Sarcopenia

2
Pipeline Programs
9
Companies
8
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

7 companies ranked by most advanced pipeline stage

Biophytis
BiophytisFrance - Paris
2 programs
1
BIO101Phase 21 trial
No Drug and no aspecific interventionN/A1 trial
Active Trials
NCT03021798CompletedEst. Jun 2020
NCT03452488CompletedEst. Apr 2020
Regeneron
RegeneronTARRYTOWN, NY
1 program
1
REGN1033Phase 2
Abbott
AbbottABBOTT PARK, IL
2 programs
Low-magnitude High-frequency VibrationN/A1 trial
Muscle Mass and Function in Chinese AdultsN/A1 trial
Active Trials
NCT05525039Recruiting200Est. Sep 2025
NCT02089971Completed412Est. Dec 2014
M&
Merck & Co.RAHWAY, NJ
1 program
Blood Flow, Muscle Regeneration and SarcopeniaN/A1 trial
Active Trials
NCT01035060Completed68Est. Dec 2011
NMD Pharma
NMD PharmaDenmark - Aarhus
1 program
Investigating Loss of Neuromuscular Junction Transmission Fidelity in Older AdultsN/A1 trial
Active Trials
NCT04904926Completed19Est. Sep 2021
Abiogen
AbiogenItaly - Pisa
1 program
OLEPN/A1 trial
Active Trials
NCT04702087UnknownEst. Dec 2022
AB
AP BiosciencesTaiwan - Taipei
1 program
insect, pea or whey proteinN/A1 trial
Active Trials
NCT04633694CompletedEst. Nov 2023

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
BiophytisBIO101
AbbottLow-magnitude High-frequency Vibration
NMD PharmaInvestigating Loss of Neuromuscular Junction Transmission Fidelity in Older Adults
AbiogenOLEP
AP Biosciencesinsect, pea or whey protein
BiophytisNo Drug and no aspecific intervention
AbbottMuscle Mass and Function in Chinese Adults
Merck & Co.Blood Flow, Muscle Regeneration and Sarcopenia

Clinical Trials (8)

Total enrollment: 699 patients across 8 trials

NCT03452488BiophytisBIO101

A Double-blind, Placebo-controlled, Randomized INTerventional Clinical Trial (SARA-INT)

Start: Feb 2017Est. completion: Apr 2020
Phase 2Completed
NCT05525039AbbottLow-magnitude High-frequency Vibration

RCT of Combination Effect of Vibration Treatment and HMB Supplementation on Myosteatosis and NMJ Degeneration

Start: Jan 2023Est. completion: Sep 2025200 patients
N/ARecruiting
NCT04904926NMD PharmaInvestigating Loss of Neuromuscular Junction Transmission Fidelity in Older Adults

Investigating Loss of Neuromuscular Junction Transmission Fidelity in Older Adults

Start: Mar 2021Est. completion: Sep 202119 patients
N/ACompleted
NCT04702087AbiogenOLEP

Omega 3, Leucine, Probiotic Lactobacillus Paracasei PS23 on Muscle Mass in Sarcopenic Subjects

Start: Jan 2021Est. completion: Dec 2022
N/AUnknown
NCT04633694AP Biosciencesinsect, pea or whey protein

Insect Protein and Muscle Protein Signaling

Start: Jun 2020Est. completion: Nov 2023
N/ACompleted
NCT03021798BiophytisNo Drug and no aspecific intervention

An OBServational Clinical Trial (SARA-OBS) in Sarcopenia and Sarcopenic Obesity in Patients Aged 65 Years and Over

Start: Feb 2017Est. completion: Jun 2020
N/ACompleted
NCT02089971AbbottMuscle Mass and Function in Chinese Adults

Muscle Mass and Function in Chinese Adults

Start: Mar 2014Est. completion: Dec 2014412 patients
N/ACompleted
NCT01035060Merck & Co.Blood Flow, Muscle Regeneration and Sarcopenia

Blood Flow, Muscle Regeneration and Sarcopenia

Start: Jun 2010Est. completion: Dec 201168 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 699 patients
9 companies competing in this space