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Patients Receiving Mismatched Allogeneic HCT

2
Pipeline Programs
2
Companies
6
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
1 program
1
immunosuppressionPhase 25 trials
Active Trials
NCT01166724Terminated12Est. Dec 2014
NCT00555373Completed52Est. Nov 2012
NCT02117596Completed52Est. Nov 2012
+2 more trials
Neovii Biotech
Neovii BiotechGermany - Grafelfing
1 program
1
immunosuppressionPhase 21 trial
Active Trials
NCT01582048Terminated9Est. Aug 2016

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Pfizerimmunosuppression
Pfizerimmunosuppression
Pfizerimmunosuppression
Neovii Biotechimmunosuppression
Pfizerimmunosuppression
Pfizerimmunosuppression

Clinical Trials (6)

Total enrollment: 301 patients across 6 trials

NCT00812123Pfizerimmunosuppression

Calcineurin Free Immunosuppression in Renal Transplant Recipients

Start: Jan 2001Est. completion: Jul 2005127 patients
Phase 4Completed
NCT01166724Pfizerimmunosuppression

Renal Allograft Function and Histology Following Switching From A Tacrolimus to Sirolimus (SRL)-Based Immunosuppression-

Start: Jul 2010Est. completion: Dec 201412 patients
Phase 3Terminated
NCT00189202Pfizerimmunosuppression

Efficacy of Sirolimus-Based, Steroid Avoidance Immunosuppression African Americans

Start: Aug 2004Est. completion: Jul 200849 patients
Phase 2/3Completed
NCT01582048Neovii Biotechimmunosuppression

Multicenter Study of Peritransplantation Immunosuppression for Mismatched Hematopoietic Cell Transplantation After Reduced Intensity Conditioning

Start: Apr 2012Est. completion: Aug 20169 patients
Phase 2Terminated
NCT00555373Pfizerimmunosuppression

Pediatric Kidney Transplant Study of Sirolimus, Mycophenolate Mofetil, and Corticosteroids vs Calcineurin Inhibitor Based Immunosuppression

Start: Nov 2007Est. completion: Nov 201252 patients
N/ACompleted
NCT02117596Pfizerimmunosuppression

Calcineurin Inhibitor Based Immunosuppression Withdrawal

Start: Nov 2007Est. completion: Nov 201252 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.