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Painful Osteoarthritis of the Knee

2
Pipeline Programs
2
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

AstraZeneca
AstraZenecaCAMBRIDGE, United Kingdom
2 programs
1
1
MEDI7352Phase 21 trial
MEDI7352Phase 11 trial
Active Trials
NCT04770428Completed24Est. Dec 2021
NCT04675034Completed345Est. Aug 2023
Frontera Therapeutics
Frontera TherapeuticsChina - Suzhou
1 program
RF treatmentN/A1 trial
Active Trials
NCT02688543Completed25Est. Jan 2016

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
AstraZenecaMEDI7352
AstraZenecaMEDI7352
Frontera TherapeuticsRF treatment

Clinical Trials (3)

Total enrollment: 394 patients across 3 trials

A Study of the Efficacy and Safety of MEDI7352 in Participants With Painful Osteoarthritis of the Knee

Start: Dec 2020Est. completion: Aug 2023345 patients
Phase 2Completed

Evaluate Safety, Tolerability, Pharmacokinetics and Immunogenicity of MEDI7352 in Healthy Volunteers

Start: Apr 2021Est. completion: Dec 202124 patients
Phase 1Completed

Radiofrequency Ablation of Genicular Nerves for Advanced Osteoarthrosis of the Knee Joint 1 Year Follow-up.

Start: Mar 2013Est. completion: Jan 201625 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.