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Pharyngitis

4
Pipeline Programs
5
Companies
12
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
0
0
1
1
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 11 programs with unclassified modality

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Medice
MediceGermany - Iserlohn
1 program
1
Benzalkonium Chloride-Benzocaine TopicalPhase 41 trial
Active Trials
NCT03323528Completed321Est. Nov 2017
Pfizer
PfizerNEW YORK, NY
1 program
1
CelecoxibPhase 3Small Molecule1 trial
Active Trials
NCT00402987Completed269Est. Nov 2007
JSC Valenta Pharmaceuticals
2 programs
2
Grammidin neoPhase 11 trial
Grammidin with anesthetic neoPhase 11 trial
Active Trials
NCT06859281Recruiting24Est. Dec 2026
NCT06857890Recruiting24Est. Dec 2026
Boehringer Ingelheim
Boehringer IngelheimINGELHEIM, Germany
7 programs
Ambroxol SprayPHASE_21 trial
Meloxicam lowPHASE_21 trial
AmbroxolPHASE_31 trial
Ambroxol LozengePHASE_31 trial
Ambroxol hydrochloridePHASE_31 trial
+2 more programs
Active Trials
NCT01361802Completed494
NCT02183038Completed390
NCT00525044Completed249Est. Jan 2008
+4 more trials
Jerusalem Pharmaceuticals
Jerusalem PharmaceuticalsIsrael - Ramallah
1 program
rapid streptococcal testingN/A1 trial
Active Trials
NCT00535093Completed7,000Est. Jul 2009

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
MediceBenzalkonium Chloride-Benzocaine Topical
Boehringer IngelheimMeloxicam
Boehringer IngelheimBenzidamine hydrochloride
Boehringer IngelheimAmbroxol
PfizerCelecoxib
Boehringer IngelheimAmbroxol hydrochloride
Boehringer IngelheimAmbroxol Lozenge
Boehringer IngelheimAmbroxol Spray
Boehringer IngelheimMeloxicam low
JSC Valenta PharmaceuticalsGrammidin neo
JSC Valenta PharmaceuticalsGrammidin with anesthetic neo
Jerusalem Pharmaceuticalsrapid streptococcal testing

Clinical Trials (12)

Total enrollment: 10,084 patients across 12 trials

NCT03323528MediceBenzalkonium Chloride-Benzocaine Topical

Safety and Efficacy of a Sore Throat Lozenge DORITHRICIN in Patients With Acute Pharyngitis

Start: Feb 2017Est. completion: Nov 2017321 patients
Phase 4Completed
NCT02229747Boehringer IngelheimMeloxicam

Efficacy and Safety of Meloxicam Suspension Versus Diclofenac Suspension or Nimesulide Suspension in Patients With a Diagnosis of Acute, Non-bacterial Pharyngitis, Pharyngotonsillitis or Laryngitis

Start: Aug 2001128 patients
Phase 4Completed
NCT02178293Boehringer IngelheimBenzidamine hydrochloride

Ketoprofen Lysine Salt as Mouthwash in Acute Phlogosis of the Pharyngeal Cavity Versus Benzidamine Hydrochloride

Start: Sep 1998214 patients
Phase 4Completed
NCT00525044Boehringer IngelheimAmbroxol

Double-blind Trial to Investigate Efficacy and Tolerance of Ambroxol Lozenges 20 mg in Sore Throat

Start: Aug 2007Est. completion: Jan 2008249 patients
Phase 3Completed
NCT00402987PfizerCelecoxib

Testing The Effectiveness Of Celecoxib In Patients With Painful Sore Throat

Start: Dec 2006Est. completion: Nov 2007269 patients
Phase 3Completed
NCT00148499Boehringer IngelheimAmbroxol hydrochloride

Efficacy and Tolerability of Ambroxol Lozenge 20 mf in Relieving Pain of Sore Throat in Pat. With Acute/Viralpharyngitis

Start: Oct 2005Est. completion: Jun 2006751 patients
Phase 3Completed
NCT00144274Boehringer IngelheimAmbroxol Lozenge

Ambroxol Lozenges 20mg in Relieving the Pain of Sore Throat in Adolescent Patients With Acute Viral Pharyngitis

Start: Apr 2005Est. completion: Nov 2005220 patients
Phase 3Completed
NCT01361802Boehringer IngelheimAmbroxol Spray

Ambroxol Spray Sore Throat Study

Start: May 2011494 patients
Phase 2Completed
NCT02183038Boehringer IngelheimMeloxicam low

Efficacy and Safety of Meloxicam vs. Naproxen Sodium in Patients With Acute Non Bacterial Pharyngitis or Pharyngo-tonsillitis

Start: Jul 1998390 patients
Phase 2Completed
NCT06859281JSC Valenta PharmaceuticalsGrammidin neo

Safety, Tolerability, and Pharmacokinetic Profile of Grammidin, a Metered Dose Topical Spray in Healthy Volunteers

Start: Dec 2024Est. completion: Dec 202624 patients
Phase 1Recruiting
NCT06857890JSC Valenta PharmaceuticalsGrammidin with anesthetic neo

Safety, Tolerability, and Pharmacokinetic Profile of Grammidin With Anesthetic, a Metered Dose Topical Spray in Healthy Volunteers

Start: Dec 2024Est. completion: Dec 202624 patients
Phase 1Recruiting
NCT00535093Jerusalem Pharmaceuticalsrapid streptococcal testing

An Assessment of Rapid Streptococcal Tests in Community Clinics in Israel

Start: Oct 2007Est. completion: Jul 20097,000 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs, potential near-term approvals
2 actively recruiting trials targeting 10,084 patients
5 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.