SARS-CoV-2 Infection

14
Pipeline Programs
15
Companies
17
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
4
3
2
2
3
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

RNA Therapeutic
360%
Vaccine
120%
Small Molecule
120%
+ 13 programs with unclassified modality

Competitive Landscape

14 companies ranked by most advanced pipeline stage

Allergy Therapeutics
Allergy TherapeuticsUK - West Sussex
1 program
1
S-217622Phase 31 trial
Active Trials
NCT05305547CompletedEst. May 2024
Bayer
BayerLEVERKUSEN, Germany
1 program
1
SARS-CoV-2 mRNA VaccinePhase 3RNA Therapeutic1 trial
Active Trials
NCT04848467Withdrawn0Est. Nov 2022
C
CureVacGermany - Tübingen
1 program
1
SARS-CoV-2 mRNA VaccinePhase 3RNA Therapeutic
Celltrion
CelltrionKorea - Incheon
4 programs
3
1
CT-P59Phase 2/31 trial
CT-P59Phase 11 trial
CT-P59Phase 11 trial
CT-P63Phase 11 trial
Active Trials
NCT04593641Completed18Est. Apr 2021
NCT04525079Completed32Est. Nov 2020
NCT05017168Completed24Est. Jan 2022
+1 more trials
FP
Fosun PharmaAustralia - Sydney
1 program
1
AzvudinePhase 2/31 trial
Active Trials
NCT05633433UnknownEst. Jul 2024
Virogin Biotech
Virogin BiotechBC - Richmond
1 program
1
COVID-19 mRNA VaccinePhase 2RNA Therapeutic1 trial
Active Trials
NCT06113731UnknownEst. Oct 2024
Grifols
GrifolsNEW YORK, NY
1 program
1
Convalescent anti-SARS-CoV-2 MBT plasmaPhase 21 trial
Active Trials
NCT04621123CompletedEst. Jul 2021
Boehringer Ingelheim
Boehringer IngelheimINGELHEIM, Germany
2 programs
2
DZIF-10cPhase 1/21 trial
DZIF-10cPhase 1/21 trial
Active Trials
NCT04631705Terminated45Est. Sep 2021
NCT04631666Completed57Est. Aug 2021
Bharat Serums & Vaccines
1 program
1
Equine COVID-19 AntiserumPhase 1/21 trial
Active Trials
NCT04834908TerminatedEst. May 2022
Memo Therapeutics
Memo TherapeuticsSwitzerland - Schlieren
1 program
1
MTx-COVAB36Phase 11 trial
Active Trials
NCT05351437Completed32Est. Nov 2022
AstraZeneca
AstraZenecaCAMBRIDGE, United Kingdom
1 program
Evusheld Japan PMS_Japan Post-Marketing Surveillance (PMS)N/A1 trial
Active Trials
NCT05687877Completed366Est. Jan 2025
Alder Therapeutics
Alder TherapeuticsSweden - Solna
1 program
Innova Lateral Flow TestN/A1 trial
Active Trials
NCT05614427Completed449Est. Apr 2022
Heidelberg Pharma
Heidelberg PharmaGermany - Ladenburg
1 program
Sinopharm VaccineN/AVaccine1 trial
Active Trials
NCT05362682Unknown3,000Est. Aug 2024
Pfizer
PfizerNEW YORK, NY
1 program
nirmatrelvir / ritonavirN/ASmall Molecule1 trial
Active Trials
NCT05263908Completed3,346Est. Jul 2023

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Allergy TherapeuticsS-217622
BayerSARS-CoV-2 mRNA Vaccine
Fosun PharmaAzvudine
CelltrionCT-P59
Virogin BiotechCOVID-19 mRNA Vaccine
GrifolsConvalescent anti-SARS-CoV-2 MBT plasma
Bharat Serums & VaccinesEquine COVID-19 Antiserum
Boehringer IngelheimDZIF-10c
Boehringer IngelheimDZIF-10c
Memo TherapeuticsMTx-COVAB36
CelltrionCT-P63
CelltrionCT-P59
CelltrionCT-P59
AstraZenecaEvusheld Japan PMS_Japan Post-Marketing Surveillance (PMS)
Pfizernirmatrelvir / ritonavir

Showing 15 of 17 trials with date data

Clinical Trials (17)

Total enrollment: 9,011 patients across 17 trials

A Study to Compare S-217622 With Placebo in Non-Hospitalized Participants With COVID-19

Start: Aug 2022Est. completion: May 2024
Phase 3Completed
NCT04848467BayerSARS-CoV-2 mRNA Vaccine

COVID-19: A Trial Studying the SARS-CoV-2 mRNA Vaccine CVnCoV to Learn About the Immune Response, the Safety, and the Degree of Typical Vaccination Reactions When CVnCoV is Given at the Same Time as a Flu Vaccine Compared to When the Vaccines Are Separately Given in Adults 60 Years of Age and Older

Start: Oct 2021Est. completion: Nov 20220
Phase 3Withdrawn

Evaluate the Efficacy and Safety of Azvudine in Preventing SARS-Cov-2 Infection in Household Contacts of Covid-19

Start: Dec 2022Est. completion: Jul 2024
Phase 2/3Unknown

A Phase 2/3 Study to Evaluate the Efficacy and Safety of CT-P59 in Patients With Mild to Moderate SARS-CoV-2 Infection

Start: Oct 2020Est. completion: Oct 20211,642 patients
Phase 2/3Completed
NCT06113731Virogin BiotechCOVID-19 mRNA Vaccine

A PhaseⅡ Study to Evaluate the Safety and Immunogenicity of COVID-19 Vaccine

Start: Jul 2023Est. completion: Oct 2024
Phase 2Unknown
NCT04621123GrifolsConvalescent anti-SARS-CoV-2 MBT plasma

Plasma for Early Treatment in Non-hospitalised Mild or Moderate COVID-19 Patients

Start: Nov 2020Est. completion: Jul 2021
Phase 2Completed
NCT04834908Bharat Serums & VaccinesEquine COVID-19 Antiserum

Evaluation of Equine Antibody Treatment in Patients With COVID 19 Infection

Start: Jul 2021Est. completion: May 2022
Phase 1/2Terminated

SARS-CoV-2-Neutralizing Monoclonal COVID-19 Antibody DZIF-10c by Inhalation

Start: Dec 2020Est. completion: Sep 202145 patients
Phase 1/2Terminated

SARS-CoV-2-Neutralizing Monoclonal COVID-19 Antibody DZIF-10c by Infusion

Start: Dec 2020Est. completion: Aug 202157 patients
Phase 1/2Completed

To Assess the Safety and Tolerability of MTx-COVAB36 as a Therapeutic and Prophylactic Treatment Against COVID-19.

Start: Apr 2022Est. completion: Nov 202232 patients
Phase 1Completed

To Evaluate the Safety, Tolerability and Pharmacokinetics of CT-P63 in Healthy Subjects

Start: Oct 2021Est. completion: Jan 202224 patients
Phase 1Completed

This is a Phase 1 Study to Evaluate the Safety,Tolerability and Virology of CT P59 in Patients With Mild Symptoms of Symptoms of Coronavirus Disease (COVID-19)

Start: Sep 2020Est. completion: Apr 202118 patients
Phase 1Completed

To Evaluate the Safety, Tolerability and Pharmacokinetics of CT-P59 in Healthy Subjects

Start: Jul 2020Est. completion: Nov 202032 patients
Phase 1Completed
NCT05687877AstraZenecaEvusheld Japan PMS_Japan Post-Marketing Surveillance (PMS)

Evusheld Japan PMS_Japan Post-Marketing Surveillance (PMS)

Start: Jan 2023Est. completion: Jan 2025366 patients
N/ACompleted
NCT05263908Pfizernirmatrelvir / ritonavir

A Study to Learn About PAXLOVID (a Commercial Medicine) In People With COVID-19

Start: Mar 2022Est. completion: Jul 20233,346 patients
N/ACompleted

Effectiveness Evaluation of the Sinopharm Vaccine in the Dondo District in Mozambique

Start: Feb 2022Est. completion: Aug 20243,000 patients
N/AUnknown
NCT05614427Alder TherapeuticsInnova Lateral Flow Test

The LAVA (Lateral Flow Antigen Validation and Applicability) 2 Study for COVID-19

Start: Mar 2021Est. completion: Apr 2022449 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 late-stage (Phase 3) programs — potential near-term approvals
15 companies competing in this space