Periodontal Disease

Pipeline Programs

Companies

Clinical Trials

1 recruiting

Approved Products

Pipeline by Development Stage

Preclinical

Phase 1

Phase 1/2

Phase 2

Phase 2/3

Phase 3

On Market

Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Pre

P1/2

P2/3

Mkt

Noveome BiotherapeuticsPA - Pittsburgh

1 program

ST266Phase 21 trial

Active Trials

NCT02761993Completed151Est. Oct 2017

BioTherapeutics IncVA - Blacksburg

1 program

ST266Phase 2

SanofiPARIS, France

1 program

Investigational ProcedureN/A2 trials

Active Trials

NCT07536048Active Not Recruiting100Est. May 2027

NCT06582056Completed226Est. Sep 2025

Johnson & JohnsonNEW BRUNSWICK, NJ

1 program

Periodontal and Periapical Inflammation and PregnancyN/A1 trial

Active Trials

NCT00490165Completed30Est. Dec 2011

Pierre FabreFrance - Aignan

1 program

Test interdental brushN/A1 trial

Active Trials

NCT07575997Recruiting88Est. Jun 2027

BiocorpFrance - Issoire

1 program

trochesN/A1 trial

Active Trials

NCT04873505Completed50Est. Apr 2022

Trial Timeline

Clinical trial activity over time

2021

2022

2023

2024

2025

2026

2027

Noveome BiotherapeuticsST266

SanofiInvestigational Procedure

Pierre FabreTest interdental brush

SanofiInvestigational Procedure

Biocorptroches

Johnson & JohnsonPeriodontal and Periapical Inflammation and Pregnancy

Clinical Trials (6)

Total enrollment: 645 patients across 6 trials

NCT02761993 Noveome BiotherapeuticsST266

Safety, Efficacy and Treatment Regimen Study of ST266 in Subjects With Moderate to Severe Periodontitis

Start: Apr 2016Est. completion: Oct 2017151 patients

Phase 2Completed

NCT07536048 SanofiInvestigational Procedure

A Longitudinal Study of Epstein-Barr Virus (EBV) Reactivation in Adults Aged 18 to 29 Years

Start: Apr 2026Est. completion: May 2027100 patients

N/AActive Not Recruiting

NCT07575997 Pierre FabreTest interdental brush

Comparison Between Different Interdental Brushes in Adults With Periodontal Disease.

Start: Apr 2026Est. completion: Jun 202788 patients

N/ARecruiting

NCT06582056 SanofiInvestigational Procedure

Study on Biomarkers of Periodontitis and Type 2 Diabetes Mellitus in Males and Females 30 - 70 Years of Age

Start: Oct 2024Est. completion: Sep 2025226 patients

N/ACompleted

NCT04873505 Biocorptroches

Functional Validation of Lactobacillus Containing Oral Tablet

Start: Oct 2020Est. completion: Apr 202250 patients

N/ACompleted

NCT00490165 Johnson & JohnsonPeriodontal and Periapical Inflammation and Pregnancy

Periodontal and Periapical Inflammation and Pregnancy

Start: Mar 2007Est. completion: Dec 201130 patients

N/ACompleted

Phase Legend

Preclinical— Lab & animal studies

Phase 1— Safety & dosing

Phase 2— Efficacy testing

Phase 3— Large-scale trials

On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 645 patients

6 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.