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Postsurgical Pain

7
Pipeline Programs
3
Companies
6
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
2
3
0
2
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Apsen Farmaceutica
Apsen FarmaceuticaBrazil - São Paulo
2 programs
2
APSCTCPhase 31 trial
tramadol and acetaminophenPhase 3
Active Trials
NCT04647435Completed396Est. Oct 2024
Concentric Analgesics
Concentric AnalgesicsCA - San Francisco
4 programs
2
2
CA-008Phase 21 trial
CA-008 5 mgPhase 21 trial
CA-008Phase 1/21 trial
CA-008Phase 1/21 trial
Active Trials
NCT04774328Completed34Est. Jun 2021
NCT04203537Completed193Est. Oct 2020
NCT03731364Completed55Est. May 2019
+1 more trials
UNION therapeutics
UNION therapeuticsDenmark - Hellerup
1 program
1
TetrahydrocannabinolPhase 21 trial
Active Trials
NCT01562483Completed36Est. Jun 2014

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Apsen FarmaceuticaAPSCTC
Concentric AnalgesicsCA-008 5 mg
Concentric AnalgesicsCA-008
UNION therapeuticsTetrahydrocannabinol
Concentric AnalgesicsCA-008
Concentric AnalgesicsCA-008

Clinical Trials (6)

Total enrollment: 768 patients across 6 trials

NCT04647435Apsen FarmaceuticaAPSCTC

Efficacy and Safety of APSCTC for the Treatment of Postsurgical Pain Due to Third Molar Extraction

Start: May 2023Est. completion: Oct 2024396 patients
Phase 3Completed
NCT03789318Concentric AnalgesicsCA-008 5 mg

Study in Subjects Undergoing Complete Abdominoplasty

Start: Dec 2018Est. completion: Jun 201954 patients
Phase 2Completed
NCT03731364Concentric AnalgesicsCA-008

Study of CA-008 (Vocacapsaicin) in Total Knee Arthroplasty

Start: Oct 2018Est. completion: May 201955 patients
Phase 2Completed
NCT01562483UNION therapeuticsTetrahydrocannabinol

The Analgesic Efficacy of Δ9-THC (Namisol®) in Patients With Persistent Postsurgical Abdominal Pain

Start: Oct 2012Est. completion: Jun 201436 patients
Phase 2Completed
NCT04774328Concentric AnalgesicsCA-008

Preliminary Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair

Start: Sep 2020Est. completion: Jun 202134 patients
Phase 1/2Completed
NCT04203537Concentric AnalgesicsCA-008

Study Evaluating the Safety, Efficacy and Pharmacokinetics of CA-008 (Vocacapsaicin)

Start: Dec 2019Est. completion: Oct 2020193 patients
Phase 1/2Completed

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 late-stage (Phase 3) programs, potential near-term approvals
3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.