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PTCL

4
Pipeline Programs
5
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
3
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
375%
Small Molecule
125%
+ 1 programs with unclassified modality

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Yingli Pharma
Yingli PharmaChina - Shanghai
1 program
1
YY-20394 treatmentPhase 21 trial
Active Trials
NCT04705090Unknown90Est. Jun 2023
MSD
MSDIreland - Ballydine
1 program
1
PembrolizumabPhase 1Monoclonal Antibody
Otsuka
OtsukaJapan - Tokushima
1 program
1
PembrolizumabPhase 1Monoclonal Antibody1 trial
Active Trials
NCT03240211Active Not Recruiting37Est. May 2026
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
1
PembrolizumabPhase 1Monoclonal Antibody
Boehringer Ingelheim
Boehringer IngelheimINGELHEIM, Germany
1 program
VolasertibPHASE_1Small Molecule1 trial
Active Trials
NCT02757248Withdrawn0Est. Nov 2016

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Yingli PharmaYY-20394 treatment
OtsukaPembrolizumab
Boehringer IngelheimVolasertib

Clinical Trials (3)

Total enrollment: 127 patients across 3 trials

NCT04705090Yingli PharmaYY-20394 treatment

A Study of YY-20394 in Patients With Relapsed or Refractory Peripheral T/NK Cell Lymphoma

Start: Apr 2021Est. completion: Jun 202390 patients
Phase 2Unknown
NCT03240211OtsukaPembrolizumab

Study of Pembrolizumab Combined With Decitabine and Pralatrexate in PTCL and CTCL

Start: Feb 2022Est. completion: May 202637 patients
Phase 1Active Not Recruiting

Ph1 Volasertib Plus Romidepsin in R/R PTCL and CTCL

Start: Nov 2016Est. completion: Nov 20160
Phase 1Withdrawn

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

Monoclonal Antibody is the dominant modality (75% of programs)
5 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.