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Pharmacokinetics

80
Pipeline Programs
30
Companies
50
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
78
0
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
660%
Monoclonal Antibody
330%
Peptide
110%
+ 105 programs with unclassified modality

Competitive Landscape

58 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
9 programs
8
1
VoriconazolePhase 2Small Molecule1 trial
AlprazolamPhase 13 trials
CAZ-AVIPhase 11 trial
Nicergoline from ChinaPhase 11 trial
PF-06439535Phase 11 trial
+4 more programs
Active Trials
NCT00877955Withdrawn0Est. Oct 2012
NCT00860119Completed23Est. Oct 2009
NCT00810316Completed24Est. Nov 2008
+8 more trials
Sandoz
SandozAustria - Kundl
1 program
1
LCZ696APhase 21 trial
Active Trials
NCT01569828Completed12Est. Sep 2009
AstraZeneca
AstraZenecaCAMBRIDGE, United Kingdom
9 programs
9
AZD1386Phase 11 trial
AZD6140Phase 11 trial
AZD8566Phase 11 trial
AZD9668Phase 11 trial
AZD9742Phase 11 trial
+4 more programs
Active Trials
NCT00714337Completed12Est. Aug 2008
NCT00721448Completed24Est. Aug 2008
NCT00844103Completed36Est. Apr 2009
+6 more trials
Astellas
AstellasChina - Shenyang
5 programs
5
ASP1707Phase 11 trial
ASP3652Phase 11 trial
ASP3652Phase 11 trial
YM150Phase 11 trial
YM150Phase 11 trial
Active Trials
NCT02175407Completed14Est. Jun 2014
NCT01958047Completed64Est. Sep 2012
NCT01815684Completed26Est. Dec 2012
+2 more trials
GEROPHARM
3 programs
1
GP40221Phase 11 trial
GP30341 capsules 200 mgN/A1 trial
Rinsulin NPHN/A1 trial
Active Trials
NCT05648799Completed246Est. Jul 2022
NCT04501250Completed52Est. May 2018
NCT06497049Completed120Est. May 2024
Allergy Therapeutics
2
MK-2048 High Eudragit Vaginal FilmPhase 11 trial
ledaborbactam etzadroxilPhase 11 trial
VNRX-7145PHASE_11 trial
Active Trials
NCT05527834Completed24Est. Feb 2023
NCT04319718Completed37Est. Oct 2022
NCT06665555Completed34Est. Mar 2025
Orion Pharma
3 programs
3
BAY1841788Phase 11 trial
DexmedetomidinePhase 11 trial
levodopa, carbidopa, entacaponePhase 11 trial
Active Trials
NCT02894385Completed29Est. Dec 2017
NCT00747721Completed13Est. Feb 2009
NCT00693862Completed19Est. May 2008
Bayer
BayerLEVERKUSEN, Germany
3 programs
3
BAY1841788Phase 1
BAY2327949Phase 11 trial
MicrogynonPhase 11 trial
Active Trials
NCT04004195Completed32Est. Jun 2020
NCT02170038Completed16Est. Mar 2015
Orion
3 programs
3
BAY1841788Phase 1
DexmedetomidinePhase 1
levodopa, carbidopa, entacaponePhase 1
MSD
MSDIreland - Ballydine
3 programs
3
BoserolimabPhase 1Monoclonal Antibody1 trial
MK-1064Phase 11 trial
MK-7252Phase 11 trial
Active Trials
NCT03396445Completed182Est. Sep 2024
NCT02549014Completed16Est. Sep 2009
NCT03326986Completed24Est. Dec 2018
Sharp Therapeutics
3
BoserolimabPhase 1Monoclonal Antibody
MK-1064Phase 1
MK-7252Phase 1
Basilea Pharmaceutica
Basilea PharmaceuticaSwitzerland - Allschwil
3 programs
3
VNRX-7145Phase 1
VNRX-7145Phase 1
ledaborbactam etzadroxilPhase 1
Human BioSciences
1
IPM Ring-105Phase 11 trial
Midazolam/Ranitidine/EsomeprazoleN/ASmall Molecule
Active Trials
NCT05041699Completed40Est. Oct 2024
Abbott
AbbottABBOTT PARK, IL
2 programs
2
ABT-335Phase 11 trial
SLV342Phase 11 trial
Active Trials
NCT00681525Completed18
NCT00985478Terminated48Est. Jun 2010
Alkermes
AlkermesDUBLIN 4, Ireland
2 programs
2
ALKS 5461Phase 11 trial
ItraconazolePhase 1Small Molecule1 trial
Active Trials
NCT02068105Completed104Est. Mar 2014
NCT02272764Completed24Est. Nov 2014
Dr. Reddy's Laboratories
2 programs
2
DFD-29Phase 11 trial
DRL_PGPhase 11 trial
Active Trials
NCT05452785Completed24Est. May 2022
NCT02205320Unknown192Est. Sep 2014
Xspray Pharma
2 programs
2
Dasatinib ASDPhase 11 trial
Sorafenib - Period 1Phase 11 trial
Active Trials
NCT05433896Completed17Est. Dec 2020
NCT05967377Completed15Est. Feb 2019
Biolab Pharma
2 programs
2
Isosorbide mononitratePhase 11 trial
eplerenonePhase 11 trial
Active Trials
NCT04729088Withdrawn0Est. Dec 2020
NCT02957435Withdrawn0Est. Dec 2017
Quotient Therapeutics
Quotient TherapeuticsMA - Cambridge
2 programs
2
PF614 capsulePhase 11 trial
PF614 solutionPhase 11 trial
Active Trials
NCT06500793Recruiting30Est. Dec 2026
NCT05090280Completed111Est. Apr 2023
Medigene
2 programs
2
RhuDex®Phase 11 trial
RhuDex®Phase 11 trial
Active Trials
NCT00704119Terminated12Est. Aug 2008
NCT00532012Completed10Est. Nov 2007
Talphera
2 programs
2
Sufentanil NanoTabPhase 11 trial
Treatment A: Sufentanil IVPhase 11 trial
Active Trials
NCT01721070Completed19Est. Dec 2012
NCT01639729Completed25Est. Jul 2012
Nia Therapeutics
Nia TherapeuticsMA - Boston
1 program
1
200 mg resveratrol as JOTROLPhase 11 trial
Active Trials
NCT04668274Completed24Est. May 2021
Zhaoke Ophthalmology
1
Atropine sulfate eye dropsPhase 11 trial
Active Trials
NCT05855018Unknown30Est. Jun 2023
Shionogi
ShionogiJapan - Osaka
1 program
1
CefiderocolPhase 11 trial
Active Trials
NCT05373615Completed14Est. Nov 2024
Journey Medical
1
DFD-29Phase 1
Basking Biosciences
1
DTRI-031Phase 11 trial
Active Trials
NCT05005520Completed46Est. Apr 2022
Alumis
AlumisSOUTH SAN FRANCISCO, CA
1 program
1
ESK-001Phase 13 trials
Active Trials
NCT05966480Active Not Recruiting408Est. Sep 2027
NCT05739435Active Not Recruiting165Est. Dec 2026
NCT05330858Completed14Est. Sep 2022
Galecto Biotech
1
GB1211Phase 11 trial
Active Trials
NCT05747573Completed13Est. Apr 2023
Norgine
1 program
1
NRL972Phase 11 trial
Active Trials
NCT00856752Completed12Est. Aug 2006
DemeRx
1 program
1
NoribogainePhase 11 trial
Active Trials
NCT06480981Completed55Est. Jan 2025

+28 more companies

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
TakedaColchicine
AlumisESK-001
AlumisESK-001
Daiichi SankyoDS-8500a
TevaTV-45070
SandozLCZ696A
PfizerVoriconazole
Johnson & JohnsonJNJ-31001074
RecordatiPasireotide cartridge with reusable ServoPen
Quotient TherapeuticsPF614 capsule
Allergy Therapeuticsledaborbactam etzadroxil
DemeRxNoribogaine
Zenshine PharmaceuticalsZX-7101A
GEROPHARMGP40221
PfizerRosuvastatin

Showing 15 of 50 trials with date data

Clinical Trials (50)

Total enrollment: 3,225 patients across 50 trials

Healthy and Renal Impairment Study of Colcrys (Colchicine, USP)

Start: May 2010Est. completion: Feb 201140 patients
Phase 4Completed

Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus

Start: Jun 2023Est. completion: Sep 2027408 patients
Phase 2Active Not Recruiting

Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis

Start: Jan 2023Est. completion: Dec 2026165 patients
Phase 2Active Not Recruiting

A Study of DS-8500a in Japanese Subjects With Type 2 Diabetes Mellitus Receiving Sitagliptin

Start: Jan 2016Est. completion: Oct 201685 patients
Phase 2Completed

A Study to Evaluate the Safety and Efficacy of Topically Applied TV 45070 Ointment in Patients With Postherpetic Neuralgia (PHN)

Start: Feb 2015Est. completion: May 2017300 patients
Phase 2Completed

Multiple Dose Pharmacokinetics of LCZ696 and Its Metabolites in Subjects With Severe Renal Impairment vs. Matched Healthy Subjects With Normal Renal Function

Start: Mar 2009Est. completion: Sep 200912 patients
Phase 2Completed
NCT00556998PfizerVoriconazole

A Multiple-Dose Study To Evaluate The Pharmacokinetics And Safety Of Voriconazole In Immunocompromised Adolescents

Start: Jun 2008Est. completion: Dec 200926 patients
Phase 2Completed

A Study to Evaluate the Pharmacokinetic Drug Interaction Between Multiple Doses of JNJ-31001074 and a Single Dose of an Oral Contraceptive Containing Ethinyl Estradiol and Levonorgestrel in Women

Est. completion: Mar 20110
Phase 1Withdrawn
NCT07312643RecordatiPasireotide cartridge with reusable ServoPen

Study in Healthy Subjects to Investigate the Relative Bioavailability and Safety of Pasireotide After Single Subcutaneous Dose Administration Using a Reusable ServoPen With Cartridge as Compared to Administration Using a Syringe Drawn From an Ampule

Start: Dec 2025Est. completion: Feb 202640 patients
Phase 1Completed

Single Dose Study, Pharmacokinetics of Oxycodone and PF614 Co-Administered With Nafamostat (PF614-MPAR-102)

Start: Nov 2024Est. completion: Dec 202630 patients
Phase 1Recruiting
NCT06665555Allergy Therapeuticsledaborbactam etzadroxil

Plasma and Intrapulmonary Pharmacokinetics of Ceftibuten and Ledaborbactam in Healthy Male and Female Participants 18 to ≤55 Years of Age

Start: Nov 2024Est. completion: Mar 202534 patients
Phase 1Completed

Multiple Ascending Dose Noribogaine PK/PD in Healthy Volunteers

Start: Jun 2024Est. completion: Jan 202555 patients
Phase 1Completed

A Study to Assess the Effect of Itraconazole Capsules on the Pharmacokinetics of ZX-7101A Tablets in Healthy Adult Subjects in China

Start: Jul 2023Est. completion: Jan 202416 patients
Phase 1Completed

Open Randomized Study of Comparative Pharmacokinetics and Biosimilarity of GP40221 (GEROPHARM LLC, Russia) and Ozempic®.

Start: Jun 2023Est. completion: May 2024120 patients
Phase 1Completed
NCT05898672PfizerRosuvastatin

A Study to Learn About the Study Medicine Called Nirmatrelvir/Ritonavir in People Who Are Healthy Volunteers Co-administered the Medicine Rosuvastatin

Start: Jun 2023Est. completion: Aug 202312 patients
Phase 1Completed
NCT05855018Zhaoke OphthalmologyAtropine sulfate eye drops

A Study of Atropine Sulfate in Healthy Chinese Volunteers

Start: May 2023Est. completion: Jun 202330 patients
Phase 1Unknown

Hutrukin to Analyze Safety and PK in Healthy Volunteers

Start: Apr 2023Est. completion: Apr 202424 patients
Phase 1Completed

A Study to Compare Pharmacokinetics of GB1211

Start: Jan 2023Est. completion: Apr 202313 patients
Phase 1Completed

The Absorption, Metabolism and Excretion of [14C]APG-2575 in Healthy Subjects

Start: Sep 2022Est. completion: Apr 20236 patients
Phase 1Completed

Food Effect on Ceftibuten/VNRX-7145 in Healthy Participants

Start: Sep 2022Est. completion: Feb 202324 patients
Phase 1Completed
NCT05569278GE HealthCareGE200486 0.5M Injection

Safety and Pharmacokinetics of GEH200486 in Healthy Volunteers

Start: Aug 2022Est. completion: Nov 202215 patients
Phase 1Completed

Cefiderocol Plasma Concentrations in Patients Receiving Renal Replacement Therapy

Start: Jul 2022Est. completion: Nov 202414 patients
Phase 1Completed
NCT05469854Cinclus PharmaLinaprazan glurate

A Study to Investigate the Pharmacokinetics and ECG Effects of Linaprazan Glurate

Start: Jul 2022Est. completion: Dec 2024113 patients
Phase 1Unknown

PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel

Start: Jun 2022Est. completion: Oct 202440 patients
Phase 1Completed

A Comparative Bioavailability Study of DFD-29 Capsules 40 mg Versus SOLODYN® Tablets 105 mg, Under Fasting & Fed Conditions in Healthy Adult Human Subjects

Start: May 2022Est. completion: May 202224 patients
Phase 1Completed

Relative Bioavailability of ESK-001 Tablet Versus Liquid in Healthy Participants

Start: Mar 2022Est. completion: Sep 202214 patients
Phase 1Completed

Natrunix Safety PK Study in Healthy Volunteers

Start: Jan 2022Est. completion: Jun 202224 patients
Phase 1Unknown

Pharmacokinetics of Oxycodone and PF614 Co-Administered with Nafamostat (PF614-MPAR-101)

Start: Dec 2021Est. completion: Apr 2023111 patients
Phase 1Completed

Study of DTRI-031 in Healthy Volunteers

Start: Oct 2021Est. completion: Apr 202246 patients
Phase 1Completed

Randomized Crossover of SVG101(Dispersible Tab. of Everolimus) and Afinitor 5mg in Healthy Adults

Start: Jul 2021Est. completion: Feb 202226 patients
Phase 1Completed

A SINGLE-DOSE, 2-ARM, PHARMACOKINETIC STUDY OF PF-06439535 (CN) AND EUROPEAN UNION SOURCED BEVACIZUMAB IN CHINESE HEALTHY MALE VOLUNTEERS

Start: Jan 2021Est. completion: Jul 20210
Phase 1Withdrawn
NCT04668274Nia Therapeutics200 mg resveratrol as JOTROL

JOTROL PK, Safety, and Food Effect Assessment

Start: Jan 2021Est. completion: May 202124 patients
Phase 1Completed
NCT04729088Biolab PharmaIsosorbide mononitrate

Pharmacokinetics Trial of Isosorbide Mononitrate 0.5% Gel for Intra Anal Application in Healthy Subjects

Start: Dec 2020Est. completion: Dec 20200
Phase 1Withdrawn

Evaluating the Effects of Omeprazole on the Pharmacokinetics of XS004 (Dasatinib) Tablets in Healthy Adult Subjects Under Fasting Conditions

Start: Nov 2020Est. completion: Dec 202017 patients
Phase 1Completed
NCT04319718Allergy TherapeuticsMK-2048 High Eudragit Vaginal Film

Safety and Pharmacokinetics of Two Vaginal Film Formulations Containing the Integrase Inhibitor MK-2048

Start: Aug 2020Est. completion: Oct 202237 patients
Phase 1Completed

A Two-part Pharmacokinetic Study of PXS-5382A in Healthy Adult Males

Start: Dec 2019Est. completion: Jun 202018 patients
Phase 1Completed
NCT04176367PfizerNicergoline from China

An Bioequivalence Study Comparing Nicergoline 10 mg Tablet Manufactured in China With Nicergoline 10 mg Tablet Manufactured in Italy Under Fasted and Fed Conditions in Healthy Chinese Participants

Start: Dec 2019Est. completion: Sep 202040 patients
Phase 1Completed

Study to Evaluate the Effect of SCY-078 (Ibrexafungerp) on the PK of Pravastatin in Healthy Subjects

Start: Nov 2019Est. completion: Dec 201928 patients
Phase 1Completed

Study to Evaluate the Effect of SCY-078 on the PK of Dabigatran in Healthy Subjects

Start: Sep 2019Est. completion: Jan 202036 patients
Phase 1Completed

Study to Investigate Safety, Absorption, Elimination, and Drug Effect of BAY2327949 in Participants With Different Renal Function Status

Start: Jul 2019Est. completion: Jun 202032 patients
Phase 1Completed
NCT05967377Xspray PharmaSorafenib - Period 1

Evaluating the Pharmacokinetic Parameters and Relative Bioavailability of Sorafenib (XS005) in Healthy Male Subjects

Start: Nov 2018Est. completion: Feb 201915 patients
Phase 1Completed

Food Effects on Milademetan Pharmacokinetics in Healthy Participants

Start: Aug 2018Est. completion: Sep 201818 patients
Phase 1Completed

Pharmacokinetics (PK) Drug Interaction Study of Milademetan and Itraconazole or Posaconazole in Healthy Participants

Start: Jul 2018Est. completion: Oct 201836 patients
Phase 1Completed

VNRX-5133 With VNRX-5022 in Subjects With Varying Degrees of Renal Impairment

Start: Apr 2018Est. completion: Nov 201833 patients
Phase 1Completed

Study to Evaluate the Effect of Coadministered Erythromycin on the Pharmacokinetics and Safety of Padsevonil

Start: Mar 2018Est. completion: Aug 201828 patients
Phase 1Completed
NCT03396445MSDBoserolimab

Study of Boserolimab (MK-5890) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Adults With Advanced Solid Tumors (MK-5890-001)

Start: Feb 2018Est. completion: Sep 2024182 patients
Phase 1Completed
NCT03324061Eagle PharmaceuticalsFulvestrant for Injectable Suspension

Study to Evaluate the Safety, Tolerability, and PK of Fulvestrant After IM Administration

Start: Nov 2017Est. completion: Jul 2018600 patients
Phase 1Completed

Safety, Tolerability and Pharmacokinetics Study of MK-7252 in Healthy Adult Participants (MK-7252-001)

Start: Nov 2017Est. completion: Dec 201824 patients
Phase 1Completed

Phase I, Pharmacokinetic, Safety and Tolerability Study in Healthy Volunteers

Start: Oct 2017Est. completion: Dec 2018190 patients
Phase 1Completed

Pharmacokinetics Study of Eplerenone Coated Tablets

Start: Jul 2017Est. completion: Dec 20170
Phase 1Withdrawn

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 3,225 patients
30 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.