Panic Disorder
7
Pipeline Programs
3
Companies
5
Clinical Trials
4
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
6
Early DiscoveryClinical DevelopmentMarket
On Market (4)
Approved therapies currently available
UP
UP
U
LEVETIRACETAMApproved
levetiracetam
Unknown Companyoral2012
U
SPRITAMApproved
levetiracetam
Unknown Companyoral2015
Competitive Landscape
3 companies ranked by most advanced pipeline stage
UP
Jerusalem PharmaceuticalsIsrael - Ramallah
2 programsCBT- both internet and face to faceN/A1 trial
ICBT for panic and depressionN/A1 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
Pfizersertraline
Pfizeralprazolam XR
UCB Pharmalevetiracetam
Jerusalem PharmaceuticalsCBT- both internet and face to face
Jerusalem PharmaceuticalsICBT for panic and depression
Clinical Trials (5)
Total enrollment: 595 patients across 5 trials
A Study Of Sertraline Compared With Paroxetine In The Treatment Of Panic Disorder
Start: May 2008Est. completion: Feb 2010321 patients
Phase 4Completed
A Study To Assess the Safety of Extended Release Alprazolam for the Treatment of Adolescents With Panic Disorder or Anxiety With Panic Attacks
Start: May 2004Est. completion: Oct 200449 patients
Phase 4Terminated
Levetiracetam Treatment of Panic Disorder and Lactate-Induced Panic Attacks
Start: Jan 2006Est. completion: Mar 200915 patients
Phase 3Completed
Exosomal microRNAs as a Biomarker in Panic Disorder and in Response to CBT
Start: Mar 2019Est. completion: Dec 202180 patients
N/AUnknown
Attitudes of Professionals and the General Public in Israel Regarding ICBT
Start: Nov 2016Est. completion: Jan 2022130 patients
N/ACompleted
Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
1 late-stage (Phase 3) programs — potential near-term approvals
3 companies competing in this space