Partial Lipodystrophy

2
Pipeline Programs
1
Companies
2
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

1 companies ranked by most advanced pipeline stage

AP
Amryt PharmaUK - London
2 programs
1
1
MetreleptinPhase 41 trial
metreleptinPhase 31 trial
Active Trials
NCT05164341Active Not Recruiting69Est. Oct 2026
NCT06484868Recruiting12Est. Feb 2028

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
Amryt PharmaMetreleptin
Amryt Pharmametreleptin

Clinical Trials (2)

Total enrollment: 81 patients across 2 trials

Open-label Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy

Start: Feb 2024Est. completion: Feb 202812 patients
Phase 4Recruiting

Study to Evaluate the Safety and Efficacy of Daily Subcutaneous Metreleptin Treatment in Subjects With PL

Start: Dec 2021Est. completion: Oct 202669 patients
Phase 3Active Not Recruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 81 patients
1 companies competing in this space