Skip to main content

Reflux Oesophagitis

4
Pipeline Programs
3
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
4
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

TRIO Pharmaceuticals
TRIO PharmaceuticalsCA - San Carlos
4 programs
4
YF476Phase 1
YF476Phase 1
YF476Phase 1
YF476Phase 1
Trio Medicines
Trio MedicinesUK - London
4 programs
YF476PHASE_1
YF476PHASE_1
YF476PHASE_1
YF476PHASE_1
Ferring Pharmaceuticals
Ferring PharmaceuticalsArgentina - Buenos Aires
4 programs
YF476PHASE_11 trial
YF476PHASE_11 trial
YF476PHASE_11 trial
YF476PHASE_11 trial
Active Trials
NCT01538784Completed15Est. Jun 1996
NCT01597674Completed49Est. Jun 1997
NCT01599858Completed49Est. Oct 1996
+1 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Ferring PharmaceuticalsYF476
Ferring PharmaceuticalsYF476
Ferring PharmaceuticalsYF476
Ferring PharmaceuticalsYF476

Clinical Trials (4)

Total enrollment: 135 patients across 4 trials

Effect of 5, 10 or 25 mg of YF476 Daily for 14 Days on Stomach Acidity in Healthy Volunteers

Start: Apr 1997Est. completion: Jun 199749 patients
Phase 1Completed

Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy Volunteers

Start: Aug 1996Est. completion: Oct 199649 patients
Phase 1Completed

Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed States

Start: Jul 1996Est. completion: Aug 199622 patients
Phase 1Completed

Safety, Tolerability and Pharmacokinetics of Single Rising Doses of YF476, a Gastrin Antagonist, in Healthy Men

Start: May 1996Est. completion: Jun 199615 patients
Phase 1Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.