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Part 1:r/r B-cell Malignancies

0
Pipeline Programs
1
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
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0
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%

Competitive Landscape

1 companies ranked by most advanced pipeline stage

InnoCare
InnoCareChina - Beijing
1 program
OrelabrutinibPHASE_1_2Small Molecule4 trials
Active Trials
NCT07896590Not Yet Recruiting292Est. Jan 2032
NCT07784101Not Yet Recruiting280Est. Dec 2033
NCT07480863Active Not Recruiting65Est. Oct 2029
+1 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
InnoCareOrelabrutinib
InnoCareOrelabrutinib
InnoCareOrelabrutinib
InnoCareOrelabrutinib

Clinical Trials (4)

Total enrollment: 718 patients across 4 trials

NCT07896590InnoCareOrelabrutinib

Orelabrutinib Plus ICP 248 vs Orelabrutinib for Relapsed/Refractory Marginal Zone Lymphoma

Start: Oct 2026Est. completion: Jan 2032292 patients
Phase 3Not Yet Recruiting
NCT07784101InnoCareOrelabrutinib

A Phase 3 Study to Compare the Efficacy of ICP-248 in Combination With Orelabrutinib Versus Pirtobrutinib in Participants With Relapsed or Refractory Mantle Cell Lymphoma (r/r MCL).

Start: Oct 2026Est. completion: Dec 2033280 patients
Phase 3Not Yet Recruiting
NCT07480863InnoCareOrelabrutinib

Treatment of Orelabrutinib+Hi-CVP Regimen for Previously Untreated MZL

Start: Oct 2025Est. completion: Oct 202965 patients
Phase 2Active Not Recruiting
NCT04014205InnoCareOrelabrutinib

A Study of Tyrosine Kinase Inhibitor Orelabrutinib (ICP-022) in Patients With r/r B-Cell Malignancies

Start: Nov 2019Est. completion: Jun 202681 patients
Phase 1/2Active Not Recruiting

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.