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POEMS Syndrome

2
Pipeline Programs
2
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Cell Therapy
1100%
+ 1 programs with unclassified modality

Competitive Landscape

2 companies ranked by most advanced pipeline stage

UNION therapeutics
UNION therapeuticsDenmark - Hellerup
1 program
1
Lenalidomide, DexamethasonePhase 21 trial
Active Trials
NCT01816620Completed41Est. Apr 2017
Novatim Immune Therapeutics
1 program
1
KQ-2003 CAR T-cellsPhase 1Cell Therapy1 trial
Active Trials
NCT06518876Not Yet Recruiting21Est. Dec 2027

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
UNION therapeuticsLenalidomide, Dexamethasone
Novatim Immune TherapeuticsKQ-2003 CAR T-cells

Clinical Trials (2)

Total enrollment: 62 patients across 2 trials

NCT01816620UNION therapeuticsLenalidomide, Dexamethasone

Study to Evaluate Lenalidomide Plus Dexamethasone in Patients With Newly Diagnosed POEMS Syndrome

Start: Mar 2014Est. completion: Apr 201741 patients
Phase 2Completed

A Study of KQ-2003 CAR-T Cell Therapy for Patients With Relapsed or Refractory POEMS Syndrome

Start: Aug 2024Est. completion: Dec 202721 patients
Phase 1Not Yet Recruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

Cell Therapy is the dominant modality (100% of programs)
2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.