Reflux Oesophagitis

8
Pipeline Programs
2
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
8
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Ferring Pharmaceuticals
Ferring PharmaceuticalsArgentina - Buenos Aires
4 programs
4
YF476Phase 11 trial
YF476Phase 11 trial
YF476Phase 11 trial
YF476Phase 11 trial
Active Trials
NCT01538784Completed15Est. Jun 1996
NCT01597674Completed49Est. Jun 1997
NCT01599858Completed49Est. Oct 1996
+1 more trials
TM
Trio MedicinesUK - London
4 programs
4
YF476Phase 1
YF476Phase 1
YF476Phase 1
YF476Phase 1

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Ferring PharmaceuticalsYF476
Ferring PharmaceuticalsYF476
Ferring PharmaceuticalsYF476
Ferring PharmaceuticalsYF476

Clinical Trials (4)

Total enrollment: 135 patients across 4 trials

Effect of 5, 10 or 25 mg of YF476 Daily for 14 Days on Stomach Acidity in Healthy Volunteers

Start: Apr 1997Est. completion: Jun 199749 patients
Phase 1Completed

Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy Volunteers

Start: Aug 1996Est. completion: Oct 199649 patients
Phase 1Completed

Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed States

Start: Jul 1996Est. completion: Aug 199622 patients
Phase 1Completed

Safety, Tolerability and Pharmacokinetics of Single Rising Doses of YF476, a Gastrin Antagonist, in Healthy Men

Start: May 1996Est. completion: Jun 199615 patients
Phase 1Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 companies competing in this space