Skip to main content

Radiculopathy

6
Pipeline Programs
7
Companies
7
Clinical Trials
2
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
4
2
Early DiscoveryClinical DevelopmentMarket

On Market (2)

Approved therapies currently available

Viatris
LYRICAApproved
pregabalin
Viatris
oral2010
72M Part D
Viatris
LYRICA CRApproved
pregabalin
Viatris
oral2017
402K Part D

Competitive Landscape

7 companies ranked by most advanced pipeline stage

Viatris
ViatrisCANONSBURG, PA
1 program
1
1
pregabalinPhase 31 trial
Active Trials
NCT00159705Completed276Est. Jun 2007
NuVasive
NuVasiveCA - San Diego
2 programs
2
Anterior Cervical Discectomy and FusionPhase 31 trial
PCM Cervical DiscPhase 31 trial
Active Trials
NCT00578812Completed494Est. Aug 2014
NCT01905930Completed494Est. Apr 2015
Utah Medical
Utah MedicalIreland - Dublin
1 program
1
Physical therapy rehabilitationPhase 31 trial
Active Trials
NCT00979108Completed86Est. Jan 2013
Spine BioPharma
Spine BioPharmaNY - New York
1 program
ACDFN/A1 trial
Active Trials
NCT02350621Unknown80Est. Feb 2018
Medtronic
MedtronicNJ - Phillipsburg
1 program
ATLANTIS™ Cervical Plate System and allograftN/A1 trial
Active Trials
NCT00437190Completed494Est. May 2016
Nordic Pharma
Nordic PharmaFrance - Paris
1 program
Rhine Cervical DiscN/A1 trial
Active Trials
NCT02403453Terminated68Est. Mar 2023
Stryker
StrykerCA - San Jose
1 program
Rhine Cervical DiscN/A

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
NuVasivePCM Cervical Disc
Utah MedicalPhysical therapy rehabilitation
Viatrispregabalin
NuVasiveAnterior Cervical Discectomy and Fusion
Nordic PharmaRhine Cervical Disc
Spine BioPharmaACDF
MedtronicATLANTIS™ Cervical Plate System and allograft

Clinical Trials (7)

Total enrollment: 1,992 patients across 7 trials

NCT01905930NuVasivePCM Cervical Disc

Post-Approval Clinical Trial of the PCM® Cervical Disc

Start: Apr 2013Est. completion: Apr 2015494 patients
Phase 3Completed
NCT00979108Utah MedicalPhysical therapy rehabilitation

The Value of Traction in the Treatment of Cervical Radiculopathy

Start: Jul 2009Est. completion: Jan 201386 patients
Phase 3Completed
NCT00159705Viatrispregabalin

Trial of Efficacy and Safety of Pregabalin in Subjects With Neuropathic Pain Associated With Lumbo-Sacral Radiculopathy

Start: Apr 2005Est. completion: Jun 2007276 patients
Phase 3Completed
NCT00578812NuVasiveAnterior Cervical Discectomy and Fusion

PCM Cervical Disc System

Start: Jan 2005Est. completion: Aug 2014494 patients
Phase 3Completed
NCT02403453Nordic PharmaRhine Cervical Disc

RHINE™ Cervical Disc Clinical Study: A Prospective Observational Study for Patients Requiring 1-2 Level C-spine Surgery

Start: Jan 2016Est. completion: Mar 202368 patients
N/ATerminated
NCT02350621Spine BioPharmaACDF

Cervical Foraminal Stenosis and Radiculopathy - ACDF Versus Minimal Invasive Posterior Cervical Foraminotomy.

Start: Feb 2015Est. completion: Feb 201880 patients
N/AUnknown
NCT00437190MedtronicATLANTIS™ Cervical Plate System and allograft

Pivotal IDE Study of the BRYAN(R) Cervical Disc Prosthesis in the Treatment of DDD Versus ACDF

Start: Jun 2003Est. completion: May 2016494 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 late-stage (Phase 3) programs, potential near-term approvals
7 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.