Refractive Errors

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Pipeline Programs
3
Companies
30
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
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Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Alcon
AlconFORT WORTH, TX
28 programs
Comfilcon A with Digital Zone Optics™ contact lensesN/A1 trial
Contact lens with investigational coating 1N/A1 trial
DT1 Toric contact lensesN/A1 trial
Delefilcon A contact lensesN/A1 trial
Delefilcon A contact lensesN/A1 trial
+23 more programs
Active Trials
NCT03459131Completed15Est. Mar 2018
NCT03034928Completed33Est. Mar 2017
NCT04254003CompletedEst. Mar 2020
+25 more trials
Novartis
NovartisBASEL, Switzerland
1 program
Lotrafilcon B contact lenses with added wetting agentN/A1 trial
Active Trials
NCT03026257Completed323Est. Aug 2017
J&
Johnson & JohnsonNEW BRUNSWICK, NJ
1 program
narafilcon A contact lensN/A1 trial
Active Trials
NCT01444313Completed40

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
AlconVerofilcon A spherical soft contact lenses
AlconUV fs-Laser
AlconDelefilcon A contact lenses
AlconLotrafilcon A contact lenses
AlconLotrafilcon A contact lenses
AlconLotrafilcon B multifocal soft contact lenses
AlconLotrafilcon B spherical soft contact lenses
AlconLID220365 contact lens
AlconSerafilcon A contact lenses
AlconVerofilcon A contact lenses
AlconLehfilcon A contact lenses
AlconVerofilcon A toric contact lenses
AlconDelefilcon A contact lenses
AlconVerofilcon A toric contact lenses
AlconLID021201 contact lenses

Showing 15 of 30 trials with date data

Clinical Trials (30)

Total enrollment: 3,194 patients across 30 trials

NCT06462456AlconVerofilcon A spherical soft contact lenses

Post-market Clinical Follow-up Study of Alcon PRECISION1™ Spherical and PRECISION1™ for Astigmatism Soft Contact Lenses

Start: Aug 2024Est. completion: Mar 2025140 patients
N/ATerminated
NCT06021353AlconUV fs-Laser

Contralateral Study of WaveLight® Femtosecond Laser Devices for Corneal Flap Creation

Start: Oct 2023Est. completion: Dec 202447 patients
N/ACompleted
NCT06044948AlconDelefilcon A contact lenses

Clinical Assessment of a Daily Disposable Soft Silicone Hydrogel Contact Lens

Start: Oct 2023Est. completion: Nov 2023
N/ACompleted
NCT05992675AlconLotrafilcon A contact lenses

Air Optix® Night and Day® Aqua Continuous Wear

Start: Oct 2023Est. completion: Aug 20241,256 patients
N/ACompleted
NCT05976750AlconLotrafilcon A contact lenses

Air Optix® Night and Day® Aqua Daily Wear

Start: Oct 2023Est. completion: Jul 2024102 patients
N/ACompleted
NCT05886894AlconLotrafilcon B multifocal soft contact lenses

Air Optix Plus HydraGlyde Multifocal Daily/Extended Wear Contact Lenses

Start: Aug 2023Est. completion: Jun 2025
N/ACompleted
NCT05827224AlconLotrafilcon B spherical soft contact lenses

Air Optix Daily Wear Contact Lenses

Start: Aug 2023Est. completion: Jul 2024
N/ACompleted
NCT05725317AlconLID220365 contact lens

Clinical Performance Assessment of Two Silicone Hydrogel Daily Disposable Contact Lenses

Start: Jun 2023Est. completion: Jun 2023114 patients
N/ACompleted
NCT05431478AlconSerafilcon A contact lenses

Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses

Start: Jul 2022Est. completion: Sep 2022
N/ACompleted
NCT05138783AlconVerofilcon A contact lenses

Clinical Performance of Two Daily Disposable Soft Contact Lenses

Start: Jan 2022Est. completion: Mar 2022129 patients
N/ACompleted
NCT05056987AlconLehfilcon A contact lenses

Clinical Assessment of Two Daily Wear Reusable Soft Silicone Hydrogel Contact Lenses

Start: Jan 2022Est. completion: Jun 202236 patients
N/ACompleted
NCT05039112AlconVerofilcon A toric contact lenses

Clinical Comparison of 2 Daily Disposable Toric Soft Contact Lenses

Start: Sep 2021Est. completion: Nov 202164 patients
N/ACompleted
NCT05010512AlconDelefilcon A contact lenses

Clinical Performance of Two Commercial, Daily Disposable Contact Lenses

Start: Aug 2021Est. completion: Oct 2021112 patients
N/ACompleted
NCT04908488AlconVerofilcon A toric contact lenses

Clinical Performance of Two Daily Disposable Toric Soft Contact Lenses

Start: Jul 2021Est. completion: Sep 2021115 patients
N/ACompleted
NCT04702984AlconLID021201 contact lenses

Clinical Characterization of an Investigational Frequent Replacement Daily Wear Silicone Hydrogel Sphere Contact Lens

Start: Jan 2021Est. completion: Feb 202139 patients
N/ACompleted
NCT04631796AlconLehfilcon A contact lenses

Clinical Characterization of an Investigational Soft Silicone Hydrogel Contact Lens

Start: Dec 2020Est. completion: Dec 202036 patients
N/ACompleted
NCT04532099AlconLehfilcon A contact lenses

Clinical Comparison of Two Daily Wear Frequent Replacement Silicone Hydrogel Soft Contact Lenses

Start: Sep 2020Est. completion: May 2021
N/ACompleted
NCT04528017AlconVerofilcon A contact lenses

Clinical Comparison of 2 Daily Disposable Contact Lenses - Pilot Study 2

Start: Sep 2020Est. completion: Oct 202056 patients
N/ACompleted
NCT04403542AlconLehfilcon A contact lens

Pilot Clinical Performance of a Silicone Hydrogel Lens for Up to Six Nights of Extended Wear

Start: Aug 2020Est. completion: Aug 202036 patients
N/ACompleted
NCT04254003AlconDT1 Toric contact lenses

Clinical Performance Evaluation of Two Daily Disposable Silicone Hydrogel Toric Contact Lenses

Start: Feb 2020Est. completion: Mar 2020
N/ACompleted
NCT04207749AlconLID015385 contact lenses

Clinical Evaluation of a Daily Wear Silicone Hydrogel Lens

Start: Jan 2020Est. completion: Dec 2020249 patients
N/ACompleted
NCT04055519AlconLehfilcon A contact lenses

Clinical Performance Assessment of a Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lens

Start: Sep 2019Est. completion: Dec 201936 patients
N/ACompleted
NCT03920280AlconLID015385 contact lenses

Clinical Evaluation of a Daily Wear Frequent Replacement Silicone Hydrogel Lens

Start: May 2019Est. completion: Oct 2019120 patients
N/ACompleted
NCT03762668AlconModified delefilcon A contact lenses

Performance Assessment of a Modified Daily Disposable Contact Lens

Start: Dec 2018Est. completion: Jan 201962 patients
N/ACompleted
NCT03614130AlconLID011121 contact lens

Clinical Performance of a Silicone Hydrogel Contact Lens Following Six Nights of Extended Wear

Start: Aug 2018Est. completion: Sep 201822 patients
N/ACompleted
NCT03560141AlconLID011121 contact lens

Clinical Performance of a Silicone Hydrogel Contact Lens Following One Night of Extended Wear

Start: Jul 2018Est. completion: Jul 201812 patients
N/ACompleted
NCT03459131AlconComfilcon A with Digital Zone Optics™ contact lenses

Clinical Evaluation of Two Monthly Contact Lenses

Start: Mar 2018Est. completion: Mar 201815 patients
N/ACompleted
NCT03034928AlconContact lens with investigational coating 1

Clinical Biocompatibility Evaluation of Contact Lens Coatings

Start: Feb 2017Est. completion: Mar 201733 patients
N/ACompleted
NCT03026257NovartisLotrafilcon B contact lenses with added wetting agent

Clinical Assessment of a HYDRAGLYDE® Regimen

Start: Feb 2017Est. completion: Aug 2017323 patients
N/ACompleted
NCT01444313Johnson & Johnsonnarafilcon A contact lens

Prospective Study of the Health Benefits of Ultra-Violet Filtering Contact Lenses

Start: Jan 201140 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 companies competing in this space