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Rotator Cuff Tears

2
Pipeline Programs
13
Companies
21
Clinical Trials
7 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
1
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

13 companies ranked by most advanced pipeline stage

ChitogenX
ChitogenXQC - Kirkland
1 program
1
Ortho-R/PRPPhase 1/21 trial
Active Trials
NCT05333211Unknown78Est. May 2024
Angiocrine Bioscience
Angiocrine BioscienceCA - San Diego
1 program
1
E-CEL UVECPhase 14 trials
Active Trials
NCT07557134Not Yet Recruiting78Est. Dec 2029
NCT06456073Recruiting20Est. Dec 2026
NCT04190862Recruiting39Est. Jun 2032
+1 more trials
Anika Therapeutics
Anika TherapeuticsMA - Bedford
2 programs
Anika Integrity Implant SystemN/A1 trial
Rotator Cuff ImplantN/A
Active Trials
NCT06353893Active Not Recruiting20Est. May 2026
CONMED
CONMEDCO - Greenwood Village
2 programs
Arthroscopic rotator cuff repair with BioBrace® Implant augmentation.N/A1 trial
Bridging Reconstruction using BioBraceN/A1 trial
Active Trials
NCT05997381Recruiting268Est. Jun 2027
NCT05959733Recruiting60Est. Jul 2027
Arthrex
ArthrexCA - Santa Barbara
2 programs
Autologous conditioned plasmaN/A1 trial
Patch Augmentation and ACP injectionN/A1 trial
Active Trials
NCT01266226Completed129Est. Feb 2015
NCT01586351Completed20Est. Mar 2016
Stryker
StrykerCA - San Jose
2 programs
InSpace Subacromial Tissue SpacerN/A1 trial
Shoulder iD™ Primary Reversed GlenoidN/A1 trial
Active Trials
NCT05329584Recruiting160Est. Dec 2026
NCT05868148Active Not Recruiting200Est. Dec 2035
Zimmer Biomet
Zimmer BiometFL - Jacksonville
2 programs
PMCF Study on the Safety, Performance and Clinical Benefits Data of the Quattro X BroadbandN/A1 trial
Tapestry Biointegrative ImplantN/A1 trial
Active Trials
NCT05690776Completed106Est. Nov 2024
NCT06287853Suspended170Est. Dec 2030
Atreon Orthopedics
2 programs
Rotium nanoscaffoldN/A1 trial
nanofiber scaffoldN/A1 trial
Active Trials
NCT04361266Withdrawn0Est. Nov 2023
NCT04325789Completed91Est. Dec 2025
Skye Biologics
Skye BiologicsCA - El Segundo
1 program
ActiveMatrix® Dosage AN/A1 trial
Active Trials
NCT05894265Recruiting60Est. Aug 2026
InGeneron
InGeneronGermany - Munich
1 program
Adipose-derived stem cellsN/A1 trial
Active Trials
NCT04077190Completed15Est. Dec 2021
Biocorp
BiocorpFrance - Issoire
1 program
AssessmentN/A1 trial
Active Trials
NCT05232773Unknown42Est. Jul 2023
MicroPort
MicroPortChina - Shanghai
1 program
Balloon implantationN/A1 trial
Active Trials
NCT04538001Unknown112Est. Sep 2022
Connect Biopharma
Connect BiopharmaSAN DIEGO, CA
1 program
Band ConnectN/A1 trial
Active Trials
NCT06733480Recruiting499Est. Jun 2026

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Angiocrine BioscienceE-CEL UVEC
ChitogenXOrtho-R/PRP
Angiocrine BioscienceE-CEL UVEC
Angiocrine BioscienceE-CEL UVEC
Angiocrine BioscienceE-CEL UVEC
Zimmer BiometTapestry Biointegrative Implant
Connect BiopharmaBand Connect
Anika TherapeuticsAnika Integrity Implant System
CONMEDArthroscopic rotator cuff repair with BioBrace® Implant augmentation.
CONMEDBridging Reconstruction using BioBrace
StrykerShoulder iD™ Primary Reversed Glenoid
Skye BiologicsActiveMatrix® Dosage A
Atreon OrthopedicsRotium nanoscaffold
Zimmer BiometPMCF Study on the Safety, Performance and Clinical Benefits Data of the Quattro X Broadband
StrykerInSpace Subacromial Tissue Spacer

Showing 15 of 21 trials with date data

Clinical Trials (21)

Total enrollment: 2,187 patients across 21 trials

E-CEL UVEC Cell Injection Treatment of Perianal Fistulas

Start: May 2027Est. completion: Dec 202978 patients
Phase 2Not Yet Recruiting

Ortho-R® for Rotator Cuff Repair Compared With Standard of Care Rotator Cuff Repair Without Ortho-R®

Start: Jul 2022Est. completion: May 202478 patients
Phase 1/2Unknown

E-CEL UVEC Treatment for Anal Fissures

Start: Sep 2024Est. completion: Dec 202620 patients
Phase 1Recruiting

E-CEL UVEC as an Adjunct Cell Therapy for Treatment of Anal Fistulas

Start: Jan 2020Est. completion: Jun 203239 patients
Phase 1Recruiting

E-CEL UVEC Cells as an Adjunct Cell Therapy for the Arthroscopic Rotator Cuff Repair in Adults

Start: Nov 2019Est. completion: Oct 202620 patients
Phase 1Enrolling By Invitation
NCT06287853Zimmer BiometTapestry Biointegrative Implant

Tapestry Rotator Cuff Repair PMCF

Start: Dec 2026Est. completion: Dec 2030170 patients
N/ASuspended

Innovating Physical Therapy: A Pilot Study on Band Connect's Impact on Compliance, Satisfaction, and Revenue

Start: Feb 2025Est. completion: Jun 2026499 patients
N/ARecruiting
NCT06353893Anika TherapeuticsAnika Integrity Implant System

MRI Evaluation of Integrity Implant for Rotator Cuff Tears

Start: Apr 2024Est. completion: May 202620 patients
N/AActive Not Recruiting
NCT05997381CONMEDArthroscopic rotator cuff repair with BioBrace® Implant augmentation.

BioBrace® Implant for Arthroscopic Repair of Full Thickness Rotator Cuff Tears

Start: Jan 2024Est. completion: Jun 2027268 patients
N/ARecruiting
NCT05959733CONMEDBridging Reconstruction using BioBrace

Maximal Repair Versus Bridging Reconstruction with BioBrace®

Start: Dec 2023Est. completion: Jul 202760 patients
N/ARecruiting
NCT05868148StrykerShoulder iD™ Primary Reversed Glenoid

Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study

Start: Oct 2023Est. completion: Dec 2035200 patients
N/AActive Not Recruiting
NCT05894265Skye BiologicsActiveMatrix® Dosage A

Prospective Study to Determine the Safety and Effectiveness of a Connective Tissue Allograft Active Matrix (AM) vs. Standard of Care in Arthroscopic Rotator Cuff Repair

Start: Jun 2023Est. completion: Aug 202660 patients
N/ARecruiting

Use of Nanoscaffold Augmentation in Rotator Cuff Repair: Clinical Outcome and Ultrasound Assessment of Healing Rates and Vascularity

Start: Aug 2022Est. completion: Nov 20230
N/AWithdrawn
NCT05690776Zimmer BiometPMCF Study on the Safety, Performance and Clinical Benefits Data of the Quattro X Broadband

PMCF Study on the Safety, Performance and Clinical Benefits Data of the Quattro X Broadband

Start: Jun 2022Est. completion: Nov 2024106 patients
N/ACompleted
NCT05329584StrykerInSpace Subacromial Tissue Spacer

InSpace Accelerated Rehabilitation Study

Start: Feb 2022Est. completion: Dec 2026160 patients
N/ARecruiting

Rotator Cuff Surgery in Athletes: From Rehabilitation to Return to Sport

Start: Jan 2022Est. completion: Jul 202342 patients
N/AUnknown
NCT04538001MicroPortBalloon implantation

Safety and Efficacy of Rotator Cuff Function Restoration Balloon in Irreparable Rotator Cuff Tear

Start: Sep 2020Est. completion: Sep 2022112 patients
N/AUnknown

Rotator Cuff Healing Using a Nanofiber Scaffold in Patients Greater Than 55 Years

Start: Jun 2020Est. completion: Dec 202591 patients
N/ACompleted
NCT04077190InGeneronAdipose-derived stem cells

Safety and Efficacy of Adult Adipose-Derived Stem Cell Injection Into Partial Thickness Rotator Cuff Tears

Start: Aug 2019Est. completion: Dec 202115 patients
N/ACompleted
NCT01586351ArthrexPatch Augmentation and ACP injection

Rotator Cuff Reconstruction With Xenologous Dermis-patch Augmentation and ACP® - Injection

Start: Oct 2012Est. completion: Mar 201620 patients
N/ACompleted
NCT01266226ArthrexAutologous conditioned plasma

Effect of ACP on Surgical Repair of Rotator Cuff Tears

Start: Dec 2010Est. completion: Feb 2015129 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

7 actively recruiting trials targeting 2,187 patients
13 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.