Refractive Error

0
Pipeline Programs
4
Companies
43
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
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Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Alcon
AlconFORT WORTH, TX
21 programs
Balafilcon A contact lensN/A1 trial
Clear Care Plus contact lens solutionN/A1 trial
Delefilcon A Multifocal Contact Lenses with Molded MarkN/A
Delefilcon A contact lensesN/A
Delefilcon A contact lensesN/A1 trial
+16 more programs
Active Trials
NCT01629706CompletedEst. Jan 2014
NCT02413333Completed133Est. Aug 2015
NCT02710292CompletedEst. Sep 2016
+16 more trials
J&
Johnson & JohnsonNEW BRUNSWICK, NJ
6 programs
ELITA SystemN/A1 trial
ExperimentalN/A5 trials
IntraLase iFS femtosecond laser and patient interfaceN/A1 trial
etafilcon AN/A1 trial
senofilcon A toric soft contact lensN/A1 trial
+1 more programs
Active Trials
NCT05713253Terminated96Est. Feb 2025
NCT06209476Completed30Est. Feb 2024
NCT05121909Completed274Est. Apr 2022
+9 more trials
Novartis
NovartisBASEL, Switzerland
3 programs
Delefilcon A Multifocal Contact Lenses with Molded MarkN/A1 trial
Delefilcon A contact lensesN/A1 trial
Delefilcon A multifocal contact lensesN/A1 trial
Active Trials
NCT02939170Completed87Est. Dec 2016
NCT02750813Completed252Est. Aug 2016
NCT02871375Completed170Est. Nov 2016
Abbott
AbbottABBOTT PARK, IL
1 program
STAR S4IR LASIK with iDesign AberrometerN/A1 trial
Active Trials
NCT01220466Completed77Est. Dec 2011

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Johnson & JohnsonExperimental
Johnson & JohnsonExperimental
Johnson & JohnsonExperimental
Johnson & JohnsonExperimental
Johnson & JohnsonExperimental
Johnson & JohnsonExperimental
Johnson & JohnsonELITA System
Johnson & JohnsonExperimental
AlconVerofilcon A contact lenses
Johnson & Johnsonspectacles
Johnson & JohnsonIntraLase iFS femtosecond laser and patient interface
Alconverofilcon A contact lenses
NovartisDelefilcon A Multifocal Contact Lenses with Molded Mark
NovartisDelefilcon A multifocal contact lenses
AlconLotrafilcon B contact lenses with EOBO-41

Showing 15 of 43 trials with date data

Clinical Trials (43)

Total enrollment: 6,255 patients across 43 trials

NCT05121909Johnson & JohnsonExperimental

A Study of Experimental Mouthwashes

Start: Nov 2021Est. completion: Apr 2022274 patients
Phase 4Completed
NCT02065414Johnson & JohnsonExperimental

A Clinical Trial to Test the Effect of Experimental Mouth Rinse on Gum Disease

Start: Mar 2014Est. completion: Jun 2014260 patients
Phase 4Completed
NCT02691507Johnson & JohnsonExperimental

Trial to Determine the Therapeutic Benefit of an OTC Cream on Dry, Itchy Skin of Adults and Children With Eczema

Start: Feb 2016Est. completion: Apr 201653 patients
Phase 2Completed
NCT01254773Johnson & JohnsonExperimental

Amyloid Imaging And Safety Study Of Subcutaneous Bapineuzumab In Subjects With Mild to Moderate Alzheimer's Disease

Start: Dec 2010Est. completion: Mar 2013146 patients
Phase 2Completed
NCT04921371Johnson & JohnsonExperimental

Six Week Study of Experimental Mouth Rinses: Effect on Gingivitis and Plaque

Start: Oct 2019Est. completion: Dec 2019157 patients
Phase 1Completed
NCT06209476Johnson & JohnsonExperimental

Clinical Investigation on Assessing the Repeatability and Reproducibility of Central and Peripheral Refractive Error

Start: Jan 2024Est. completion: Feb 202430 patients
N/ACompleted
NCT05713253Johnson & JohnsonELITA System

A PHASED, PROSPECTIVE, MULTI-CENTER STUDY OF THE ELITA SYSTEM

Start: Feb 2023Est. completion: Feb 202596 patients
N/ATerminated
NCT04381481Johnson & JohnsonExperimental

Studying the Impact of Product Packaging in a Virtual Store Environment

Start: May 2020Est. completion: Jul 20202,374 patients
N/ACompleted
NCT03888482AlconVerofilcon A contact lenses

Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 2

Start: Apr 2019Est. completion: Jun 2019
N/ACompleted
NCT03913377Johnson & Johnsonspectacles

Ocular Characteristics in Contact Lens and Spectacle Wear

Start: Apr 2019Est. completion: Jun 201978 patients
N/ACompleted
NCT03789669Johnson & JohnsonIntraLase iFS femtosecond laser and patient interface

A Prospective, Multi-Center Evaluation of Corneal Flap Creation Using Cheetah Femtosecond Laser System and Cheetah Patient Interface

Start: Dec 2018Est. completion: Mar 2023200 patients
N/ACompleted
NCT03349632Alconverofilcon A contact lenses

Clinical Comparison of 4 Daily Disposable Soft Contact Lenses

Start: Jan 2018Est. completion: Feb 201868 patients
N/ACompleted
NCT02939170NovartisDelefilcon A Multifocal Contact Lenses with Molded Mark

Initial Performance of a Daily Disposable Contact Lens Featuring Molded Marks

Start: Nov 2016Est. completion: Dec 201687 patients
N/ACompleted
NCT02871375NovartisDelefilcon A multifocal contact lenses

Clinical Assessment of DAILIES TOTAL1® (DT1) Multifocal

Start: Aug 2016Est. completion: Nov 2016170 patients
N/ACompleted
NCT02699684AlconLotrafilcon B contact lenses with EOBO-41

Comparison of Lotrafilcon B Lenses With Different Packaging Solutions

Start: May 2016Est. completion: Oct 2016
N/ACompleted
NCT02750813NovartisDelefilcon A contact lenses

ACUVUE® OASYS® 1-DAY vs DAILIES TOTAL1®

Start: Apr 2016Est. completion: Aug 2016252 patients
N/ACompleted
NCT02710292AlconDelefilcon A contact lenses

Clinical Evaluation of DAILIES TOTAL 1® Performance in a Japanese Population

Start: Apr 2016Est. completion: Sep 2016
N/ACompleted
NCT02696317AlconSenofilcon A contact lenses with HydraLuxe™

Clinical Evaluation of ACUVUE® OASYS® 1-Day and ACUVUE® OASYS®

Start: Mar 2016Est. completion: Jun 201684 patients
N/ACompleted
NCT02517567AlconDelefilcon A contact lenses

DAILIES TOTAL1® - Comparative Assessment of Tear Film Evaporation

Start: Sep 2015Est. completion: Apr 201637 patients
N/ACompleted
NCT02413333AlconClear Care Plus contact lens solution

Clear Care® Plus vs. PeroxiClear™

Start: Apr 2015Est. completion: Aug 2015133 patients
N/ACompleted
NCT02388763AlconStenfilcon A contact lenses

Clinical Evaluation of MyDay™ and 1-DAY ACUVUE® TruEye®

Start: Apr 2015Est. completion: Sep 2015
N/ACompleted
NCT02357940Johnson & JohnsonExperimental

Tolerance Evaluation of a Nighttime Moisturizing Balm on Babies and Adults With Eczema

Start: Jan 2015Est. completion: Jan 201641 patients
N/ACompleted
NCT02089191AlconNelfilcon A contact lenses

Tear Film Stability of DAILIES® AquaComfort Plus® Contact Lenses vs. MyDay® Daily Disposable Contact Lenses

Start: Mar 2014Est. completion: Apr 2014
N/ACompleted
NCT02072980AlconDelefilcon A contact lenses

DAILIES TOTAL1® Lubricity Post Wear

Start: Mar 2014Est. completion: Apr 201415 patients
N/ACompleted
NCT01996709AlconHydrogen peroxide-based contact lens solution

Effectiveness of a Marketed One-Step Peroxide Lens Care Solution in Symptomatic Contact Lens Wearers

Start: Dec 2013Est. completion: May 2014142 patients
N/ACompleted
NCT02103309AlconNelfilcon A contact lenses

Comparative Evaluation of Contact Lens Centering of DAILIES® AquaComfort Plus® Versus 1-DAY ACUVUE® MOIST® in Japan

Start: Oct 2013Est. completion: Nov 2013
N/ACompleted
NCT01917162AlconNelfilcon A contact lens

Multi-Center Clinical Evaluation of Two Daily Disposable Contact Lenses (Study 2)

Start: Sep 2013Est. completion: Nov 201386 patients
N/ACompleted
NCT01941498AlconWavelight® Refractive Suite

WaveLight® Refractive Myopic Study

Start: Sep 2013Est. completion: Aug 2014
N/ACompleted
NCT01858701AlconLotrafilcon B toric contact lens

Visual Performance Investigation of Two Toric Soft Contact Lenses

Start: May 2013Est. completion: Oct 201349 patients
N/ACompleted
NCT01809197AlconLotrafilcon B contact lenses

Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution

Start: Apr 2013Est. completion: Jul 2013387 patients
N/ACompleted
NCT02055404AlconDelefilcon A spherical contact lens with molded marks

On-Eye Evaluation of Contact Lens Rotation Marks

Start: Feb 2013Est. completion: Feb 20133 patients
N/ACompleted
NCT01727258Johnson & JohnsonExperimental

A Test on a New Experimental Mouth Rinse for Relieving Tooth Sensitivity

Start: Dec 2012Est. completion: Feb 2013153 patients
N/ACompleted
NCT01629706AlconBalafilcon A contact lens

Determination of Cell Population in Solution-Induced Corneal Staining (SICS) and Symptomatic Versus Asymptomatic Lens Wearers

Start: Sep 2012Est. completion: Jan 2014
N/ACompleted
NCT01488604Johnson & JohnsonExperimental

A Study of an Experimental Nasal Spray in Subjects With Early Signs of the Common Cold

Start: Jan 2012Est. completion: May 2012163 patients
N/ACompleted
NCT01462110Johnson & JohnsonExperimental

A Four-Week Study to Measure the Effectiveness of an Experimental Mouthwash Used After Teeth Cleaning

Start: Nov 2011Est. completion: Dec 201187 patients
N/ACompleted
NCT01482819Johnson & Johnsonspectacles

Evaluation of Daytime Corneal Swelling During Wear of Galyfilcon A Lenses

Start: Oct 2011Est. completion: Dec 201121 patients
N/ACompleted
NCT01345292Johnson & JohnsonExperimental

A Study of the Relief of Tooth Sensitivity of an Experimental Mouthrinse Device

Start: Apr 2011Est. completion: May 2011226 patients
N/ACompleted
NCT01220466AbbottSTAR S4IR LASIK with iDesign Aberrometer

Performance and Acceptability of iDesign

Start: Oct 2010Est. completion: Dec 201177 patients
N/ACompleted
NCT01233089AlconLotrafilcon B contact lens, investigational

Fitting Children With Contact Lenses

Start: Sep 2010Est. completion: Aug 2011
N/ACompleted
NCT01156376Johnson & JohnsonExperimental

Oral Irritation Study of Two Experimental Mouthrinses

Start: Jun 2010Est. completion: Jul 201080 patients
N/ACompleted
NCT00708032Johnson & Johnsonspectacles

Clinical Performance of a New Daily Disposable Contact Lens Worn in a Neophyte Population.

Start: Jun 2008Est. completion: Dec 200974 patients
N/ACompleted
NCT00639353Johnson & Johnsonsenofilcon A toric soft contact lens

Silicone Hydrogel Contact Lenses on Low Astigmatism in Japan

Start: Feb 2008102 patients
N/ATerminated
NCT01163760Johnson & Johnsonetafilcon A

Clinical Evaluation of Two Daily Disposable Contact Lenses

Start: Sep 2007Est. completion: Sep 200750 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 companies competing in this space