Pelvic Organ Prolapse

2
Pipeline Programs
7
Companies
10
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
2
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

5 companies ranked by most advanced pipeline stage

C
ColoplastAustralia - Mulgrave
6 programs
1
Axis Dermis biologic mesh repair for pelvic organ prolapsePhase 41 trial
AxisN/A1 trial
Exair Prolapse Repair SystemN/A1 trial
Exair Transvaginal MeshN/A1 trial
Restorelle Direct Fix AN/A1 trial
+1 more programs
Active Trials
NCT01541748CompletedEst. Nov 2018
NCT02162628TerminatedEst. Dec 2015
NCT03271294CompletedEst. Aug 2015
+3 more trials
Astellas
AstellasChina - Shenyang
1 program
1
SolifenacinPhase 41 trial
Active Trials
NCT01092624Terminated94Est. Oct 2011
Olympus
OlympusPA - Center Valley
1 program
3D mode of the 3D Laparoscopic Video SystemN/A1 trial
Active Trials
NCT02258230Completed194Est. Mar 2018
Providence Therapeutics
1 program
Laparoscopic sacral hysteropexyN/A1 trial
Active Trials
NCT01377142CompletedEst. Dec 2015
Francis Medical
Francis MedicalMN - Maple Grove
1 program
sacrospinous Ligament FixationN/A1 trial
Active Trials
NCT03782285UnknownEst. Sep 2019

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
ColoplastAxis Dermis biologic mesh repair for pelvic organ prolapse
AstellasSolifenacin
Francis Medicalsacrospinous Ligament Fixation
Coloplastpelvic organ prolapse repair
Olympus3D mode of the 3D Laparoscopic Video System
ColoplastRestorelle Direct Fix A
ColoplastExair Prolapse Repair System
ColoplastExair Transvaginal Mesh
ColoplastAxis
Providence TherapeuticsLaparoscopic sacral hysteropexy

Clinical Trials (10)

Total enrollment: 288 patients across 10 trials

NCT06263985ColoplastAxis Dermis biologic mesh repair for pelvic organ prolapse

Axis(TM) Solvent-dehydrate Dermal Allograft in the Treatment of Pelvic Organ Prolapse.

Start: Nov 2021Est. completion: May 2025
Phase 4Unknown
NCT01092624AstellasSolifenacin

Clinical Trial of Solifenacin Versus Placebo Plus Pessary for Women With Vaginal Prolapse

Start: Mar 2010Est. completion: Oct 201194 patients
Phase 4Terminated
NCT03782285Francis Medicalsacrospinous Ligament Fixation

Sacrospinous Ligament Fixation With Conventional Surgical Instruments in Chinese Apical Prolapse Female Patients

Start: Nov 2018Est. completion: Sep 2019
N/AUnknown
NCT03098641Coloplastpelvic organ prolapse repair

Smartmesh Technology in Pelvic Floor Repair Procedures

Start: May 2017Est. completion: Sep 2017
N/ACompleted
NCT02258230Olympus3D mode of the 3D Laparoscopic Video System

Laparoscopic Three-dimensional Versus Two-dimensional Sacral Colpopexy and Paravaginal Repair

Start: Dec 2014Est. completion: Mar 2018194 patients
N/ACompleted
NCT02162615ColoplastRestorelle Direct Fix A

Restorelle® Mesh Versus Native Tissue Repair for Prolapse

Start: Aug 2014Est. completion: Nov 2021
N/ACompleted
NCT02162628ColoplastExair Prolapse Repair System

Exair® Versus Native Tissue Repair for Prolapse

Start: Aug 2014Est. completion: Dec 2015
N/ATerminated
NCT03271294ColoplastExair Transvaginal Mesh

Prospective Performance Analysis of the Exair(TM) Prolapse Repair System in the Treatment of Pelvic Organ Prolapse

Start: Apr 2013Est. completion: Aug 2015
N/ACompleted
NCT01541748ColoplastAxis

Axis™ Allograft Dermis for Female Pelvic Floor Repair: a Prospective Post Market Study

Start: Nov 2011Est. completion: Nov 2018
N/ACompleted
NCT01377142Providence TherapeuticsLaparoscopic sacral hysteropexy

Vaginal Uphold Hysteropexy and Laparoscopic Sacral Hysteropexy for the Treatment of Uterovaginal Pelvic Organ Prolapse

Start: Jun 2011Est. completion: Dec 2015
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

7 companies competing in this space