Psychosis

5
Pipeline Programs
6
Companies
6
Clinical Trials
2 recruiting
3
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
0
4
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 5 programs with unclassified modality

On Market (3)

Approved therapies currently available

U
ARIPIPRAZOLEApproved
aripiprazole
Unknown Company
oral2024
U
MEZOFYApproved
aripiprazole
Unknown Company
oral2025
U
OPIPZAApproved
aripiprazole
Unknown Company
Atypical Antipsychotic [EPC]oral2024

Competitive Landscape

6 companies ranked by most advanced pipeline stage

AB
AP BiosciencesTaiwan - Taipei
1 program
1
AripiprazolePhase 4Small Molecule1 trial
Active Trials
NCT01119014CompletedEst. Jul 2015
Sandoz
SandozAustria - Kundl
1 program
1
Haloperidol 10 mg TabletsPhase 11 trial
Active Trials
NCT00946491CompletedEst. May 1987
Alliance Pharmaceuticals
1 program
Care CoordinationN/A1 trial
Active Trials
NCT06071858Recruiting350Est. Oct 2028
Genomics
GenomicsUK - Oxford
1 program
Genetic: Genomic sequencing and molecular diagnostic results, if any.N/A1 trial
Active Trials
NCT05457140Recruiting15Est. Aug 2026
M&
Merck & Co.RAHWAY, NJ
1 program
SCH 900460N/A1 trial
Active Trials
NCT00780585Completed95Est. Jan 2009
Verona Pharma
Verona PharmaUK - London
1 program
Treatment As UsualN/A1 trial
Active Trials
NCT01436331Completed626Est. May 2012

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
AP BiosciencesAripiprazole
SandozHaloperidol 10 mg Tablets
Alliance PharmaceuticalsCare Coordination
GenomicsGenetic: Genomic sequencing and molecular diagnostic results, if any.
Verona PharmaTreatment As Usual
Merck & Co.SCH 900460

Clinical Trials (6)

Total enrollment: 1,086 patients across 6 trials

NCT01119014AP BiosciencesAripiprazole

Tolerance and Effect of Antipsychotics in Children and Adolescents With Psychosis

Start: May 2010Est. completion: Jul 2015
Phase 4Completed
NCT00946491SandozHaloperidol 10 mg Tablets

To Demonstrate the Relative Bioequivalency of Generic Haloperidol Tablets Versus Haldol in Normal Volunteers

Start: Apr 1987Est. completion: May 1987
Phase 1Completed
NCT06071858Alliance PharmaceuticalsCare Coordination

Enhanced Coordinated Specialty Care for Early Psychosis

Start: Feb 2024Est. completion: Oct 2028350 patients
N/ARecruiting
NCT05457140GenomicsGenetic: Genomic sequencing and molecular diagnostic results, if any.

Multiomic Diagnostics in Youth With Psychosis

Start: Oct 2022Est. completion: Aug 202615 patients
N/ARecruiting
NCT01436331Verona PharmaTreatment As Usual

A Large Pragmatic Cluster Randomized Controlled Trial of a Multi-element Psychosocial Intervention for Early Psychosis

Start: Apr 2010Est. completion: May 2012626 patients
N/ACompleted
NCT00780585Merck & Co.SCH 900460

A Follow up Safety Study of Patients Who Participated in Previous Studies of the Drug Org 24448 (Study P05719)(COMPLETED)

Start: Apr 2007Est. completion: Jan 200995 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 actively recruiting trials targeting 1,086 patients
6 companies competing in this space