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Parenteral Nutrition

7
Pipeline Programs
5
Companies
13
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
1
3
2
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

5 companies ranked by most advanced pipeline stage

B. Braun
B. BraunGermany - Melsungen
5 programs
3
2
LipidemPhase 43 trials
LipoplusPhase 41 trial
Lipofundin MCTPhase 32 trials
NuTRIflex Lipid periPhase 31 trial
fish oil containing lipid emulsionPhase 31 trial
Active Trials
NCT00798447Completed100Est. Oct 2010
NCT00530738Completed42Est. Jan 2014
NCT01247740Completed240Est. Oct 2011
+5 more trials
Baxter
BaxterCosta Rica - Cartago
2 programs
1
1
ClinOleic 20% Intravenous EmulsionPhase 2/3
Sodium GlycerophosphatePhase 1
Baxter International
3 programs
Numeta G16%EPHASE_11 trial
Sodium Glycerophosphate InjectionPHASE_11 trial
ClinOleic 20% Intravenous EmulsionPHASE_2_31 trial
Active Trials
NCT06842134Completed16Est. May 2025
NCT06842121Completed42Est. May 2025
NCT00672854Completed100Est. Dec 2010
Fresenius Kabi
Fresenius KabiGermany - Bad Homburg
2 programs
SMOF lipid and IntralipidPHASE_31 trial
SmofKabiven emulsion for infusionPHASE_31 trial
Active Trials
NCT00451646Completed75Est. Nov 2008
NCT03792100Completed273Est. Jan 2020
Parexel
ParexelMA - Boston
1 program
SmofKabiven emulsion for infusionPHASE_3

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
B. BraunLipidem
B. BraunLipoplus
B. BraunLipofundin MCT
Fresenius KabiSmofKabiven emulsion for infusion
B. BraunNuTRIflex Lipid peri
B. Braunfish oil containing lipid emulsion
B. BraunLipofundin MCT
Fresenius KabiSMOF lipid and Intralipid
Baxter InternationalClinOleic 20% Intravenous Emulsion
B. BraunLipidem
B. BraunLipidem
Baxter InternationalSodium Glycerophosphate Injection
Baxter InternationalNumeta G16%E

Clinical Trials (13)

Total enrollment: 1,273 patients across 13 trials

The HOME Study (HPN With OMEGA-3)

Start: Jan 2018Est. completion: Jul 202274 patients
Phase 4Completed

Different Lipid Emulsions in Acute Lung Injury Patients

Start: Mar 2013Est. completion: May 20151 patients
Phase 4Terminated
NCT00530738B. BraunLipofundin MCT

Safety and Efficacy of Longterm HPN With Two Lipid Emulsions

Start: Sep 2007Est. completion: Jan 201442 patients
Phase 4Completed
NCT03792100Fresenius KabiSmofKabiven emulsion for infusion

Efficacy & Safety of SmofKabiven Emulsion for Infusion vs Hospital Compounded "All in One" for Parenteral Nutrition

Start: Jan 2019Est. completion: Jan 2020273 patients
Phase 3Completed
NCT01247740B. BraunNuTRIflex Lipid peri

Comparison of Three-chamber-bag Versus Compounded Bag

Start: Oct 2010Est. completion: Oct 2011240 patients
Phase 3Completed
NCT01176695B. Braunfish oil containing lipid emulsion

Efficacy and Safety of a Fish Oil Containing Lipid Emulsion

Start: Apr 2010Est. completion: Apr 2011240 patients
Phase 3Completed
NCT00798447B. BraunLipofundin MCT

Efficacy and Safety of a PN Regimen Containing n-3 Fatty Acid in Patients Considered After GI Surgery

Start: Nov 2008Est. completion: Oct 2010100 patients
Phase 3Completed
NCT00451646Fresenius KabiSMOF lipid and Intralipid

Study Comparing the Safety and Tolerance of SMOFlipid 20% in Long-term Treatment With Parenteral Nutrition

Start: Oct 2007Est. completion: Nov 200875 patients
Phase 3Completed
NCT00672854Baxter InternationalClinOleic 20% Intravenous Emulsion

Study Comparing a Soybean Oil-Based With an Olive Oil-Based Lipid Emulsion in ICU Patients Requiring TPN

Start: Nov 2008Est. completion: Dec 2010100 patients
Phase 2/3Completed

A Study of the Effect of Gemcitabine With Fish Oil in Patients With Advanced Pancreatic Cancer

Start: Oct 2009Est. completion: Jun 201450 patients
Phase 2Completed

The Effect of Fish Oils on Human Hepatic Colorectal Metastases

Start: May 2007Est. completion: Oct 201020 patients
Phase 2Completed
NCT06842121Baxter InternationalSodium Glycerophosphate Injection

A Bioequivalence Study Comparing Organic Phosphate (Sodium Glycerophosphate Injection) to Inorganic Phosphate (Sodium Phosphates Injection, USP)

Start: Jan 2025Est. completion: May 202542 patients
Phase 1Completed

A Study Comparing Organic Phosphate (Sodium Glycerophosphate Injection) to Numeta G16%E

Start: Jan 2025Est. completion: May 202516 patients
Phase 1Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 late-stage (Phase 3) programs, potential near-term approvals
5 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.