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Patients Receiving Mismatched Allogeneic HCT

2
Pipeline Programs
2
Companies
6
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Neovii Biotech
Neovii BiotechGermany - Grafelfing
1 program
1
immunosuppressionPhase 21 trial
Active Trials
NCT01582048Terminated9Est. Aug 2016
Pfizer
PfizerNEW YORK, NY
1 program
1
immunosuppressionPhase 25 trials
Active Trials
NCT01166724Terminated12Est. Dec 2014
NCT00555373Completed52Est. Nov 2012
NCT02117596Completed52Est. Nov 2012
+2 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Pfizerimmunosuppression
Pfizerimmunosuppression
Pfizerimmunosuppression
Neovii Biotechimmunosuppression
Pfizerimmunosuppression
Pfizerimmunosuppression

Clinical Trials (6)

Total enrollment: 301 patients across 6 trials

NCT00812123Pfizerimmunosuppression

Calcineurin Free Immunosuppression in Renal Transplant Recipients

Start: Jan 2001Est. completion: Jul 2005127 patients
Phase 4Completed
NCT01166724Pfizerimmunosuppression

Renal Allograft Function and Histology Following Switching From A Tacrolimus to Sirolimus (SRL)-Based Immunosuppression-

Start: Jul 2010Est. completion: Dec 201412 patients
Phase 3Terminated
NCT00189202Pfizerimmunosuppression

Efficacy of Sirolimus-Based, Steroid Avoidance Immunosuppression African Americans

Start: Aug 2004Est. completion: Jul 200849 patients
Phase 2/3Completed
NCT01582048Neovii Biotechimmunosuppression

Multicenter Study of Peritransplantation Immunosuppression for Mismatched Hematopoietic Cell Transplantation After Reduced Intensity Conditioning

Start: Apr 2012Est. completion: Aug 20169 patients
Phase 2Terminated
NCT00555373Pfizerimmunosuppression

Pediatric Kidney Transplant Study of Sirolimus, Mycophenolate Mofetil, and Corticosteroids vs Calcineurin Inhibitor Based Immunosuppression

Start: Nov 2007Est. completion: Nov 201252 patients
N/ACompleted
NCT02117596Pfizerimmunosuppression

Calcineurin Inhibitor Based Immunosuppression Withdrawal

Start: Nov 2007Est. completion: Nov 201252 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.