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Patients Receiving Mismatched Allogeneic HCT

2
Pipeline Programs
2
Companies
8
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
1 program
1
immunosuppressionPhase 25 trials
Active Trials
NCT01582048Terminated9Est. Aug 2016
NCT01166724Terminated12Est. Dec 2014
NCT02117596Completed52Est. Nov 2012
+2 more trials
Neovii Biotech
Neovii BiotechGermany - Grafelfing
1 program
1
immunosuppressionPhase 2

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Pfizerimmunosuppression
Pfizerimmunosuppression
Pfizerimmunosuppression
Pfizerimmunosuppression
Pfizerimmunosuppression
Pfizerimmunosuppression
Pfizerimmunosuppression
Pfizerimmunosuppression

Clinical Trials (8)

Total enrollment: 694 patients across 8 trials

NCT00275535Pfizerimmunosuppression

The Comparison of Tacrolimus and Sirolimus Immunosuppression Based Drug Regimens in Kidney Transplant Recipients

Start: Apr 2001Est. completion: Dec 2008165 patients
Phase 4Completed
NCT00812123Pfizerimmunosuppression

Calcineurin Free Immunosuppression in Renal Transplant Recipients

Start: Jan 2001Est. completion: Jul 2005127 patients
Phase 4Completed
NCT01166724Pfizerimmunosuppression

Renal Allograft Function and Histology Following Switching From A Tacrolimus to Sirolimus (SRL)-Based Immunosuppression-

Start: Jul 2010Est. completion: Dec 201412 patients
Phase 3Terminated
NCT00140543Pfizerimmunosuppression

European Trial of Immunosuppression in SPK Tx

Start: Feb 2002Est. completion: Sep 2005228 patients
Phase 3Completed
NCT00189202Pfizerimmunosuppression

Efficacy of Sirolimus-Based, Steroid Avoidance Immunosuppression African Americans

Start: Aug 2004Est. completion: Jul 200849 patients
Phase 2/3Completed
NCT01582048Pfizerimmunosuppression

Multicenter Study of Peritransplantation Immunosuppression for Mismatched Hematopoietic Cell Transplantation After Reduced Intensity Conditioning

Start: Apr 2012Est. completion: Aug 20169 patients
Phase 2Terminated
NCT00555373Pfizerimmunosuppression

Pediatric Kidney Transplant Study of Sirolimus, Mycophenolate Mofetil, and Corticosteroids vs Calcineurin Inhibitor Based Immunosuppression

Start: Nov 2007Est. completion: Nov 201252 patients
N/ACompleted
NCT02117596Pfizerimmunosuppression

Calcineurin Inhibitor Based Immunosuppression Withdrawal

Start: Nov 2007Est. completion: Nov 201252 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.