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Primary Sjögren Syndrome

4
Pipeline Programs
6
Companies
6
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
2
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Escugen
EscugenChina - Shanghai
1 program
1
ESG206Phase 21 trial
Active Trials
NCT07375524Not Yet Recruiting40Est. Jun 2028
Resolve Therapeutics
1 program
1
RSLV-132Phase 21 trial
Active Trials
NCT06440525Recruiting106Est. Mar 2027
TearSolutions
TearSolutionsVA - Charlottesville
1 program
1
0.005% LacripepPhase 1/21 trial
Active Trials
NCT03226444Completed204Est. Dec 2019
UNION therapeutics
UNION therapeuticsDenmark - Hellerup
1 program
1
68Ga-P16-093Phase 1/21 trial
Active Trials
NCT06049368Unknown40Est. Mar 2024
LFB
LFBFrance - Paris
1 program
Collection sheetN/A1 trial
Active Trials
NCT03509064Recruiting100Est. Jan 2027
Galapagos
Galapagos2800 MECHELEN, Belgium
1 program
GLPG3970PHASE_21 trial
Active Trials
NCT04700280Terminated31Est. Dec 2021

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
EscugenESG206
Resolve TherapeuticsRSLV-132
GalapagosGLPG3970
UNION therapeutics68Ga-P16-093
TearSolutions0.005% Lacripep
LFBCollection sheet

Clinical Trials (6)

Total enrollment: 521 patients across 6 trials

A Phase 2 Study on the Safety and Efficacy of the Anti-BAFF-R Monoclonal Antibody, ESG206, in Patients With Primary Sjogren Syndrome

Start: Mar 2026Est. completion: Jun 202840 patients
Phase 2Not Yet Recruiting

A Study of RSLV-132 in Females With Sjögren's Disease

Start: Dec 2024Est. completion: Mar 2027106 patients
Phase 2Recruiting

A Study Evaluating the Effects of GLPG3970 Given as an Oral Treatment for 12 Weeks in Adults With Active Primary Sjögren's Syndrome (pSS)

Start: Jan 2021Est. completion: Dec 202131 patients
Phase 2Terminated

68Ga-P16-093 PET/CT Imaging in the Salivary Gland

Start: Oct 2023Est. completion: Mar 202440 patients
Phase 1/2Unknown

Lacripep™ in Subjects With Dry Eye Associated With Primary Sjögren's Syndrome

Start: Jun 2017Est. completion: Dec 2019204 patients
Phase 1/2Completed
NCT03509064LFBCollection sheet

Medico-economic and Quality of Life Impact of Sjogren-associated Small Fiber Neuropathy

Start: Jan 2019Est. completion: Jan 2027100 patients
N/ARecruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 actively recruiting trials targeting 521 patients
6 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.