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Proteus Syndrome

4
Pipeline Programs
5
Companies
4
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Human BioSciences
Human BioSciencesWV - Martinsburg
3 programs
1
1
MK-7075Phase 2
MK-7075Phase 1
Study of Proteus Syndrome and Related Congenital DisordersN/A
Genome & Company
Genome & CompanyKorea - Suwon
3 programs
1
1
MK-7075Phase 21 trial
MK-7075Phase 11 trial
Study of Proteus Syndrome and Related Congenital DisordersN/A1 trial
Active Trials
NCT00001403Recruiting1,500
NCT02594215Completed6Est. Jun 2022
NCT04316546Recruiting45Est. Jul 2028
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
ARQ 092N/A1 trial
Active Trials
NCT03317366No Longer Available
Merck & Co.
Merck & Co.RAHWAY, NJ
1 program
ARQ 092N/A
MSD
MSDIreland - Ballydine
1 program
ARQ 092N/A

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
Genome & CompanyMK-7075
Genome & CompanyMK-7075
Genome & CompanyStudy of Proteus Syndrome and Related Congenital Disorders

Clinical Trials (4)

Total enrollment: 1,551 patients across 4 trials

MK-7075 (Miransertib) in Proteus Syndrome

Start: May 2022Est. completion: Jul 202845 patients
Phase 2Recruiting

Dose Finding Trial of MK-7075 in Children and Adults With Proteus Syndrome

Start: Nov 2015Est. completion: Jun 20226 patients
Phase 1Completed

Expanded Access to Provide ARQ 092 for the Treatment of Overgrowth Diseases and/or Vascular Anomalies

N/ANo Longer Available
NCT00001403Genome & CompanyStudy of Proteus Syndrome and Related Congenital Disorders

Study of Proteus Syndrome and Related Congenital Disorders

Start: Apr 19941,500 patients
N/ARecruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 actively recruiting trials targeting 1,551 patients
5 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.