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Rib Fractures

5
Pipeline Programs
5
Companies
4
Clinical Trials
3
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
5
Early DiscoveryClinical DevelopmentMarket

On Market (3)

Approved therapies currently available

BUPIVACAINE LIPOSOMEApproved
bupivacaine
Unknown Company
Amide Local Anesthetic [EPC]injection2024
EXPARELApproved
bupivacaine
Unknown Company
Amide Local Anesthetic [EPC]injection2011
POSIMIRApproved
bupivacaine
Unknown Company
infiltration2021

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
1 program
1
BupivacainePhase 4
Angeles Therapeutics
Angeles TherapeuticsCA - Los Angeles
1 program
1
BupivacainePhase 41 trial
Active Trials
NCT03619785Unknown70Est. Aug 2019
Monaghan Medical
Monaghan MedicalNY - Plattsburgh
1 program
Oscillating Positive Expiratory Pressure DeviceN/A1 trial
Active Trials
NCT04100512Unknown50Est. Oct 2023
Zimmer Biomet
Zimmer BiometFL - Jacksonville
1 program
RibFix AdvantageN/A1 trial
Active Trials
NCT05179005Terminated1Est. Dec 2023
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
1 program
Thoracic epidural catheter placementN/A1 trial
Active Trials
NCT02295098Completed36Est. Jun 2017

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Angeles TherapeuticsBupivacaine
Zimmer BiometRibFix Advantage
Monaghan MedicalOscillating Positive Expiratory Pressure Device
Colorado TherapeuticsThoracic epidural catheter placement

Clinical Trials (4)

Total enrollment: 157 patients across 4 trials

NCT03619785Angeles TherapeuticsBupivacaine

US-guided SAPB for Rib Fractures in the ED

Start: Nov 2018Est. completion: Aug 201970 patients
Phase 4Unknown
NCT05179005Zimmer BiometRibFix Advantage

RibFix Advantage™ Post-Market Follow-Up

Start: Apr 2023Est. completion: Dec 20231 patients
N/ATerminated
NCT04100512Monaghan MedicalOscillating Positive Expiratory Pressure Device

Oscillating Positive Expiratory Pressure (OPEP) Therapy in Trauma Patients With Multiple Rib Fractures

Start: Oct 2019Est. completion: Oct 202350 patients
N/AUnknown
NCT02295098Colorado TherapeuticsThoracic epidural catheter placement

Comparison of Epidural and Paracostal Catheter Placement for Pain Control After Rib Fractures

Start: Aug 2015Est. completion: Jun 201736 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

5 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.