombLoteprednol etabonate 0.2%

Alrex® Versus Patanol in the Treatment of Seasonal Allergic Conjunctivitis(SAC)

Start: Aug 2010Est. completion: May 2011300 patients
Phase 3Completed

Comparison of the Efficacy and Tolerability of T1210 and Olopatadine Hydrochloride 0.1% in the Treatment of Seasonal Allergic Conjunctivitis

Start: Apr 2011Est. completion: Feb 2012
Phase 2Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 late-stage (Phase 3) programs — potential near-term approvals
3 companies competing in this space