Retinitis Pigmentosa (RP)

2
Pipeline Programs
2
Companies
2
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

RNA Therapeutic
1100%
+ 1 programs with unclassified modality

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Thea Pharma
Thea PharmaMA - Waltham
1 program
1
Intravitreal Injection of UltevursenPhase 2RNA Therapeutic1 trial
Active Trials
NCT06627179RecruitingEst. Dec 2027
jCyte
jCyteCA - Newport Beach
1 program
1
human retinal progenitor cellsPhase 1/21 trial
Active Trials
NCT02320812Completed28Est. Jul 2017

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Thea PharmaIntravitreal Injection of Ultevursen
jCytehuman retinal progenitor cells

Clinical Trials (2)

Total enrollment: 28 patients across 2 trials

NCT06627179Thea PharmaIntravitreal Injection of Ultevursen

Study to Evaluate Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene

Start: Dec 2024Est. completion: Dec 2027
Phase 2Recruiting
NCT02320812jCytehuman retinal progenitor cells

Safety of a Single, Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Retinitis Pigmentosa

Start: Jun 2015Est. completion: Jul 201728 patients
Phase 1/2Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 28 patients
2 companies competing in this space