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Oxidative Stress

5
Pipeline Programs
10
Companies
11
Clinical Trials
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
3
0
0
1
Early DiscoveryClinical DevelopmentMarket

On Market (1)

Approved therapies currently available

Takeda
DUETACTApproved
pioglitazone and glimepiride
Takeda
Sulfonylurea [EPC]oral2006

Competitive Landscape

10 companies ranked by most advanced pipeline stage

Takeda
TakedaTOKYO, Japan
1 program
1
DUETACT(Pioglitazone)PHASE_21 trial
Active Trials
NCT00771004Completed63Est. Feb 2009
Human BioSciences
Human BioSciencesWV - Martinsburg
2 programs
1
Oxytocin nasal sprayPhase 2
Titration of oxygen during neonatal resuscitationN/A1 trial
Active Trials
NCT03115463Completed75Est. Sep 2022
Medica Corp
Medica CorpMA - Bedford
1 program
1
Angiotensin converting enzyme inhibitorPhase 21 trial
Active Trials
NCT05232370Completed39Est. Jan 2022
Cognition Therapeutics
Cognition TherapeuticsPA - Pittsburgh
1 program
1
Oxytocin nasal sprayPhase 21 trial
Active Trials
NCT04732247Completed40Est. Sep 2023
Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
1 program
1
6 mg xanthohumol per dayPhase 11 trial
Active Trials
NCT02432651Completed64Est. Jun 2017
Lonza
LonzaBasel, Switzerland
3 programs
Cross Training CourseN/A1 trial
OceanixN/A1 trial
Oceanix®N/A1 trial
Active Trials
NCT04314596Completed18Est. Feb 2020
NCT04136821Completed25Est. Jan 2020
NCT04315077Completed22Est. Nov 2019
Forte Biosciences
1 program
MilkN/A1 trial
Active Trials
NCT03821116Completed84Est. Jun 2020
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
1 program
Normal Values of Oxidative Stress, Taurine, and Related MarkersN/A1 trial
Active Trials
NCT02649777Completed22Est. Dec 2017
Defence Therapeutics
Defence TherapeuticsBC - Vancouver
1 program
OxygenN/A1 trial
Active Trials
NCT02577692Unknown20Est. Nov 2019
Genomics
GenomicsUK - Oxford
1 program
Oxytocin nasal sprayPHASE_2

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Cognition TherapeuticsOxytocin nasal spray
Medica CorpAngiotensin converting enzyme inhibitor
TakedaPioglitazone
Oregon Therapeutics6 mg xanthohumol per day
LonzaCross Training Course
LonzaOceanix®
LonzaOceanix
Forte BiosciencesMilk
Human BioSciencesTitration of oxygen during neonatal resuscitation
Defence TherapeuticsOxygen
Colorado TherapeuticsNormal Values of Oxidative Stress, Taurine, and Related Markers

Clinical Trials (11)

Total enrollment: 472 patients across 11 trials

Oxytocin for Oxidative Stress and Inflammation

Start: Feb 2022Est. completion: Sep 202340 patients
Phase 2Completed
NCT05232370Medica CorpAngiotensin converting enzyme inhibitor

The Effect of Enalapril, Losartan or Not Antihypertensive on the Oxidative Status in Renal Transplant Recipients

Start: Jan 2022Est. completion: Jan 202239 patients
Phase 2Completed
NCT00771004TakedaPioglitazone

Efficacy of Pioglitazone on Myocardial Function in Patients Undergoing Coronary Stent Implantation.

Start: Aug 2006Est. completion: Feb 200963 patients
Phase 2Completed
NCT02432651Oregon Therapeutics6 mg xanthohumol per day

Xanthohumol and Prevention of DNA Damage

Start: Mar 2015Est. completion: Jun 201764 patients
Phase 1Completed
NCT04314596LonzaCross Training Course

The Effects of Antioxidant Supplementation on Multiple Endurance Race Performance, Physiology, and Recovery.

Start: Jan 2020Est. completion: Feb 202018 patients
N/ACompleted

The Short Term Effects of Oceanix Supplementation on Recovery

Start: Oct 2019Est. completion: Nov 201922 patients
N/ACompleted

The Long-term Effects of Oceanix™ on Resistance Training Adaptations

Start: Sep 2019Est. completion: Jan 202025 patients
N/ACompleted

Milk and Soured Milk (filmjölk) Intervention on Oxidative Stress and Inflammation

Start: Jan 2019Est. completion: Jun 202084 patients
N/ACompleted
NCT03115463Human BioSciencesTitration of oxygen during neonatal resuscitation

Saturation Targets and Resuscitation in Preterm Trial

Start: Sep 2017Est. completion: Sep 202275 patients
N/ACompleted

Inspired Oxygen on Oxidative Stress and Breath Volatile Organic Compound Composition in Healthy Volunteers

Start: May 2016Est. completion: Nov 201920 patients
N/AUnknown
NCT02649777Colorado TherapeuticsNormal Values of Oxidative Stress, Taurine, and Related Markers

Normal Values of Oxidative Stress, Taurine, and Related Markers

Start: Jan 2016Est. completion: Dec 201722 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

10 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.

Oxidative Stress | Pipeline & Competitive Landscape | Formulate