Skip to main content

Peripheral Vascular Disease

4
Pipeline Programs
19
Companies
25
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
2
2
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

17 companies ranked by most advanced pipeline stage

Otsuka
OtsukaJapan - Tokushima
1 program
1
Levocarnitine tartratePhase 41 trial
Active Trials
NCT00822172Completed164Est. Dec 2010
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
1 program
1
Levocarnitine tartratePhase 4
Abbott
AbbottABBOTT PARK, IL
6 programs
2
Absolute Pro™ Peripheral Self-Expanding Stent SystemPhase 31 trial
Omnilink Elite™ Peripheral Balloon-Expandable Stent SystemPhase 31 trial
Angio-Seal Evolution Device RegistryN/A1 trial
IDEV SUPERA StentN/A1 trial
SUPERA® Nitinol Stent SystemN/A1 trial
+1 more programs
Active Trials
NCT00817349Completed1,004Est. Apr 2010
NCT01667393Withdrawn0Est. Jan 2013
NCT00933270Completed325Est. Jul 2014
+3 more trials
Medtronic
MedtronicNJ - Phillipsburg
4 programs
Assurant® Cobalt Iliac Stent SystemN/A1 trial
Complete SE Iliac StentN/A1 trial
Complete SE Vascular Stent SystemN/A1 trial
Medtronic HawkOne® or TurboHawk™N/A1 trial
Active Trials
NCT00753337Completed123Est. Sep 2013
NCT00730730Completed50Est. Aug 2012
NCT00814970Completed196Est. Dec 2013
+1 more trials
Boston Scientific
Boston ScientificCA - Valencia
2 programs
Conventional angioplasty balloonN/A1 trial
Registry of AngioJet Use in the Peripheral Vascular SystemN/A1 trial
Active Trials
NCT00827853Completed90Est. Feb 2012
NCT01086215Completed500Est. Sep 2013
Innovation Pharmaceuticals
1 program
Active FlowOx™N/A1 trial
Active Trials
NCT04100681Terminated16Est. May 2020
Elixir Medical
Elixir MedicalCA - Milpitas
1 program
Akesys Prava ScaffoldN/A1 trial
Active Trials
NCT02869087Completed21Est. Apr 2021
Sensome
SensomeFrance - Massy
1 program
Clotild Smart Guidewire SystemN/A1 trial
Active Trials
NCT06112054Completed19Est. Aug 2024
Elutia
ElutiaSILVER SPRING, MD
1 program
CorMatrix ECM for Vascular RepairN/A1 trial
Active Trials
NCT02418156Completed38Est. Mar 2018
Genentech
GenentechCA - Oceanside
1 program
Elecsys®proBNPN/A1 trial
Active Trials
NCT00519961Unknown1,800Est. Sep 2010
Integra LifeSciences
Integra LifeSciencesAustralia - Clayton
1 program
Gelfoam/ThrombinN/A1 trial
Active Trials
NCT00439309Terminated69Est. May 2008
Terumo Medical
Terumo MedicalGermany - Leverkusen
1 program
Misago™ Self-Expanding Stent SystemN/A1 trial
Active Trials
NCT01118117Completed276Est. Apr 2016
Philips
PhilipsNetherlands - Amsterdam
1 program
Tack-It Endovascular StaplerN/A1 trial
Active Trials
NCT01663818Completed138Est. Oct 2015
Pfizer
PfizerNEW YORK, NY
1 program
lifestyle, PTAN/A1 trial
Active Trials
NCT00222196Completed200Est. Dec 2004
Medica Corp
Medica CorpMA - Bedford
1 program
mechanical anastomosis without sutureN/A1 trial
Active Trials
NCT01514916Unknown30
United Therapeutics
United TherapeuticsMD - Silver Spring
1 program
RemodulinPHASE_2_31 trial
Active Trials
NCT00067041Terminated30Est. Dec 2003
Bracco
BraccoItaly - Milan
1 program
MultiHancePHASE_31 trial
Active Trials
NCT00408083Completed100Est. Dec 2008

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
OtsukaLevocarnitine tartrate
AbbottAbsolute Pro™ Peripheral Self-Expanding Stent System
AbbottOmnilink Elite™ Peripheral Balloon-Expandable Stent System
BraccoMultiHance
United TherapeuticsRemodulin
SensomeClotild Smart Guidewire System
Innovation PharmaceuticalsActive FlowOx™
Elixir MedicalAkesys Prava Scaffold
MedtronicMedtronic HawkOne® or TurboHawk™
ElutiaCorMatrix ECM for Vascular Repair
AbbottIDEV SUPERA Stent
PhilipsTack-It Endovascular Stapler
Terumo MedicalMisago™ Self-Expanding Stent System
Boston ScientificRegistry of AngioJet Use in the Peripheral Vascular System
AbbottSUPERA® Nitinol Stent System

Showing 15 of 24 trials with date data

Clinical Trials (25)

Total enrollment: 5,760 patients across 25 trials

NCT00822172OtsukaLevocarnitine tartrate

Evaluation of Cilostazol in Combination With L-Carnitine

Start: Sep 2008Est. completion: Dec 2010164 patients
Phase 4Completed
NCT00844532AbbottAbsolute Pro™ Peripheral Self-Expanding Stent System

Trial to Evaluate the Safety & Efficacy of the Absolute Pro™ Peripheral Self-Expanding Stent System in Subjects With Atherosclerotic de Novo or Restenotic Lesions in the Native Common Iliac Artery and/or Native External Iliac Artery.

Start: Mar 2009Est. completion: Jun 2014151 patients
Phase 3Completed
NCT01396525AbbottOmnilink Elite™ Peripheral Balloon-Expandable Stent System

Trial to Evaluate the Safety & Efficacy of the Omnilink Elite™ Peripheral Balloon-Expandable Stent System in Subjects With Atherosclerotic de Novo or Restenotic Lesions in the Native Common Iliac Artery and/or Native External Iliac Artery

Start: Mar 2009Est. completion: Jun 2014153 patients
Phase 3Completed

Crossover Study With MultiHance vs a Comparator for Peripheral MRA

Start: Dec 2006Est. completion: Dec 2008100 patients
Phase 3Completed

Effects of Remodulin in Patients With Critical Limb Ischemia Following a Vein Bypass Graft

Start: Mar 2003Est. completion: Dec 200330 patients
Phase 2/3Terminated
NCT01514916Medica Corpmechanical anastomosis without suture

New Anastomotic Device for End to End Vascular Anastomosis in the Treatment of Peripheral Vascular Disease

30 patients
N/AUnknown
NCT06112054SensomeClotild Smart Guidewire System

Impedance Sensor Evaluated in Peripheral Artery Disease for Tissue Detection

Start: Nov 2023Est. completion: Aug 202419 patients
N/ACompleted

Intermittent Negative Pressure; Impact on Peripheral Artery Disease and Intermittent Claudication

Start: Aug 2019Est. completion: May 202016 patients
N/ATerminated
NCT02869087Elixir MedicalAkesys Prava Scaffold

The DESappear Study: Drug Eluting Scaffold

Start: Oct 2016Est. completion: Apr 202121 patients
N/ACompleted
NCT02850107MedtronicMedtronic HawkOne® or TurboHawk™

DiRectional AthErectomy + Drug CoAted BaLloon to Treat Long, CalcifIed FemoropopliTeal ArterY Lesions

Start: Jun 2016Est. completion: Jun 2020102 patients
N/ACompleted
NCT02418156ElutiaCorMatrix ECM for Vascular Repair

A Study on the Use of CorMatrix® ECM® for Femoral Arterial Reconstruction

Start: May 2015Est. completion: Mar 201838 patients
N/ACompleted
NCT01667393AbbottIDEV SUPERA Stent

Popliteal Artery of Treatment With Balloon Angioplasty vs. SUPERA VERITAS Peripheral Stent System

Start: Jan 2013Est. completion: Jan 20130
N/AWithdrawn
NCT01663818PhilipsTack-It Endovascular Stapler

Tack Optimized Balloon Angioplasty (TOBA) Study

Start: Aug 2012Est. completion: Oct 2015138 patients
N/ACompleted
NCT01118117Terumo MedicalMisago™ Self-Expanding Stent System

A Multi-center Clinical Trial of the Misago™ Self-Expanding Stent System for Superficial Femoral Artery

Start: Jul 2010Est. completion: Apr 2016276 patients
N/ACompleted
NCT01086215Boston ScientificRegistry of AngioJet Use in the Peripheral Vascular System

Registry of AngioJet Use in the Peripheral Vascular System

Start: Jan 2010Est. completion: Sep 2013500 patients
N/ACompleted
NCT00933270AbbottSUPERA® Nitinol Stent System

Comparison of the SUpera® PERipheral System in the Superficial Femoral Artery

Start: Jul 2009Est. completion: Jul 2014325 patients
N/ACompleted
NCT00827853Boston ScientificConventional angioplasty balloon

Study Comparing Two Methods of Expanding Stents Placed in Legs of Diabetics With Peripheral Vascular Disease

Start: Nov 2008Est. completion: Feb 201290 patients
N/ACompleted
NCT00814970MedtronicComplete SE Vascular Stent System

The Complete® SE SFA Study for the Treatment of SFA/PPA Lesions

Start: Nov 2008Est. completion: Dec 2013196 patients
N/ACompleted
NCT00753337MedtronicAssurant® Cobalt Iliac Stent System

The ACTIVE (Use of the Assurant® Cobalt Iliac Stent System in the Treatment of Iliac Vessel Disease) Study

Start: Oct 2008Est. completion: Sep 2013123 patients
N/ACompleted
NCT00817349AbbottAngio-Seal Evolution Device Registry

Angio-Seal Evolution Device Registry

Start: Jul 2008Est. completion: Apr 20101,004 patients
N/ACompleted
NCT00730730MedtronicComplete SE Iliac Stent

The Complete® Self-Expanding Stent and Stent Delivery System Registry

Start: Nov 2007Est. completion: Aug 201250 patients
N/ACompleted

Study to Evaluate Safety & Effectiveness of Vascular Sealant System

Start: Apr 2007Est. completion: May 200869 patients
N/ATerminated
NCT00519961GenentechElecsys®proBNP

A Prospective Study to Assess the Screening Value of N-terminal Pro-B-type Natriuretic Peptide (NT-proBNP) for the Identification of Patients That Benefit From Additional Cardiac Testing Prior to Vascular Surgery

Start: Feb 2007Est. completion: Sep 20101,800 patients
N/AUnknown
NCT00736086AbbottVessel Closure

RISE: A Clinical Evaluation of the StarClose™ Vascular Closure System

Start: Mar 2006Est. completion: Dec 2006165 patients
N/ACompleted
NCT00222196Pfizerlifestyle, PTA

Oslo Balloon Angioplasty Versus Conservative Treatment

Start: Nov 2000Est. completion: Dec 2004200 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 late-stage (Phase 3) programs, potential near-term approvals
19 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.