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Primary Immunodeficiency Diseases (PID)

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Pipeline Programs
1
Companies
19
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
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Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

1 companies ranked by most advanced pipeline stage

Takeda
TakedaTOKYO, Japan
8 programs
CUVITRUN/A4 trials
Immune Globulin SubcutaneousN/A1 trial
Recombinant human hyaluronidase + immune globulin intravenousPHASE_1_21 trial
Immune Globulin IntravenousPHASE_25 trials
Immune Globulin IntravenousPHASE_2_31 trial
+3 more programs
Active Trials
NCT05764993Unknown40Est. Dec 2025
NCT04636502Completed96Est. Sep 2021
NCT03716700Completed126Est. Jul 2020
+12 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
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2024
2025
2026
2027
2028
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2030
TakedaCUVITRU
TakedaTAK-771
TakedaTAK-771
TakedaImmune Globulin Intravenous
TakedaImmune Globulin Intravenous
TakedaImmune Globulin Intravenous
TakedaSC treatment with IGSC, 10% with rHuPH20 followed by SC/IGSC, 10% only
TakedaImmune Globulin Intravenous
TakedaImmune Globulin Intravenous
TakedaImmune Globulin Intravenous
TakedaImmune Globulin Intravenous
TakedaImmune Globulin Intravenous
TakedaCUVITRU
TakedaImmune Globulin Intravenous
TakedaImmune Globulin Intravenous

Showing 15 of 19 trials with date data

Clinical Trials (19)

Total enrollment: 1,435 patients across 19 trials

Post-Authorization Safety, Tolerability and Immunogenicity Evaluation of HyQvia in Pediatric PIDD Subjects

Start: May 2017Est. completion: Jan 202142 patients
Phase 4Completed

A Study to Evaluate the Long-term Safety of TAK-771 in Japanese Primary Immunodeficiency Disease (PID) Participants

Start: Sep 2022Est. completion: Oct 202515 patients
Phase 3Completed

A Study of TAK-771 in Japanese People With Primary Immunodeficiency Diseases (PID)

Start: Jan 2022Est. completion: Aug 202316 patients
Phase 3Completed
NCT04346108TakedaImmune Globulin Intravenous

A Study of Immune Globulin Subcutaneous (Human), 20% Solution (IGSC, 20%) in Japanese Participants With Primary Immunodeficiency Diseases (PID)

Start: Aug 2020Est. completion: Dec 202117 patients
Phase 3Completed
NCT01736579TakedaImmune Globulin Intravenous

Long-Term Study of IGIV, 10% in Alzheimer´s Disease

Start: Nov 2012Est. completion: Jun 20136 patients
Phase 3Terminated
NCT01524887TakedaImmune Globulin Intravenous

Phase 3 IGIV, 10% in Alzheimer´s Disease

Start: Jan 2012Est. completion: Jul 2013508 patients
Phase 3Terminated
NCT01175213TakedaSC treatment with IGSC, 10% with rHuPH20 followed by SC/IGSC, 10% only

Tolerability and Safety of Immune Globulin Subcutaneous Solution (IGSC) and rHuPH20 in PID

Start: Jul 2010Est. completion: Aug 201366 patients
Phase 3Completed
NCT00814320TakedaImmune Globulin Intravenous

Gammagard Liquid and rHuPH20 in PID

Start: Dec 2008Est. completion: Nov 201089 patients
Phase 3Completed
NCT00157079TakedaImmune Globulin Intravenous

Safety and Efficacy Study of a 10% Intravenous Immune Globulin Solution in Subjects With Primary Immunodeficiency Disorders

Start: Jun 2002Est. completion: Dec 200361 patients
Phase 3Completed
NCT01218438TakedaImmune Globulin Intravenous

Phase 2/3 Study of IGSC, 20% in PIDD

Start: Jan 2013Est. completion: Mar 201586 patients
Phase 2/3Completed
NCT01412385TakedaImmune Globulin Intravenous

Immune Globulin Subcutaenous (Human), 20%

Start: Jun 2011Est. completion: May 201455 patients
Phase 2/3Completed
NCT00546871TakedaImmune Globulin Intravenous

Comparison of Intravenous and Subcutaneous Administration of IGIV, 10% in Primary Immunodeficiency (PID) Subjects

Start: Oct 2007Est. completion: Sep 200949 patients
Phase 2/3Completed

Prevalence of Humoral Dysfunction in Pts With Frequent Exacerbations of COPD, and the Effect of SCIgR for Prevention

Start: Jun 2023Est. completion: Dec 202540 patients
Phase 2Unknown
NCT00162006TakedaImmune Globulin Intravenous

Efficacy and Safety Study of a 10% Triple Virally Reduced Intravenous Immune Globulin Solution in Adult Subjects With Chronic Idiopathic Thrombocytopenic Purpura

Start: Jan 2003Est. completion: Dec 200328 patients
Phase 2Completed
NCT00161993TakedaImmune Globulin Intravenous

Safety, Pharmacokinetic and Efficacy Study of a 10% Triple Virally Reduced Intravenous Immune Globulin Solution in Patients With Primary Immunodeficiency (Hypo- or Agammaglobulinemia)

Start: Jun 2002Est. completion: Sep 200324 patients
Phase 2Completed
NCT00782106TakedaRecombinant human hyaluronidase + immune globulin intravenous

Study to Determine the Dose of Recombinant Human Hyaluronidase Needed to Infuse a Full Dose of IGIV Subcutaneously

Start: Dec 2006Est. completion: Nov 200711 patients
Phase 1/2Completed
NCT06565078TakedaImmune Globulin Subcutaneous

A Database Survey to Evaluate the Safety of Immune Globulin Subcutaneous (Human), 20% Solution in Participants With Primary Immunodeficiency

Start: Feb 2025Est. completion: Jul 2030100 patients
N/ARecruiting

Retrospective, Observational Chart Review Study Conducted in Poland to Document the Management and Clinical Outcome of CUVITRU and HYQVIA in Pediatric Participants (< 18 Years) With Primary Immunodeficiency (PID)

Start: Feb 2021Est. completion: Sep 202196 patients
N/ACompleted

Real-world CANadian CUvitru Non-Interventional Study in Subjects Transitioning From Subcutaneous Immunoglobulin (CANCUN)

Start: Sep 2018Est. completion: Jul 2020126 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 1,435 patients
1 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.