Polymyalgia Rheumatica

3
Pipeline Programs
2
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
2
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1100%
+ 2 programs with unclassified modality

Competitive Landscape

2 companies ranked by most advanced pipeline stage

CP
Chugai PharmaJapan - Tokyo
2 programs
1
1
TocilizumabPhase 3Monoclonal Antibody1 trial
TCZPhase 21 trial
Active Trials
NCT01713842Completed21Est. Oct 2014
NCT02908217Completed113Est. Nov 2020
Regeneron
RegeneronTARRYTOWN, NY
1 program
1
Sarilumab SAR153191Phase 3

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Chugai PharmaTocilizumab
Chugai PharmaTCZ

Clinical Trials (2)

Total enrollment: 134 patients across 2 trials

Safety and Efficacy of tocilizuMAb Versus Placebo in Polymyalgia rHeumatica With glucocORticoid dEpendence SEMAPHORE

Start: Feb 2017Est. completion: Nov 2020113 patients
Phase 3Completed

Tocilizumab Effect iN pOlymyalgia Rheumatica

Start: Jul 2012Est. completion: Oct 201421 patients
Phase 2Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 late-stage (Phase 3) programs — potential near-term approvals
2 companies competing in this space