Scleroderma, Diffuse

3
Pipeline Programs
3
Companies
3
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Cell Therapy
1100%
+ 2 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Inventiva
InventivaDAIX, France
1 program
1
IVA337Phase 21 trial
Active Trials
NCT02503644CompletedEst. Oct 2018
Novartis
NovartisBASEL, Switzerland
1 program
1
rapcabtagene autoleucelPhase 2Cell Therapy1 trial
Active Trials
NCT06655896Recruiting96Est. Aug 2032
Bristol Myers Squibb
1 program
1
AVID200Phase 11 trial
Active Trials
NCT03831438Completed9Est. Jun 2020

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Novartisrapcabtagene autoleucel
InventivaIVA337
Bristol Myers SquibbAVID200

Clinical Trials (3)

Total enrollment: 105 patients across 3 trials

NCT06655896Novartisrapcabtagene autoleucel

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

Start: Oct 2024Est. completion: Aug 203296 patients
Phase 2Recruiting

Proof-of-concept Trial of IVA337 in Diffuse Cutaneous Systemic Sclerosis

Start: Oct 2015Est. completion: Oct 2018
Phase 2Completed

Safety and Tolerability Study of AVID200 in Pts With Diffuse Cutaneous Systemic Sclerosis

Start: Jan 2019Est. completion: Jun 20209 patients
Phase 1Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 105 patients
3 companies competing in this space